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Russian Journal of Plant Physiology - Due to the antifungal and antibacterial properties, silver nanoparticles (AgNPs) are now widely used in consumer products. In this research, the effects of... 相似文献
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Mehdi Moghanibashi Ferdous Rastgar Jazii Zahra-Soheila Soheili Maryam Zare Aliasghar Karkhane Kazem Parivar Parisa Mohamadynejad 《Functional & integrative genomics》2013,13(2):253-260
Nuclear pore complex (NPC) is the only corridor for macromolecules exchange between nucleus and cytoplasm. NPC and its components, nucleoporins, play important role in the diverse physiological processes including macromolecule exchange, chromosome segregation, apoptosis and gene expression. Recent reports also suggest involvement of nucleoporins in carcinogenesis. Applying proteomics, we analyzed expression pattern of the NPC components in a newly established esophageal cancer cell line from Persia (Iran), the high-risk region for esophageal cancer. Our results indicate overexpression of Hsc70 and downregulation of subunit alpha type-3 of proteasome, calpain small subunit 1, and eIF5A-1. Among these proteins, Hsc70 and eIF5A-1 are in direct interaction with NPC and involved in the nucleocytoplasmic exchange. Hsc70 plays a critical role as a chaperone in the formation of a cargo–receptor complex in nucleocytoplasmic transport. On the other hand, it is an NPC-associated protein that binds to nucleoporins and contributes in recycling of the nucleocytoplasmic transport receptors in mammals and affects transport of proteins between nucleus and cytoplasm. The other nuclear pore interacting protein: eIF5A-1 binds to the several nucleoporins and participates in nucleocytoplasmic transport. Altered expression of Hsc70 and eIF5A-1 may cause defects in nucleocytoplasmic transport and play a role in esophageal carcinogenesis. 相似文献
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Prof. Dr. Habil. Karl Schumann Dipl. Agr. Ing. Klaus-Stefan Kühne 《Archives Of Phytopathology And Plant Protection》2013,46(5):465-472
Schwantes, H.O.: Biologie der Pilze. Eine Einführung in die angewandte Mykologie. 478 S., 60 Abb., 29 Tab. Verlag Eugen Ulmer, Stuttgart, 1996, UNI‐Taschenbücher 1871, 42,80 DM. ISBN 3–8252–1871–6 Westhoff, P.; Jeske, H.; Jürgens, G.; Kloppstock, K.; Link, G.: Molekulare Entwicklungsbiologie. Vom Gen zur Pflanze. Georg Thieme Verlag Stuttgart, New York; 1996; 112 Abb., 19 Tab. ISBN 3–13–102021–0 McNamara, K.J. (Herausgeber): Evolutionary Change and Heterochrony. John Wiley &; Sons; Chichester, New York, Brisbane, Toronto, Singapur (1995), ISBN 0–471–95837–9 Sobral, B.W.S. (Herausgeber): The Impact of Plant Molecular Genetics. Birkhäuser Verlag AG Basel (1996), ISBN 3–7643–3802–4 McIntosh, R.A.; Wellings, C.R.; Park, R.F.: Wheat rusts ‐ An atlas of resistance genes. 200 S., 119 Bildseiten, Kluwer Academic Publishers, Dordrecht, Boston, London, 1995, 125,00 Dfl., ISBN 0–7923–3430–2 Friedrich, G.; Rode, H. (Hsg.): Pflanzenschutz im integrierten Obstbau. Verlag Eugen Ulmer Stuttgart. 1996. 494 S., 128 Farbfotos, 94 Zeichnungen, 41 Tab., 3. völlig neubearbeitete Auflage. Preis 88,‐DM; ISBN 3–8001–5541–9 Nultsch, W.: Allgemeine Botanik. 10. neubearbeitete erweiterte Auflage. Georg Thieme Verlag Stuttgart New York. 1996, 602 Seiten, 234 Abb. in 525 Einzeldarstellungen, 19 Boxen. Glossarium mit 752 Stichworten. Preis 44,‐DM; ISBN 3–13–383310–3 Berndt, J.: Umweltbiochemie. Uni‐Taschenbücher 1838. Gustav Fischer Verlag Stuttgart Jena. 1995; 278 S., 101 Abb., 33 Tab., Preis 34.80 DM. UTB‐ISBN 3–8252–1838–4 Kalusche, D.: Ökologie in Zahlen. Eine Datensammlung in Tabellen mit über 10.000 Einzelwerten. Gustav Fischer Verlag. Stuttgart, Jena, New York. 1996. 415 S. Preis 54, ‐DM; ISBN 3–437–20521–8 相似文献
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Habib Yaribeygi Vahid Zare Alexandra E. Butler George E. Barreto Amirhossein Sahebkar 《Journal of cellular physiology》2019,234(6):8610-8617
