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1.
A new case of Robertsonian translocation in cattle 总被引:1,自引:0,他引:1
H M Berland A Sharma E P Cribiu R Darre J Boscher C P Popescu 《The Journal of heredity》1988,79(1):33-36
A new Robertsonian translocation was found in several animals of the Blonde d'Aquitaine breed. The fused chromosome analyzed by G- and R-banding results from the fusion of chromosomes 21 and 27. C-banding suggests that the fused chromosome is dicentric. 相似文献
2.
L. Ferretti B. G. D. Urquhart A. Eggen I. Olsaker B. Harlizius B. Castiglioni A. Mezzelani S. Solinas Toldo U. Thieven Y. Zhang A. L. G. Morgan V. M. Teres M. Schwerin I. Martin-Burriel B. P. Chowdhary G. Erhardt I. J. Nijman E. P. Cribiu W. Barendse H. Leveziel R. Fries J. L. Williams 《Mammalian genome》1997,8(1):29-36
The mapping strategy for the bovine genome described in this paper uses large insert clones as a tool for physical mapping
and as a source of highly polymorphic microsatellites for genetic typing, and was one objective of the BovMap Project funded
by the European Union (UE). Eight-three cosmid and phage clones were characterized and used to physically anchor the linkage
groups defining all the bovine autosomes and the X Chromosome (Chr). By combining physical and genetic mapping, clones described
in this paper have led to the identification of the linkage groups corresponding to Chr 9, 12, 16, and 25. In addition, anchored
loci from this study were used to orient the linkage groups corresponding to Chr 3, 7, 8, 9, 13, 16, 18, 19, and 28 as identified
in previously published maps. Comparison of the estimated size of the physical and linkage maps suggests that the genetic
length of the bovine genome may be around 4000 cM.
Received: 1 July 1996 / Accepted: 13 September 1996 相似文献
3.
A. Schmitz A. Oustry B. Chaput I. Bahri-Darwich M. Yerle D. Millan G. Frelat E. P. Cribiu 《Mammalian genome》1995,6(6):415-420
A bovine bivariate flow karyotype has been established from a primary fibroblast cell culture carrying a 4;10 Robertsonian translocation. From 27 to 36 populations could be resolved by flow cytometry although the anticipated number was 31. Separation of chromosomal pairs into two populations explains this high resolution and confirms the high level of heteromorphism previously observed. We used a PARM-PCR (Priming Autorizing Random Mismatches) procedure for the production of paint probes from flow-sorted chromosome fractions. These probes were used for chromosome identification by fluorescence in situ hybridization (FISH) on R-banded metaphase spreads. We present the localization of all the bovine chromosome types on the flow karyotype. Twenty-two chromosome types including the translocated chromosome were sorted as pure fractions. 相似文献
4.
Annemarie MM Vlaar Angela EP Bouwmans Marinus JPG van Kroonenburgh Werner H Mess Selma C Tromp Piet GWM Wuisman Alfons GH Kessels Ania Winogrodzka Wim EJ Weber 《BMC neurology》2007,7(1):28
Background
Parkinson's disease (PD) is the second most common neurodegenerative disorder. As there is no definitive diagnostic test, its diagnosis is based on clinical criteria. Recently transcranial duplex scanning (TCD) of the substantia nigra in the brainstem has been proposed as an instrument to diagnose PD. We and others have found that TCD scanning of substantia nigra duplex is a relatively accurate diagnostic instrument in patients with parkinsonian symptoms. However, all studies on TCD so far have involved well-defined, later-stage PD patients, which will obviously lead to an overestimate of the diagnostic accuracy of TCD. 相似文献5.
6.
Philippe Pinton Laurent Schibler Edmond Cribiu Joel Gellin Martine Yerle 《Mammalian genome》2000,11(4):306-315
In total, 113 genes that have already been located in humans and goats were cytogenetically mapped in pigs. For this purpose,
165 gene-containing bacterial artificial chromosomes (BACs) isolated in goats were used in heterologous fluorescent in situ
hybridization on porcine chromosomes. Among them, 113 (or 69%) gave clear and specific signals, and 52 did not work in heterologous
conditions. These localizations are a significant contribution to development of the porcine gene map and also to the comparative
map for humans and pigs. They allowed us to specify the information obtained by Zoo-FISH while taking the gene order into
account; the number of conserved fragments detected for human and pig chromosomes reached 84. The average size of conserved
fragments could be estimated at 33 cM. As these genes had already been mapped in goats, the comparison was extended to ruminants.
The previous results obtained in this species, suggesting a correlation between human chromosome abnormalities and evolutionary
breakpoints, were confirmed in pigs.
Received: 22 July 1999 / Accepted: 3 December 1999 相似文献
7.
Sophie Godard Laurent Schibler Anne Oustry Edmond P. Cribiu Gérard Guérin 《Mammalian genome》1998,9(8):633-637
A horse BAC library was constructed with about 40, 000 clones and mean insert size of 110 kb representing a 1.5 genome equivalent
coverage and a probability of finding a single sequence of 0.75. It was characterized by PCR screening of about 130 sequences
of horse microsatellites and exonic gene sequences retrieved from databases. BACs containing 8 microsatellites and 12 genes
were subsequently localized by fluorescent in situ hybridization (FISH) on chromosomes. Two linkage groups were newly assigned
to chromosomes: LG2 to ECA3 and LG5 to ECA24, and five linkage groups were also oriented—LG3, LG4, LG5, LG8, and LG12—leaving
only three groups unassigned. This work showed how this library makes an integrated map a realistic objective for the near
future and how it can make comparative mapping more efficient in a search for candidate genes of interest.
Received: 9 January 1998 / Accepted: 13 April 1998 相似文献
8.
A genetic and physical map of bovine Chromosome 11 总被引:3,自引:0,他引:3
D. Vaiman D. Mercier A. Eggen I. Bahri-Darwich C. Grohs E. P. Cribiu G. Dolf A. Oustry G. Guérin H. Levéziel 《Mammalian genome》1994,5(9):553-556
A genetic map of bovine Chromosome (Chr) 11 (BTA11, synteny group U16) has been constructed from 330 animals belonging to 21 families, which constitute the international bovine reference panel (IBRP). This map is based on 13 polymorphic microsatellite markers, two of which were chosen in previously published maps. Three markers have been isolated from cosmids. Two of the three cosmids have been physically localized by fluorescence in situ hybridization (FISH), to anchor the genetic map on the chromosome. In addition, a biallelic polymorphism in the -lactoglobulin gene (LGB) has been genetically positioned relative to the microsatellite markers. The most probable order of the markers is: cen-INRA044-BM716-INRA177-(TGLA 327, INRA198, INRA131)-INRA111-INRABERN169-(INRA115, INRA032)-INRA108-INRABERN162-INRA195-LGB. T The total linkage group spans 126 cM, which probably corresponds to most of the chromosome length. The average intermarker distance is about 10.5 cM, allowing the potential detection of a genetic linkage with any Economic Trait Loci (ETL) of this chromosome. 相似文献
9.
10.