全文获取类型
收费全文 | 5333篇 |
免费 | 504篇 |
国内免费 | 2篇 |
出版年
2023年 | 25篇 |
2022年 | 42篇 |
2021年 | 88篇 |
2020年 | 65篇 |
2019年 | 73篇 |
2018年 | 77篇 |
2017年 | 90篇 |
2016年 | 140篇 |
2015年 | 236篇 |
2014年 | 265篇 |
2013年 | 329篇 |
2012年 | 406篇 |
2011年 | 375篇 |
2010年 | 253篇 |
2009年 | 208篇 |
2008年 | 305篇 |
2007年 | 317篇 |
2006年 | 275篇 |
2005年 | 259篇 |
2004年 | 225篇 |
2003年 | 223篇 |
2002年 | 231篇 |
2001年 | 102篇 |
2000年 | 105篇 |
1999年 | 99篇 |
1998年 | 63篇 |
1997年 | 51篇 |
1996年 | 58篇 |
1995年 | 49篇 |
1994年 | 55篇 |
1993年 | 43篇 |
1992年 | 44篇 |
1991年 | 47篇 |
1990年 | 57篇 |
1989年 | 53篇 |
1988年 | 56篇 |
1987年 | 30篇 |
1986年 | 27篇 |
1985年 | 33篇 |
1984年 | 31篇 |
1983年 | 26篇 |
1982年 | 21篇 |
1981年 | 25篇 |
1979年 | 31篇 |
1978年 | 23篇 |
1977年 | 20篇 |
1976年 | 21篇 |
1975年 | 14篇 |
1974年 | 14篇 |
1973年 | 24篇 |
排序方式: 共有5839条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
7.
Daniel Hohl Barbara Ruf Olano Pierre A. de Viragh Marcel Huber Carol J. Detrisac Urs W. Schnyder Dennis R. Roop 《Differentiation; research in biological diversity》1993,54(3):25-34
Abstract. In this study we analyzed the expression patterns of loricrin in various species and tissues using immunohistochemistry, immunoblotting and Northern blots. Loricrin is a glycine-, serine- and cysteine-rich protein expressed very late in epidermal differentiation in the granular layers of normal mouse and human epidermis. Later on in differentiation, loricrin becomes cross-linked as a major component into the cornified cell envelope by the formation of Nɛ -(γ-glutamyl)lysine isopeptide bonds. This process either occurs directly or by the intermediate accumulation in L-keratohyaline granules of mouse epidermis and human acrosyringia. Loricrin was identified in all mammalian species analyzed by virtue of its highly conserved carboxy-terminal sequences revealing an electric mobility of ∼60 kDa in rodents, rabbit and cow and of ∼35 kDa in lamb and human on sodium dodecyl sulfate polyacrylamide gel electrophoresis. Loricrin is expressed in the granular layer of all mammalian orthokeratinizing epithelia tested including oral, esophageal and fore-stomach mucosa of rodents, tracheal squamous metaplasia of vitamin A deficient hamster and estrogen induced squamous vaginal epithelium of ovary ectomized rats. Loricrin is also expressed in a few parakeratinizing epithelia such as BBN [N-butyl-N-(4–hydroxybutyl)nitrosamine]-induced murine bladder carcinoma and a restricted subset of oral and single vaginal epithelial cells in higher mammals. Our results provide further evidence that the program of squamous differentiation in internal epithelia of the upper alimentary tract in rodents and higher mammals differ remarkably. In addition, we also have noted the distinct distribution patterns of human loricrin and involucrin, another major precursor protein of the cornified cell envelope. 相似文献
8.
Except at very low levels, uncorrected photometric determination of bacterial cell densities showed a decreasing proportionally to actual cell density or dry weight. A standard curve was prepared to convert photometric readings to truly proportional optical density values. With one dry weight determination, optical density values may be converted to absolute dry weight values. 相似文献
9.
10.