Relationship between Neutrophins and Gut Microbiome in Various Metabolic Types of Obesity

Journal of Evolutionary Biochemistry and Physiology - Obesity is associated with a gut microbiome imbalance and the risk of neurological complications. However, the risk of complications is...     

Alkylresorcinols: New Potential Bioregulators in the Superorganism System (Human–Microbiota)

Biology Bulletin - Based on the results of qualitative and quantitative analysis of alkylresorcinol pools in the intestine and in the blood, as well as their correlations with the level of...     

Evaluation of energy metabolism and physical work capacity of divers for determining the optimal oxygen level during breathing gas mixture under pressure up to 5.1 MPa]

A complex evaluation of energy metabolism, oxygen-transport function of blood and physical work capacity of aquanauts has been performed during three imitation divings at depths of 400, 450 and 500 m in heliox as a breathing medium. These experiments have shown that optimal levels of partial oxygen pressure in artificial chamber environment are 30-33 kPa at 4.1 MPa, 32-35 kPa at 4.6 MPa and 33-34 kPa at 5.1 MPa. It is established that 24-days exposure of aquanautes to 4.6 MPa and 10-days exposure to 5.1 MPa yield no unfavourable changes of the examined organism functions. The activated lipid exchange in combination with stable carbohydrate catabolism, the elevated levels of oxygen consumption and its partial pressure in blood and transient fluctuations of erythropoiesis activity are interpreted as compensatory responses of diverse organisms under the influence of hyperbaric factors.     

Effect of hyperbaric factors on the biochemical and hematological indicators in rats (in vivo) and in humans (in vitro)]

The influence of hyperbaric factors on complex of biochemical and haematological parameters was examined in rats (in vivo) on donor blood samples. It was established, that the sojourn in heliox under the pressure 6.1 MPa and rO2 60 kPa results in activation of lipid peroxidation, alteration of erythrocyte oxygen transport function and the suppression of lipid metabolism. There are no significant alterations of these parameters in the comparative experiment with the pO2 40 kPa. The decompression of donor blood samples from 5.1 MPa to 0.1 MPa during 50 minutes had no significant influence on complex of biochemical, haematological and immunological parameters as compared to control probes.