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Elham Gholipour Houman Kahroba Nasim Soltani Parisa Samadi Parisa Sarvarian Sajjad VakiliSamiani Abbas Ali Hosein Pour Feizi Mohammad
Sadegh SoltaniZangbar Adel Baghersalimi Bahram Darbandi Aliakbar Movassaghpour Mehdi Talebi Roza Motavalli Amir Mehdizadeh Abdolhassan Kazemi Mehdi Yousefi 《Journal of cellular and molecular medicine》2022,26(16):4566
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Cynthia Aslan Sepideh Maralbashi Farhad Salari Houman Kahroba Faraz Sigaroodi Tohid Kazemi Pedram Kharaziha 《Journal of cellular physiology》2019,234(10):16885-16903
Tumor cells utilize different strategies to communicate with neighboring tissues for facilitating tumor progression and invasion, one of these strategies has been shown to be the release of exosomes. Exosomes are small nanovesicles secreted by all kind of cells in the body, especially cancer cells, and mediate cell to cell communications. Exosomes play an important role in cancer invasiveness by harboring various cargoes that could accelerate angiogenesis. Here first, we will present an overview of exosomes, their biology, and their function in the body. Then, we will focus on exosomes derived from tumor cells as tumor angiogenesis mediators with a particular emphasis on the underlying mechanisms in various cancer origins. Also, exosomes derived from stem cells and tumor-associated macrophages will be discussed in this regard. Finally, we will discuss the novel therapeutic strategies of exosomes as drug delivery vehicles against angiogenesis. 相似文献
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