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1.
Published gene frequency data, checked for consistency of allele definitions across laboratories and for comparability of
geographically identical samples, were pooled into a data set containing frequencies at nine loci for each of 20 populations
that encompassed 10 macaque species. Genetic distances were calculated by the methods of Kidd and Cavalli-Sforza (1974). These
distances were used to construct phylogenetic trees and to evaluate the relationships between divergence times and effective
population sizes. Inter-and intraspecific genetic distances and the groupings defined by phenetic tree analyses support Fooden’s
(1976) classification of the genus Macacainto four species groups. A paleozoogeographical model of Asia including the known times of major sea-level changes allows
us to explain Macacainto four species groups. A paleozoogeographical model of Asia including the known times of major sea-level changes allows
us to explain qualitatively the inferred evolutionary relationships among macaque species. Many assumptions are required in
order to estimate the variables necessary in the quantitative prediction of genetic differences for a comparison between any
two populations. Examination of those assumptions demonstrates the need for more accurate genetic as well as paleozoogeographic
information.
An erratum to this article is available at . 相似文献
2.
3.
Don Trinh Nguyen Jens Christian G?pfert Nobuhiro Ikezawa Gillian MacNevin Meena Kathiresan Jürgen Conrad Otmar Spring Dae-Kyun Ro 《The Journal of biological chemistry》2010,285(22):16588-16598
Sesquiterpene lactones are characteristic natural products in Asteraceae, which constitutes ∼8% of all plant species. Despite their physiological and pharmaceutical importance, the biochemistry and evolution of sesquiterpene lactones remain unexplored. Here we show that germacrene A oxidase (GAO), evolutionarily conserved in all major subfamilies of Asteraceae, catalyzes three consecutive oxidations of germacrene A to yield germacrene A acid. Furthermore, it is also capable of oxidizing non-natural substrate amorphadiene. Co-expression of lettuce GAO with germacrene synthase in engineered yeast synthesized aberrant products, costic acids and ilicic acid, in an acidic condition. However, cultivation in a neutral condition allowed the de novo synthesis of a single novel compound that was identified as germacrene A acid by gas and liquid chromatography and NMR analyses. To trace the evolutionary lineage of GAO in Asteraceae, homologous genes were further isolated from the representative species of three major subfamilies of Asteraceae (sunflower, chicory, and costus from Asteroideae, Cichorioideae, and Carduoideae, respectively) and also from the phylogenetically basal species, Barnadesia spinosa, from Barnadesioideae. The recombinant GAOs from these genes clearly showed germacrene A oxidase activities, suggesting that GAO activity is widely conserved in Asteraceae including the basal lineage. All GAOs could catalyze the three-step oxidation of non-natural substrate amorphadiene to artemisinic acid, whereas amorphadiene oxidase diverged from GAO displayed negligible activity for germacrene A oxidation. The observed amorphadiene oxidase activity in GAOs suggests that the catalytic plasticity is embedded in ancestral GAO enzymes that may contribute to the chemical and catalytic diversity in nature. 相似文献
4.
Don Ross 《Biology & philosophy》2012,27(2):287-297
The revised edition of Paul Seabright’s The Company of Strangers is critically reviewed. Seabright aims to help non-economists participating in the cross-disciplinary study of the evolution
of human sociality appreciate the potential value that can be added by economists. Though the book includes nicely constructed
and vivid essays on a range of economic topics, in its main ambition it largely falls short. The most serious problem is endorsement
of the so-called strong reciprocity hypothesis that has been promoted by several prominent economists, but does not pass muster
with biologists. 相似文献
5.
6.
Rosa Agudo Ciro Rico Carles Vilà Fernando Hiraldo José Antonio Donázar 《BMC evolutionary biology》2010,10(1):384
Background
Anthropogenic habitat modifications have led to the extinction of many species and have favoured the expansion of others. Nonetheless, the possible role of humans as a diversifying force in vertebrate evolution has rarely been considered, especially for species with long generation times. We examine the influence that humans have had on the colonization and phenotypic and genetic differentiation of an insular population of a long-lived raptor species, the Egyptian vulture (Neophron percnopterus). 相似文献7.
