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1.
Background
In heterogeneous environments, sex-biased dispersal could lead to environmental adaptive parental effects, with offspring selected to perform in the same way as the parent dispersing least, because this parent is more likely to be locally adapted. We investigate this hypothesis by simulating varying levels of sex-biased dispersal in a patchy environment. The relative advantage of a strategy involving pure maternal (or paternal) inheritance is then compared with a strategy involving classical biparental inheritance in plants and in animals. 相似文献2.
B?rbel Maus Camille Jung Jestinah M. Mahachie John Jean-Pierre Hugot Emmanuelle Génin Kristel Van Steen 《PloS one》2013,8(10)
Complex human diseases commonly differ in their phenotypic characteristics, e.g., Crohn’s disease (CD) patients are heterogeneous with regard to disease location and disease extent. The genetic susceptibility to Crohn’s disease is widely acknowledged and has been demonstrated by identification of over 100 CD associated genetic loci. However, relating CD subphenotypes to disease susceptible loci has proven to be a difficult task. In this paper we discuss the use of cluster analysis on genetic markers to identify genetic-based subgroups while taking into account possible confounding by population stratification. We show that it is highly relevant to consider the confounding nature of population stratification in order to avoid that detected clusters are strongly related to population groups instead of disease-specific groups. Therefore, we explain the use of principal components to correct for population stratification while clustering affected individuals into genetic-based subgroups. The principal components are obtained using 30 ancestry informative markers (AIM), and the first two PCs are determined to discriminate between continental origins of the affected individuals. Genotypes on 51 CD associated single nucleotide polymorphisms (SNPs) are used to perform latent class analysis, hierarchical and Partitioning Around Medoids (PAM) cluster analysis within a sample of affected individuals with and without the use of principal components to adjust for population stratification. It is seen that without correction for population stratification clusters seem to be influenced by population stratification while with correction clusters are unrelated to continental origin of individuals. 相似文献
3.
4.
Emmanuelle Fontoura José Darival Ferreira Jamile Bubadué Ana Maria Ribeiro Leonardo Kerber 《Journal of morphology》2020,281(10):1223-1240
A diverse fossil record of Cervidae (Mammalia) has been documented in the South American Pleistocene, when these animals arrived during the Great American Biotic Interchange. Using computed tomography-scanning techniques, it is possible to access the endocranial morphology of extinct species. Here, we studied the brain endocast of the extinct late Pleistocene cervid Antifer ensenadensis from southern Brazil, one of the largest forms that lived on this continent, using comparative morphology, geometric morphometrics, and encephalization quotients. The analyzed endocasts demonstrate that A. ensenadensis had a gyrencephalic brain, showing a prominent longitudinal sinus (=sagittal superior sinus), which is also observed in the large South American cervid Blastocerus dichotomus. The encephalization quotient is within the variation of extant cervids, suggesting maintenance of the pattern of encephalization from at least the late Pleistocene. Geometric morphometric analysis suggested a clear and linear allometric trend between brain endocast size and shape, and highlights A. ensenadensis as an extreme form within the analyzed cervids regarding brain morphology. 相似文献
5.
A predominant idiotype on rabbit anti-VH a1 allotype antibodies: sharing by both major and minor VH subgroups 总被引:2,自引:0,他引:2
In every rabbit examined, greater than or equal to 80% of antibodies directed against the VH allotypic marker, a1, bears a predominant idiotype (IdX-a1). The IdX-a1 marker is site-associated and expressed on H chains, but not L chains, of anti-a1 antibody. Experiments using rabbits suppressed for the VH a subgroup demonstrated that IdX-a1 can be associated with both major (a+) and minor (a-) VH subgroup gene products and that a1 rabbits contain IdX-a1 within their genetic repertoire. The genetic and regulatory implications of our results are discussed. 相似文献
6.
7.
C-Glycosylflavonoids. The chemistry of aspalathin 总被引:1,自引:0,他引:1
1. The isolation of aspalathin, the principal phenolic constituent in the leaves of Aspalathus linearis, is described and its properties are discussed. 2. The compound has been identified as 3'-C-beta-d-glucopyranosyl-2',3,4,4',6'-pentahydroxydihydrochalcone by the preparation and analysis of various derivatives, by photochemical oxidation to 2,3-dihydroiso-orientin and by nuclear-magnetic-resonance studies. 相似文献
8.
P Navarro-Rosinés C Roux A Bellemère 《Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie》2001,324(5):443-451
An ultrastructural study of Weddellomyces epicallopisma (ascomata wall, asci, ascospores and vegetative hyphae), the first done on the family Dacampiaceae, confirms most of the observations made in light microscopy. Moreover it shows that ascospores are provided with an endospore (not visible in light microscope) and that the structure of the ascospore septum is more complex. The similarity of the wall structure between the ascospore and the hyphoid appendages, developed on the upper part of the ascoma, is emphasized. 相似文献
9.
Phytochrome-mediated germination of fern spores of Dryopteris paleacea Sw. was initiated by a saturating red-light (R) irradiation after 20 h of imbibition. For its realization external Ca2+ was required, with a threshold at a submicromolar concentration, and an optimum was reached around 10-4 M. At concentrations 10-1 M only a reduced response was obtained, based probably on an unspecific osmotic or ionic effect. The germination response was inhibited by La3+, an antagonist of Ca2+. From these results it is concluded that Ca2+ influx from the medium into the spores may be an important event in phytochrome-mediated germination. In the absence of Ca2+ the R-stimulated system remained capable of responding to Ca2+, added as late as 40 h after R. Moreover, Ca2+ was effective even if added after the active form of phytochrome, Pfr, had been abolished by far-red (FR) 24 h after R. Thus, the primary effect of Pfr, that initiates the transduction chain, does not require calcium. Coupling of Pfr to subsequent dark reactions has been investigated by R-FR irradiations with various dark intervals. The resulting escape kinetics were characterized by a lag phase (6 h) and half-maximal escape from FR reversibility (19 h). These kinetics were not significantly changed by the presence or absence of calcium. Thus, direct interaction of Pfr and calcium is not a step in the transduction chain initiated by the active form of photochrome.Abbreviations EGTA
ethyleneglycol-bis(-aminoethyl ether)-N,N,N,N-tetraacetic acid
- FR
far-red light
- Pr
red-light-absorbing form of phytochrome
- Pfr
far red-light-absorbing form of phytochrome
- Pipes
piperazine-1,4-bis(2-ethanesulfonic acid)
- R
red light
A preliminary report of this work was presented at the XIV Int. Bot. Congr., Berlin (West), Germany, Book of Abstracts, 2-116a-5 (1987) 相似文献
10.
Nucleotide sequence of 10 kilobases of rat tyrosine aminotransferase gene 5'' flanking region. 总被引:5,自引:3,他引:2
J Oddos T Grange K D Carr B Matthews J Roux H Richard-Foy R Pictet 《Nucleic acids research》1989,17(21):8877-8878