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Mohammadi-Noori Ehsan Salehi Nahid Mozafari Hadi Elieh Ali Komi Daniel Saidi Mohammadrza Bahrehmand Fariborz Vaisi-Raygani Asad Elahirad Saeed Moini Ali Kiani Amir 《Molecular biology reports》2020,47(3):1809-1820
Molecular Biology Reports - Fetuin-A (AHSG) is a multifunctional secretory protein and acts as an ectopic valve and artery calcification inhibitor. We assessed the correlation between serum levels... 相似文献
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Sanaz Naghavi Alhosseini Fathollah Moztarzadeh Akbar Karkhaneh Masumeh Dodel Mahsa Khalili Tarlan Eslami Arshaghi Elnaz Elahirad Masoud Mozafari 《Journal of cellular physiology》2019,234(9):15279-15287
Neuroregeneration strategies involve multiple factors to stimulate nerve regeneration. Neural support with chemical and physical cues to optimize neural growth and replacing the lesion neuron and axons are crucial for designing neural scaffolds, which is a promising treatment approach. In this study, polypyrrole polymerization and its functionalization at the interface developed by glycine and gelatin for further optimization of cellular response. Nanofibrous scaffolds were fabricated by electrospinning of polyvinyl alcohol and chitosan solutions. The electrospun scaffolds were polymerized on the surface by pyrrole monomers to form an electroactive interface for further applications in neural tissue engineering. The polymerized polypyrrole showed a positive zeta potential value of 57.5 ± 5.46 mV. The in vitro and in vivo biocompatibility of the glycine and gelatin-functionalized polypyrrole-coated scaffolds were evaluated. No inflammatory cells were observed for the implanted scaffolds. Further, DAPI nucleus staining showed a superior cell attachment on the gelatin-functionalized polypyrrole-coated scaffolds. The topography and tuned positively charged polypyrrole interface with gelatin functionalization is expected to be particularly efficient physical and chemical simultaneous factors for promoting neural cell adhesion. 相似文献
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