全文获取类型
收费全文 | 10114篇 |
免费 | 1006篇 |
国内免费 | 6篇 |
出版年
2022年 | 90篇 |
2021年 | 134篇 |
2020年 | 96篇 |
2019年 | 118篇 |
2018年 | 134篇 |
2017年 | 159篇 |
2016年 | 222篇 |
2015年 | 366篇 |
2014年 | 487篇 |
2013年 | 584篇 |
2012年 | 735篇 |
2011年 | 663篇 |
2010年 | 421篇 |
2009年 | 374篇 |
2008年 | 507篇 |
2007年 | 518篇 |
2006年 | 486篇 |
2005年 | 467篇 |
2004年 | 444篇 |
2003年 | 397篇 |
2002年 | 403篇 |
2001年 | 174篇 |
2000年 | 171篇 |
1999年 | 147篇 |
1998年 | 117篇 |
1997年 | 98篇 |
1996年 | 100篇 |
1995年 | 91篇 |
1994年 | 103篇 |
1993年 | 85篇 |
1992年 | 159篇 |
1991年 | 116篇 |
1990年 | 106篇 |
1989年 | 114篇 |
1988年 | 125篇 |
1987年 | 112篇 |
1986年 | 85篇 |
1985年 | 130篇 |
1984年 | 118篇 |
1983年 | 101篇 |
1982年 | 73篇 |
1981年 | 72篇 |
1979年 | 68篇 |
1978年 | 77篇 |
1976年 | 56篇 |
1975年 | 56篇 |
1974年 | 65篇 |
1973年 | 63篇 |
1972年 | 52篇 |
1971年 | 53篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Denise Risch Nicholas J. Gales Jason Gedamke Lars Kindermann Douglas P. Nowacek Andrew J. Read Ursula Siebert Ilse C. Van Opzeeland Sofie M. Van Parijs Ari S. Friedlaender 《Biology letters》2014,10(4)
For decades, the bio-duck sound has been recorded in the Southern Ocean, but the animal producing it has remained a mystery. Heard mainly during austral winter in the Southern Ocean, this ubiquitous sound has been recorded in Antarctic waters and contemporaneously off the Australian west coast. Here, we present conclusive evidence that the bio-duck sound is produced by Antarctic minke whales (Balaenoptera bonaerensis). We analysed data from multi-sensor acoustic recording tags that included intense bio-duck sounds as well as singular downsweeps that have previously been attributed to this species. This finding allows the interpretation of a wealth of long-term acoustic recordings for this previously acoustically concealed species, which will improve our understanding of the distribution, abundance and behaviour of Antarctic minke whales. This is critical information for a species that inhabits a difficult to access sea-ice environment that is changing rapidly in some regions and has been the subject of contentious lethal sampling efforts and ongoing international legal action. 相似文献
3.
C Chong-Cerrillo M E Selsted E M Peterson L M de la Maza 《The journal of peptide research》2003,61(5):237-242
Four antimicrobial peptides, protegrin-1, RTD-1, cryptdin-4, and indolicidin, were tested for their ability to inhibit the in vitro growth of Chlamydia trachomatis serovars E, L2, and mouse pneumonitis (MoPn). In general, protegrin-1 was found to have the strongest anti-chlamydial activity. Overall, of the three serovars tested, L2 was the most susceptible while MoPn was the most resistant to these peptides. 相似文献
4.
5.
M C Peterson 《The Western journal of medicine》1994,161(2):148
Campylobacter jejuni is an almost ubiquitous, microaerophilic, gram-negative rod. Outbreaks have been associated with drinking raw milk or contaminated water and eating poultry. Campylobacter jejuni accounts for 3.2% to 6.1% of cases of diarrheal illness in the general population of the United States, and infected patients frequently present with abdominal pain and fever. Less frequently, C jejuni is responsible for bacteremia, septic arthritis, septic abortion, and other extraintestinal infections. Reactive arthritis, Reiter''s syndrome, the Guillain-Barré syndrome, and pancreatitis may accompany or follow C jejuni enterocolitis. Campylobacter jejuni is an important cause of diarrheal illness and is a more commonly identified stool organism than Salmonella or Shigella species. Recurrent and chronic infection is generally reported in immunocompromised hosts. 相似文献
6.
Kirsten Skamstrup Hansen Stefan Vieths Helle Vestergaard Per Stahl Skov Carsten Bindslev-Jensen Lars K. Poulsen 《Journal of chromatography. B, Analytical technologies in the biomedical and life sciences》2001,756(1-2)
The aim of the study was to investigate the possibility of a seasonal variation in reactivity to apples in 27 birch pollen allergic patients. Before and during the birch pollen season 1998, the patients were subjected to double-blind, placebo-controlled food challenges (DBPCFCs) with grated fresh Golden Delicious apple followed by an open food challenge with whole fresh apple. The clinical reactions elicited during the challenges were evaluated both by the patients and the investigators. Moreover, the skin reactivity and the in vitro reactivity to apple were evaluated by skin prick test (SPT), leukocyte histamine release (HR), measurement of specific IgE, and immunoblotting experiments. The sensitivity of the DBPCFC, when compared with the result of the open challenge, was 0.74 (14/19) before the season and 0.80 (16/20) during the season. None of the patients reacted to the blinded challenge without a subsequent reaction to the open challenge. One placebo reaction was registered both before and in season, but not in the same patient. The patient scores of the first positive challenges, and the maximal scores of each combined blinded and open challenge session, were significantly increased during the pollen season (P<0.05). The scores of the open challenge were significantly higher than the scores of the DBPCFC both before the season and during the in-season challenges (P<0.05). Specific IgE against Golden Delicious increased during season (P<0.05), while neither SPT, HR, nor immunoblotting experiments could confirm an increase in reactivity. In conclusion, the results of the oral challenge tests indicated an increase in clinical reactivity to apples during the birch pollen season in birch pollen allergic individuals. 相似文献
7.
8.
9.
10.
Riccardo E. Marioni Lars Penke Gail Davies Jennifer E. Huffman Caroline Hayward Ian J. Deary 《Proceedings. Biological sciences / The Royal Society》2014,281(1781)
Human cognitive ability shows consistent, positive associations with fitness components across the life-course. Underlying genetic variation should therefore be depleted by selection, which is not observed. Genetic variation in general cognitive ability (intelligence) could be maintained by a mutation–selection balance, with rare variants contributing to its genetic architecture. This study examines the association between the total number of rare stop-gain/loss, splice and missense exonic variants and cognitive ability in childhood and old age in the same individuals. Exome array data were obtained in the Lothian Birth Cohorts of 1921 and 1936 (combined N = 1596). General cognitive ability was assessed at age 11 years and in late life (79 and 70 years, respectively) and was modelled against the total number of stop-gain/loss, splice, and missense exonic variants, with minor allele frequency less than or equal to 0.01, using linear regression adjusted for age and sex. In both cohorts and in both the childhood and late-life models, there were no significant associations between rare variant burden in the exome and cognitive ability that survived correction for multiple testing. Contrary to our a priori hypothesis, we observed no evidence for an association between the total number of rare exonic variants and either childhood cognitive ability or late-life cognitive ability. 相似文献