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It was shown, that influence of vitamin E on mineral and D-vitamin metabolism depends on its doses and application period: physiological doses of vitamin E activate and large doses - inhibit the effect of vitamin D3 in regulation of mineral metabolism in the organism. The duration of application of large doses of vitamin E (higher than 20 physiological doses) during which the negative changes are not determined has not to exceed 10 days.  相似文献   
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