Carles Grau Romuald Ginhoux Alejandro Riera Thanh Lam Nguyen Hubert Chauvat Michel Berg Julià L. Amengual Alvaro Pascual-Leone Giulio Ruffini 《PloS one》2014,9(8)
Human sensory and motor systems provide the natural means for the exchange of information between individuals, and, hence, the basis for human civilization. The recent development of brain-computer interfaces (BCI) has provided an important element for the creation of brain-to-brain communication systems, and precise brain stimulation techniques are now available for the realization of non-invasive computer-brain interfaces (CBI). These technologies, BCI and CBI, can be combined to realize the vision of non-invasive, computer-mediated brain-to-brain (B2B) communication between subjects (hyperinteraction). Here we demonstrate the conscious transmission of information between human brains through the intact scalp and without intervention of motor or peripheral sensory systems. Pseudo-random binary streams encoding words were transmitted between the minds of emitter and receiver subjects separated by great distances, representing the realization of the first human brain-to-brain interface. In a series of experiments, we established internet-mediated B2B communication by combining a BCI based on voluntary motor imagery-controlled electroencephalographic (EEG) changes with a CBI inducing the conscious perception of phosphenes (light flashes) through neuronavigated, robotized transcranial magnetic stimulation (TMS), with special care taken to block sensory (tactile, visual or auditory) cues. Our results provide a critical proof-of-principle demonstration for the development of conscious B2B communication technologies. More fully developed, related implementations will open new research venues in cognitive, social and clinical neuroscience and the scientific study of consciousness. We envision that hyperinteraction technologies will eventually have a profound impact on the social structure of our civilization and raise important ethical issues. 相似文献
8.
Elicitation of Necrosis in Vigna unguiculata Walp. by Homogeneous Aspergillus niger Endo-Polygalacturonase and by alpha-d-Galacturonate Oligomers
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Endo-polygalacturonase (PG) was purified from a commercial preparation of Aspergillus niger pectinase by means of carboxymethylcellulose chromatography, preparative isoelectric focusing, and gel permeation through Sephadex G-50. The enzyme was electrophoretically homogeneous and consisted of a single polypeptide chain with a molecular weight of 33,500. The enzyme exhibited a specific activity significantly higher than those of purified polygalacturonases from phytopathogenic fungi. Galacturonate oligomers with a degree of polymerization higher than four appeared quickly as products of the enzymic hydrolysis of Napolygalacturonate. The oligomers were later degraded to di- and monogalacturonate. The homogeneous enzyme and growing mycelium of Aspergillus niger separately elicited a necrotic response in cowpea (Vigna unguiculata Walp.) pods. Heat-inactivated PG and PG inactivated with specific antibodies did not elicit necrosis, suggesting that the catalytic activity of the enzyme is necessary for its function as an elicitor. The PG-released oligosaccharides from Vigna cell wall and the galacturonides with a degree of polymerization greater than four separately elicited necrosis, whereas di- and monogalacturonate did not. 相似文献
9.
Caminal G Lafuente J López-Santín J Poch M Solà C 《Biotechnology and bioengineering》1987,29(3):366-369
A recursive estimation scheme, the Extended Kalman Filter (EKF) technique, was applied to study enzymatic deactivation in the enzymatic hydrolysis of pretreated cellulose using a model previously developed by the authors. When no deactivation model was assumed, the results showed no variation with time for all the model parameters except for the maximum rate of cellobiose-to-glucose conversion (r'(m)).The r'(m) variation occurred in two zones with a grace period. A new model of enzymatic hydrolysis of pretreated cellulose deactivation was proposed and validated showing better behavior than the old deactivation model. This approach allows one to study enzyme deactivation without additional experiments and within operational conditions. 相似文献
10.
Mathematical modelization of a packed-bed reactor performance with immobilized yeast for ethanol fermentation 总被引:1,自引:0,他引:1
The performance of a continuous vertical packed-bed reactor with yeast immobilized in carrageenan gel beads is reported. The study focuses on the mathematical modelling of the steady-state fermentor behavior by means of a tanks-in-series model which includes the intrinsic kinetic model and the external mass transfer and internal diffusion-reaction conditions in the beads. 相似文献