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1.
Context-specific calls, which have a distinct acoustic structure and are selectively produced in specific contexts, are a prerequisite for calls that function referentially. Functionally referential calls, which convey information to conspecifics about objects and events in the external world, have been found in a number of species, notably primates. Evidence of context-specific calls in apes, however, is largely absent. We analysed whether the barks of wild male chimpanzees in the Ta? Forest, Côte d'Ivoire, are context specific. We examined the acoustic structure of barks, and other calls produced in association with barks, in six contexts, using discriminant function analysis. Chimpanzees produced context-specific signals in two ways. First, they produced two acoustically graded bark subtypes, in hunt and snake contexts, respectively. Second, they produced context-specific signal combinations of barks with acoustically different call types or drums. These signal combinations increased specificity levels in three of the six contexts to over 90%, a level similar to the classic vervet monkey, Cercophithecus aethiops, predator alarm calls. Furthermore, specific chimpanzee signals were produced in contexts other than alarm, such as travel and hunting, where the potential benefits of evolving specific calls are less obvious. These signals may convey specific context information to listeners, and thus function referentially; however, to confirm this, analyses of listeners' responses are required. The results show that two strategies for producing context-specific signals seem to have evolved in a species other than humans: chimpanzees produce context-specific bark subtypes and context-specific signal combinations. Copyright 2003 Published by Elsevier Science Ltd on behalf of The Association for the Study of Animal Behaviour. 相似文献
2.
James F. Richards Kulgite Lit Roland Fuca Catherine Bourgeault 《Biochemical and biophysical research communications》1981,99(4):1461-1467
Several species of ornithine decarboxylase were separated by chromatography of rat thymus and kidney extracts on DEAE-Sepharose CL-6B. One major and one minor species were absent from thymus of rats two hours after hormone treatment but otherwise, the elution profile was identical to thymus from control animals. The elution patterns of ODC activity in kidneys of rats treated 2.5 or 5 hours before sacrifice with dexamethasone differ from that of control kidney and from each other. Enzyme from kidneys early after hormone treatment is eluted earlier than enzyme from control tissue, while at 5 hours, the enzyme is eluted much later than in the control. This suggests that the hormone-induced activity is subsequently modified. 相似文献
3.
Natalia Ermak Bernard Lacour Françoise Goirand Stéphanie Vicca 《Biochemical and biophysical research communications》2010,393(4):783-787
We compared the apoptotic mechanism involved in U937 human monocytic cell line in presence of oxidized low-density lipoproteins (oxLDL) obtained after treatment with hypochlorous acid (HOCl) or copper (Cu).Both types of oxLDL induced U937 apoptotic cell death via the mitochondrial pathway. In contrast to HOCl-oxLDL, Cu-oxLDL induced apoptosis via a caspase-independent mechanism, with no activation of pro-caspase-3, but via the release of apoptosis inducing factor (AIF) from mitochondria.The apoptotic program of the monocyte differs depending on the mode of LDL oxidation, based on differences in the oxidatively modified components of the two oxLDL types. 相似文献
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Jo-Anne M.D. Murray Catherine Dunnett Meriel J.S. Moore-Colyer Annette C. Longland 《Animal Feed Science and Technology》2012,171(2-4):192-204
A series of in vitro experiments were conducted to assess three fibrolytic enzyme preparations as potential feed additives in equine diets. The three fibrolytic enzyme preparations were a concentrated cellulase (E1), an acid cellulase (E2) and a concentrated xylanase (E3). The enzymes were evaluated on their ability to modify the cell wall fraction of high-temperature dried lucerne (HTL) under various experimental conditions including differences in temperature, pH, incubation period, substrate levels and particle size to enable selection of the enzyme preparation most effective in the hydrolysis of lucerne. Results showed enzyme activities (as measured by reducing sugar assays) to be greatest at 50 °C, pH 5 and over an incubation period of greater than 20 h. E1 exhibited the greatest effect on total monosaccharide release from the HTL compared to E2 and E3. Moreover, dry matter (DM) and total non-starch polysaccharide (TNSP) losses were also greater in HTL treated with E1 compared to E2 and E3. Therefore, since the cell wall fraction of HTL contained substantial amounts of cellulose, the enzyme with the highest cellulase activity (Enzyme 1) was most effective in hydrolysing the cell walls of HTL. Consequently, it would appear that the application of exogenous fibrolytic enzyme preparations to forages requires the chemical characterisation of the target forage to enable selection of enzymes that are (a) most suitable to degrade the cell wall components of the candidate forage and (b) effective under field conditions. 相似文献
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Bernard Appiah 《CMAJ》2012,184(16):E831-E832
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The recurrence of influenza A epidemics has originally been explained by a “continuous antigenic drift” scenario. Recently, it has been shown that if genetic drift is gradual, the evolution of influenza A main antigen, the haemagglutinin, is punctuated. As a consequence, it has been suggested that influenza A dynamics at the population level should be approximated by a serial model. Here, simple models are used to test whether a serial model requires gradual antigenic drift within groups of strains with the same antigenic properties (antigenic clusters). We compare the effect of status based and history based frameworks and the influence of reduced susceptibility and infectivity assumptions on the transient dynamics of antigenic clusters. Our results reveal that the replacement of a resident antigenic cluster by a mutant cluster, as observed in data, is reproduced only by the status based model integrating the reduced infectivity assumption. This combination of assumptions is useful to overcome the otherwise extremely high model dimensionality of models incorporating many strains, but relies on a biological hypothesis not obviously satisfied. Our findings finally suggest the dynamical importance of gradual antigenic drift even in the presence of punctuated immune escape. A more regular renewal of susceptible pool than the one implemented in a serial model should be part of a minimal theory for influenza at the population level. 相似文献
10.
E. Backe G. Lotz U. Tittelbach H. Thurmer E. Gierke N. Kersten A. Bernard G. Wallenstein W. D. Schneider 《Biomarkers》2000,5(2):119-128
The inflammation markers alpha-1-antitrypsin (AAT), Clara cell protein (CC-16), soluble interleukin-2-receptor (IL-R) and the soluble adhesion molecule E-selectin, the intercellular adhesion molecule (ICAM-1) and the vascular adhesion molecule (VCAM-1) were determined in the serum of 195 salt-exposed miners to analyse dose-response relationships between markers and potash dust. Alpha-1-antitrypsin, Clara-cell protein, IL2-R, E-selectin and VCAM-1 were not changed by salt exposure, however the ICAM-1 level in the serum fell slightly as the salt exposure increased. This effect was strongest in the group of smokers, still visible in the group of ex-smokers, no effect was seen in non-smokers. Markers, with the exception of VCAM-1, were influenced by tobacco exposure. Since markers were not elevated in relation to salt dust exposure, the results do not support an inflammatory effect of potash dust on the respiratory system. 相似文献