排序方式: 共有7条查询结果,搜索用时 15 毫秒
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Kheng Chheng Michael J. Carter Kate Emary Ngoun Chanpheaktra Catrin E. Moore Nicole Stoesser Hor Putchhat Soeng Sona Sin Reaksmey Paul Kitsutani Borann Sar H. Rogier van Doorn Nguyen Hanh Uyen Le Van Tan Daniel Paris Stuart D. Blacksell Premjit Amornchai Vanaporn Wuthiekanun Christopher M. Parry Nicholas P. J. Day Varun Kumar 《PloS one》2013,8(4)
BackgroundFebrile illnesses are pre-eminent contributors to morbidity and mortality among children in South-East Asia but the causes are poorly understood. We determined the causes of fever in children hospitalised in Siem Reap province, Cambodia.ConclusionWe identified a microbiological cause of fever in almost 50% of episodes in this large study of community-acquired febrile illness in hospitalized children in Cambodia. The range of pathogens, antimicrobial susceptibility, and co-morbidities associated with mortality described will be of use in the development of rational guidelines for infectious disease treatment and control in Cambodia and South-East Asia. 相似文献
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Kheng Chheng Sarah Tarquinio Vanaporn Wuthiekanun Lina Sin Janjira Thaipadungpanit Premjit Amornchai Ngoun Chanpheaktra Sarinna Tumapa Hor Putchhat Nicholas P. J. Day Sharon J. Peacock 《PloS one》2009,4(8)
Background
The incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection is rising in the developed world but appears to be rare in developing countries. One explanation for this difference is that resource poor countries lack the diagnostic microbiology facilities necessary to detect the presence of CA-MRSA carriage and infection.Methodology and Principal Findings
We developed diagnostic microbiology capabilities at the Angkor Hospital for Children, Siem Reap, western Cambodia in January 2006 and in the same month identified a child with severe community-acquired impetigo caused by CA-MRSA. A study was undertaken to identify and describe additional cases presenting between January 2006 and December 2007. Bacterial isolates underwent molecular characterization using multilocus sequence typing, staphylococcal cassette chromosome mec (SCCmec) typing, and PCR for the presence of the genes encoding Panton-Valentine Leukocidin (PVL). Seventeen children were identified with CA-MRSA infection, of which 11 had skin and soft tissue infection and 6 had invasive disease. The majority of cases were unrelated in time or place. Molecular characterization identified two independent MRSA clones; fifteen isolates were sequence type (ST) 834, SCCmec type IV, PVL gene-negative, and two isolates were ST 121, SCCmec type V, PVL gene-positive.Conclusions
This represents the first ever report of MRSA in Cambodia, spread of which would pose a significant threat to public health. The finding that cases were mostly unrelated in time or place suggests that these were sporadic infections in persons who were CA-MRSA carriers or contacts of carriers, rather than arising in the context of an outbreak. 相似文献4.
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Thomas Pool Vittoria Elliott Gordon Holtgrieve Mauricio Arias Irit Altman Leslie Kaufman Kevin McCann Evan D. G. Fraser Loïc Tudesque Mathieu Chevalier Gael Grenouillet Ratha Chea Sovan Lek Bailey McMeans Michael Cooperman Chheng Phen Lee Hannah Ben Miller Chuanbo Guo So Nam 《Freshwater Biology》2019,64(11):2026-2036
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Ellen E. Biesack Binh T. Dang Amanda S. Ackiss Christopher E. Bird Phen Chheng Latsamy Phounvisouk Oanh T. Truong Kent E. Carpenter 《Journal of fish biology》2020,97(3):696-707
Impacts of urban development on aquatic populations are often complex and difficult to ascertain, but population genetic analysis has allowed researchers to monitor and estimate gene flow in the context of existing and future hydroelectric projects. The Lower Mekong Basin is undergoing rapid hydroelectric development with around 50 completed and under-construction dams and 95 planned dams. The authors investigated the baseline genetic diversity of two exploited migratory fishes, the mud carp Henicorhynchus lobatus (five locations), and the rat-faced pangasiid catfish, Helicophagus leptorhynchus (two locations), in the Lower Mekong Basin using the genomic double digest restriction site-associated DNA (ddRAD) sequencing method. In both species, fish sampled upstream of Khone Falls were differentiated from those collected at other sites, and Ne estimates at the site above the falls were lower than those at other sites. This was the first study to utilize thousands of RAD-generated single nucleotide polymorphisms to indicate that the Mekong's Khone Falls are a potential barrier to gene flow for these two moderately migratory species. The recent completion of the Don Sahong dam across one of the only channels for migratory fishes through Khone Falls may further exacerbate signatures of isolation and continue to disrupt the migration patterns of regionally vital food fishes. In addition, H. lobatus populations downstream of Khone Falls, including the 3S Basin and Tonle Sap system, displayed robust connectivity. Potential obstruction of migration pathways between these river systems resulting from future dam construction may limit dispersal, which has led to elevated inbreeding rates and even local extirpation in other fragmented riverine species. 相似文献
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Vittoria L. Elliott Phen Chheng Sophorn Uy Gordon W. Holtgrieve 《Journal of fish biology》2019,94(6):1019-1025
Tropical freshwater ecosystems are some of the world's most biodiverse and productive systems where determining what sustainable exploitation of inland fisheries looks like is particularly challenging. One of the greatest obstacles to sustainable management is collecting and using quality data on fish production and yield. The biodiversity and hydro-ecology of these systems often under open-access governance, add to the complexity of managing them. This paper describes an integrated citizen-science, earth observation, environmental DNA and independent survey approach to collecting fish and fisheries data, using the Cambodian Mekong as a case study. 相似文献
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