The prevalence of diabetes mellitus is growing rapidly worldwide. This metabolic disorder affects many physiological pathways and is a key underlying cause of a multitude of debilitating complications. There is, therefore, a critical need for effective diabetes management. Although many synthetic therapeutic glucose-lowering agents have been developed to control glucose homeostasis, they may have unfavorable side effects or limited efficacy. Herbal-based hypoglycemic agents present an adjunct treatment option to mitigate insulin resistance, improve glycemic control and reduce the required dose of standard antidiabetic medications. Saffron (Crocus sativus L.), whilst widely used as a food additive, is a natural product with insulin-sensitizing and hypoglycemic effects. Saffron contains several bioactive β carotenes, which exert their pharmacological effects in various tissues without any obvious side effects. In this study, we discuss how saffron and its major components exert their hypoglycemic effects by induction of insulin sensitivity, improving insulin signaling and preventing β-cell failure, all mechanisms combining to achieve better glycemic control. 相似文献
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Fatemeh Nasrollahi Shahrokh Kazempour‐Osaloo Nasim Saadati Valeyollah Mozaffarian Hassan Zare‐Maivan 《Nordic Journal of Botany》2019,37(1)
We analysed 87 species of Onosma (Boraginaceae) from throughout its distribution range to investigate its evolutionary history. Using nrDNA ITS and two plastid (rpl32‐trnL(UAG) and trnH–psbA) markers, we reconstructed phylogenetic relationships within Onosma by conducting maximum parsimony, maximum likelihood, Bayesian, and BEAST analyses. The analyses revealed that Onosma as currently circumscribed is not monophyletic. However, the vast majority of Onosma species appear to belong to a single clade, the so‐called Onosma s.s. Outside of this core clade is a clade containing O. rostellata, a subclade of Sino‐Indian species and Maharanga emodii. Podonosma orientalis (as O. orientalis) appear only distantly related to Onosma but is more closely related to Alkanna, as also suggested in previous molecular studies. The Onosma s.s. clade includes all representatives of O. sect. Onosma, and encompasses three subsections, i.e. Onosma, Haplotricha and Heterotricha, corresponding to asterotrichous, haplotrichous and heterotrichous groups, respectively, but none of these subsections was retrieved as monophyletic. We observed significant incongruence between nuclear and chloroplast phylogenies regarding the phylogenetic status of the heterotrichous group. A dozen of the Iranian haplotrichous species formed a lineage which may not hybridize with asterotrichous species. Divergence time estimates suggested that the early radiation of Onosma s.l. took place at the Oligocene‐Miocene boundary and the diversification within Onosma s.s. occurred during middle to late Miocene and Pliocene. 相似文献
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Khadijeh Zare Hossein Nazemiyeh Ali Movafeghi Mahmood Khosrowshahli Alireza Motallebi-Azar Mohammadreza Dadpour Yadollah Omidi 《Plant Cell, Tissue and Organ Culture》2010,100(2):157-164
An in vitro cell suspension culture of Echium italicum was established and assayed for the production of shikonin and alkannin derivatives. Callus tissues were induced from cotyledon
explants of the plant incubated onto the solidified B5 medium. A two-liquid-phase system suspension culture was then established
to elicit pigments of shikonin and alkannin derivatives using liquid paraffin. The presence of liquid paraffin efficiently
induced production of pigments in cultured cells. The production and/or accumulation of these compounds in the E. italicum cells was examined using fluorescence microscopy as the naphthoquinone molecules display autofluorescent properties. Phytochemical
analysis of the n-hexane extract of the medium was also carried out using preparative HPLC. The chemical structure of shikonin and alkannin
derivatives were characterized by UV, 1H-NMR, and 13C-NMR techniques. Based on our findings, this bioprocess engineering approach
resulted in induction of shikonin and alkannin derivatives, whereupon it may be recruited for production of these important
secondary metabolites. 相似文献
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Morphological and molecular analyses demonstrate that Coniolariella gamsii and Coniolaria murandii are distinct species. The latter species is validated here as Coniolariella macrothecia. A key to the five species of the genus is provided. 相似文献
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