排序方式: 共有3条查询结果,搜索用时 15 毫秒
1
1.
Rizky Abdulah Herlambang Noerjasin Leri Septiani Mutakin Irma R. Defi Eka W. Suradji Irma M. Puspitasari Melisa I. Barliana Chiho Yamazaki Minato Nakazawa Hiroshi Koyama 《Biological trace element research》2013,154(1):1-6
Selenium is an essential nutrient for human health, and maternal selenium concentration has been reported to be associated with pregnancy outcome. To further investigate the possible role of selenium (Se) in miscarriage, we conducted a case–control study to evaluate the correlations among selenium status, glutathione peroxidase activity, and spontaneous abortion. A total of 46 subjects with normal pregnancies and 25 subjects with spontaneous abortion were recruited, and their serum selenium concentrations and serum glutathione peroxidase activities were analyzed. The total serum selenium concentrations in subjects with normal pregnancies were significantly higher than those of subjects with spontaneous abortion; however, the glutathione peroxidase activities were similar in both groups. We further separated the subjects into smoking and nonsmoking groups, and the logistic regression analysis suggested that total serum selenium concentration, but not serum glutathione peroxidase activity or smoking, was significantly correlated with the incidence of miscarriage. The present study thus reaffirms that low serum selenium levels are associated with miscarriage and that selenium plays an important role in pregnancy maintenance. 相似文献
2.
Defi IR Yamazaki C Kameo S Kobayashi K Nakazawa M Shinya Y Sato N Wada N Shirakura K Koyama H 《Biological trace element research》2011,144(1-3):388-395
Several studies show the consistent results of the decrease in plasma or serum selenium (Se) after surgery, and the change is suggested to be a negative acute phase response of Se to the surgical inflammation. Plasma glutathione peroxidase (GPx), which is included in the acute phase response proteins, is a selenoenzyme. However, previous studies failed to show any changes in GPx activity before and after surgery. In the present study, we investigated the Se- and selenoenzyme responses that accompany the acute inflammatory reactions during and following major surgery. Patients who underwent elective total knee arthroplasty surgery due to knee osteoarthritis at the Department of Orthopaedic Surgery at Gunma University Hospital in Japan were studied. The plasma Se concentration was determined, and the activity of plasma GPx was measured. C-reactive protein (CRP), albumin, blood urea nitrogen (BUN), and white blood cell (WBC) count were also analysed. Increases in the inflammatory biomarkers of CRP and WBC showed inflammatory reactions with the surgery. A significant increase in plasma GPx activity (p?0.05) and decreases in the plasma Se concentration (p?0.05) and in serum albumin (p?0.05) after surgery were observed. Since albumin is a Se-containing protein and represents a negative acute phase protein that provides amino acids for the production of other series of acute phase proteins, the present results suggest that there is a redistribution of plasma Se to GPx that occurs as an acute phase response, and the source of Se for GPx could be, at least partly, from albumin. 相似文献
3.
Abdulah Rizky herlambang Herlambang Septiani Leri Mutakin Defi Irma R. Suradji Eka W. Puspitasari Irma M. Barliana Melisa I. Yamazaki Chiho Nakazawa Minato Koyama Hiroshi 《Biological trace element research》2019,190(1):282-282
Biological Trace Element Research - The original version of this article unfortunately contained a mistake. The name of “Herlambang herlambang” is now corrected in the author group of... 相似文献
1