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Andrea J Robinson Jomana Elaridi Bianca J Van Lierop Selma Mujcinovic W Roy Jackson 《Journal of peptide science》2007,13(4):280-285
Microwave irradiation dramatically improves the efficiency of ring closing metathesis (RCM) reactions of resin-attached peptides and the technology is illustrated by the highly selective synthesis of dicarba analogues of alpha-conotoxin IMI. 相似文献
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Ehsan Mohammadpour Jomana Al-Nu’airat Zhong-Tao Jiang Nicholas Mondinos Bogdan Z. Dlugogorski 《Molecular simulation》2018,44(5):415-423
The equilibrium structure, elastic constants Cij and thermodynamic functions of cubic titanium nitride (TiN) were calculated within the temperature range of 0–3100 K and under a pressure range 0–60 GPa. Properties were computed using the generalised gradient approximations (GGA) exchange-correlation functional. Calculated mechanical properties (Elastic constants, Young’s modulus and shear modulus) and phonon spectra of TiN obtained via robust DFT-QHA algorithm, were generally in a good agreement with available experimental and theoretical analogous values. In particular, a well-examined quasi-harmonic approximation method implemented in the Gibbs2 code is utilised herein to provide accurate estimation of thermal expansion coefficients, entropies, heat capacity values (at different combinations of temperature/volume/pressure) and Debye’s temperature. Parameters calculated herein shall be useful to elucidate the superior performance of TiN at harsh operational conditions encompassing elevated temperatures and pressures pertinent to cutting machineries and surface coatings. 相似文献
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DeStefano AL Latourelle J Lew MF Suchowersky O Klein C Golbe LI Mark MH Growdon JH Wooten GF Watts R Guttman M Racette BA Perlmutter JS Marlor L Shill HA Singer C Goldwurm S Pezzoli G Saint-Hilaire MH Hendricks AE Gower A Williamson S Nagle MW Wilk JB Massood T Huskey KW Baker KB Itin I Litvan I Nicholson G Corbett A Nance M Drasby E Isaacson S Burn DJ Chinnery PF Pramstaller PP Al-Hinti J Moller AT Ostergaard K Sherman SJ Roxburgh R Snow B Slevin JT Cambi F Gusella JF Myers RH 《Human genetics》2008,124(1):95-99
Genetic variants in embryonic lethal, abnormal vision, Drosophila-like 4 (ELAVL4) have been reported to be associated with onset age of Parkinson disease (PD) or risk for PD affection in Caucasian populations.
In the current study we genotyped three single nucleotide polymorphisms in ELAVL4 in a Caucasian study sample consisting of 712 PD patients and 312 unrelated controls from the GenePD study. The minor allele of rs967582 was associated with increased risk of PD (odds ratio = 1.46, nominal P value = 0.011) in the GenePD population. The minor allele of rs967582 was also the risk allele for PD affection or earlier onset age in the previously
studied populations. This replication of association with rs967582 in a third cohort further implicates ELAVL4 as a PD susceptibility gene. 相似文献
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