全文获取类型
收费全文 | 435篇 |
免费 | 35篇 |
国内免费 | 1篇 |
专业分类
471篇 |
出版年
2023年 | 3篇 |
2022年 | 7篇 |
2021年 | 7篇 |
2020年 | 8篇 |
2019年 | 9篇 |
2018年 | 7篇 |
2017年 | 10篇 |
2016年 | 10篇 |
2015年 | 13篇 |
2014年 | 15篇 |
2013年 | 17篇 |
2012年 | 24篇 |
2011年 | 20篇 |
2010年 | 23篇 |
2009年 | 19篇 |
2008年 | 20篇 |
2007年 | 17篇 |
2006年 | 15篇 |
2005年 | 23篇 |
2004年 | 15篇 |
2003年 | 28篇 |
2002年 | 22篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1999年 | 5篇 |
1998年 | 3篇 |
1997年 | 5篇 |
1996年 | 7篇 |
1995年 | 8篇 |
1994年 | 5篇 |
1993年 | 4篇 |
1992年 | 9篇 |
1991年 | 3篇 |
1990年 | 4篇 |
1989年 | 7篇 |
1988年 | 5篇 |
1987年 | 2篇 |
1986年 | 4篇 |
1985年 | 5篇 |
1983年 | 4篇 |
1982年 | 7篇 |
1981年 | 3篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1978年 | 5篇 |
1977年 | 4篇 |
1976年 | 8篇 |
1974年 | 2篇 |
1972年 | 2篇 |
1970年 | 4篇 |
排序方式: 共有471条查询结果,搜索用时 15 毫秒
1.
2.
Summary This work addresses the problem of stable butanol formation byClostridium acetobutylicum in continuous culture. Sustained altered electron flow was observed in the presence of benzyl viologen which serves to redirect carbon flow towards primarily butanol formation. A yield of butanol of over 0.28 g.g–1 glucose was obtained and butanol comprised over 90% of the total solvents formed. Additionally, acid formation decreased significantly with butyric acid as the dominant acid end product. 相似文献
3.
The innervation of the distal and proximal heads of the accessory flexor muscle in three portunid crabs and two non-portunid decapods was studied electrophysiologically. In all species studied, the proximal head received only the two previously reported accessory flexor axons, an excitor and an inhibitor. The same two axons also innervated the distal head in all species, but in the portunids the distal head also received excitation from at least three, and probably sometimes four, of the main flexor excitor efferents. The accessory inhibitor exerted very strong effects in the tonic muscle fibers found in the proximal head and in the most proximal bundle of the distal head. The newly described inhibitory and excitatory distributions may have important implications for locomotory behavior. 相似文献
4.
Govind J. Kapadia Y.N. Shukla S.P. Basak Henry M. Fales E.A. Sokoloski 《Phytochemistry》1978,17(8):1444-1445
Melovinone, a new alkaloid isolated from the roots of Melochia tomentosa has been characterized as 3,7,8-trimethoxy-2-methyl-5(5′-phenylpentyl)-4-quinolinone. 相似文献
5.
6.
7.
Summary Controlled batch experiments performed withClostridium acetobutylicum show that methyl viologen induces solvent production at near neutral pH. At a pH of 6.8, significant ethanol production was observed in presence of methyl viologen. At pH 5, production of butanol and ethanol are favored at the expense of acetone. 相似文献
8.
Gwenaelle Gueguen Marta E. Kalamarz Johnny Ramroop Jeffrey Uribe Shubha Govind 《PLoS pathogens》2013,9(8)
Polydnaviruses are mutualists of their parasitoid wasps and express genes in immune cells of their Lepidopteran hosts. Polydnaviral genomes carry multiple copies of viral ankyrins or vankyrins. Vankyrin proteins are homologous to IκB proteins, but lack sequences for regulated degradation. We tested if Ichnoviral Vankyrins differentially impede Toll-NF-κB-dependent hematopoietic and immune signaling in a heterologous in vivo Drosophila, system. We first show that hematopoiesis and the cellular encapsulation response against parasitoid wasps are tightly-linked via NF-κB signaling. The niche, which neighbors the larval hematopoietic progenitors, responds to parasite infection. Drosophila NF-κB proteins are expressed in the niche, and non cell-autonomously influence fate choice in basal and parasite-activated hematopoiesis. These effects are blocked by the Vankyrin I2-vank-3, but not by P-vank-1, as is the expression of a NF-κB target transgene. I2-vank-3 and P-vank-1 differentially obstruct cellular and humoral inflammation. Additionally, their maternal expression weakens ventral embryonic patterning. We propose that selective perturbation of NF-κB-IκB interactions in natural hosts of parasitic wasps negatively impacts the outcome of hematopoietic and immune signaling and this immune deficit contributes to parasite survival and species success in nature. 相似文献
9.
10.
Seloame T. Nyaku Venkateswara R. Sripathi Ramesh V. Kantety Yong Q. Gu Kathy Lawrence Govind C. Sharma 《PloS one》2013,8(4)
The 18S rRNA gene is fundamental to cellular and organismal protein synthesis and because of its stable persistence through generations it is also used in phylogenetic analysis among taxa. Sequence variation in this gene within a single species is rare, but it has been observed in few metazoan organisms. More frequently it has mostly been reported in the non-transcribed spacer region. Here, we have identified two sequence variants within the near full coding region of 18S rRNA gene from a single reniform nematode (RN) Rotylenchulus reniformis labeled as reniform nematode variant 1 (RN_VAR1) and variant 2 (RN_VAR2). All sequences from three of the four isolates had both RN variants in their sequences; however, isolate 13B had only RN variant 2 sequence. Specific variable base sites (96 or 5.5%) were found within the 18S rRNA gene that can clearly distinguish the two 18S rDNA variants of RN, in 11 (25.0%) and 33 (75.0%) of the 44 RN clones, for RN_VAR1 and RN_VAR2, respectively. Neighbor-joining trees show that the RN_VAR1 is very similar to the previously existing R. reniformis sequence in GenBank, while the RN_VAR2 sequence is more divergent. This is the first report of the identification of two major variants of the 18S rRNA gene in the same single RN, and documents the specific base variation between the two variants, and hypothesizes on simultaneous co-existence of these two variants for this gene. 相似文献