全文获取类型
收费全文 | 144篇 |
免费 | 5篇 |
出版年
2016年 | 3篇 |
2013年 | 4篇 |
2011年 | 4篇 |
2010年 | 3篇 |
2009年 | 2篇 |
2008年 | 2篇 |
2007年 | 2篇 |
2006年 | 3篇 |
2001年 | 2篇 |
1997年 | 1篇 |
1994年 | 2篇 |
1993年 | 3篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 3篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1971年 | 3篇 |
1970年 | 1篇 |
1961年 | 3篇 |
1960年 | 2篇 |
1955年 | 1篇 |
1953年 | 2篇 |
1952年 | 1篇 |
1950年 | 3篇 |
1942年 | 2篇 |
1940年 | 4篇 |
1938年 | 1篇 |
1936年 | 18篇 |
1934年 | 1篇 |
1933年 | 13篇 |
1932年 | 8篇 |
1931年 | 11篇 |
1930年 | 1篇 |
1929年 | 4篇 |
1926年 | 1篇 |
1925年 | 1篇 |
1924年 | 1篇 |
1915年 | 1篇 |
排序方式: 共有149条查询结果,搜索用时 15 毫秒
1.
Background
Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in terms of the phylogenic tree. In a similar way it has been argued that biological networks also induce correlations among sets of interacting genes or their protein products. 相似文献2.
3.
南瓜雌蕊与自花及远缘花粉的相互作用 总被引:2,自引:0,他引:2
南瓜柱头表面经去垢剂、蛋白酶及Con A处理后花粉不能萌发或花粉管生长受阻,Con A能专一地与柱头表面结合。柱头块加入培养液可促进花粉萌发。不同的远缘花粉授粉后在雌蕊不同部位受阻。在成熟南瓜雌蕊提取液中检测到血凝活性,凝集素可能参与雌蕊对远缘花粉的抑制。 相似文献
4.
5.
I Diaz-Laviada P Larrodera J L Nieto M E Cornet M T Diaz-Meco M J Sanchez P H Guddal T Johansen A Haro J Moscat 《The Journal of biological chemistry》1991,266(2):1170-1176
The phospholipase C-mediated hydrolysis of phosphatidylcholine has been shown recently to be activated by a number of agonists. Muscarinic receptors, which trigger various signal transduction mechanisms including inhibition of adenylate cyclase through Gi, have been shown to be potent stimulants of this novel phospholipid degradative pathway. We demonstrate here, by exogenous addition of Bacillus cereus phosphatidylcholine-hydrolyzing phospholipase C, that phosphatidylcholine breakdown mimics the ability of carbachol to inhibit adenylate cyclase. This effect is sensitive to pertussis toxin and is entirely dependent on the presence of protein kinase C. This kinase is also required for the inhibition by carbachol of adenylate cyclase. These results suggest that the activation of phosphatidylcholine breakdown by phospholipase C may play an important role linking or favoring the coupling muscarinic receptors to Gi. Results presented here also show that phospholipase C-mediated hydrolysis of phosphoinositides by exogenous addition of Bacillus thuringiensis phosphoinositide-hydrolyzing phospholipase C does not affect adenylate cyclase, despite the fact that protein kinase C is translocated to an extent similar to that produced by the hydrolysis of phosphatidylcholine. According to the results shown here, both phospholipases also differ in their ability to down-regulate protein kinase C as well as to phosphorylate p80 and to transmodulate the binding of epidermal growth factor, two well established effects of protein kinase C in Swiss 3T3 fibroblasts. This emphasizes the complexity, from a functional point of view, of protein kinase C activation "in vivo." 相似文献
6.
7.
8.
9.
10.