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排序方式: 共有100条查询结果,搜索用时 31 毫秒
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Rhida M'Rad Marek Sanak Georges Deschenes Jing Zhou Catherine Bonaiti-Pellie Laurent Holvoet-Vermaut Solange Heuertz Marie-Claire Gubler Michel Broyer Jean-Pierre Grunfeld Karl Tryggvason Marie-Claude Hors-Cayla 《Human genetics》1992,90(4):420-426
Thirty one families with Alport syndrome including 3 families with associated syndromes were studied. The location of the COL4A5 gene, responsible for the Alport syndrome, was determined by linkage analysis with eight probes of the Xq arm and by a radiation hybrid panel. Concordant data indicated the localization of the Alport gene between DXS17 and DXS11. Four deletions and one single base mutation of the COL4A5 gene were detected. Homogeneity tests failed to show any evidence of genetic heterogeneity superimposed on clinical heterogeneity for ophthalmic signs and end-stage renal disease age. 相似文献
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Vicente Gomes Phan Van Ngan Claude de Broyer Maria José deA. C. Rocha Passos 《Hydrobiologia》1993,262(2):109-113
Mitotic and meiotic chromosomes of the Antarctic lysianassoid amphipod Waldeckia obesa are described. The modal chromosome number is n = 25 and 2n = 50. The potential applications of cytogenetical studies in this group are discussed. 相似文献
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Joël Broyer 《Bird Study》2013,60(2):141-150
Capsule Mowing postponement in 25% of a meadow system may lead to improved but instable population dynamics in meadow birds. Aim To monitor the long‐term effects of mowing postponement on the abundance and territory density of meadow passerines in 25% of a 3000‐ha hay‐meadow area in the Saône Valley (eastern France). Methods From 1993 to 2009, passerine abundance was measured annually in 78 plots using point counts and territory density was assessed in two study areas by Territory Mapping. Results The programme of mowing postponement led to substantially increased passerine abundance and territory density, with the highest increase detected in Whinchats Saxicola rubetra. No positive trend was observed in Corn Buntings Emberiza calandra. Immediately after the increase in abundance, bird distribution within the study area was not influenced by the timing of mowing. The hatching success, assessed by the systematic observation of food carrying, was negatively influenced by early mowing (<40% recorded when >60% of the meadow area was already harvested on 1 July) or, in late mown areas, by high meadow passerine territory density (<40% when territory density was >10 per 10 ha). Hatching rate was usually higher in Whinchats than in Corn Buntings. Conclusion By improving meadow passerine breeding outputs and density, mowing postponement led to instable population dynamics with dominance of certain species and density‐dependent breeding success. 相似文献
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Wei-Hsin Chen Ching-Liang Hsieh Chun-Ping Huang Tzu-Jou Lin Jason TC Tzen Tin-Yun Ho Yi-Wen Lin 《Journal of biomedical science》2011,18(1):82
Background
Peripheral tissue inflammation initiates hyperalgesia accompanied by tissue acidosis, nociceptor activation, and inflammation mediators. Recent studies have suggested a significantly increased expression of acid-sensing ion channel 3 (ASIC3) in both carrageenan- and complete Freund's adjuvant (CFA)-induced inflammation. This study tested the hypothesis that acupuncture is curative for mechanical hyperalgesia induced by peripheral inflammation. 相似文献7.
Guillaume Gayet Cyril Eraud Maurice Benmergui Joël Broyer François Mesleard Hervé Fritz Matthieu Guillemain 《European Journal of Wildlife Research》2011,57(5):1051-1056
A number of native and exotic animal species show dramatic population increases in terms of both numbers and geographic range.
Understanding the habitat selection processes behind such increases is crucial to implement adequate management measures.
Mute swan (Cygnus olor) populations have experienced a tremendous demographic and geographic expansion in Western Europe during the twentieth century,
colonizing a wide variety of aquatic habitats. We aimed at assessing how swans select nesting sites during the pre-laying
and laying periods on medium to large fishponds (from 10 to 50 ha) in Eastern France, while accounting for detectability biases
and testing for the effects of fishpond spatial configuration, vegetation resources, human disturbance and habitat management.
Our results demonstrate that the mute swan is a non-selective species regarding its nesting habitat among such fishponds,
using these independently from the parameters considered although fishpond characteristics varied. Although mute swan is one
of the least cryptic Anatidae, owing to its white colour and large size, detection of breeding pairs remained imperfect for
each over several sampling occasions. However, because we repeated the sampling sessions, detection of swan pairs by the end
of the monitoring period was as high as 0.94. These results are consistent with previous assertions that the mute swan is
a species of high ecological plasticity, which may partly explain its recent colonization rates. Given that even swan breeding
events were imperfectly detected on each occasion, we highlight the fact that most studies of breeding ducks (which are more
cryptic) would be considerably improved by better considering detection biases. 相似文献
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Background
Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing novel information on functional properties of proteins and their roles in the grand scheme of evolutionary biology. Currently, the structural similarity between two proteins is measured by the root-mean-square-deviation (RMSD) in their best-superimposed atomic coordinates. RMSD is the golden rule of measuring structural similarity when the structures are nearly identical; it, however, fails to detect the higher order topological similarities in proteins evolved into different shapes. We propose new algorithms for extracting geometrical invariants of proteins that can be effectively used to identify homologous protein structures or topologies in order to quantify both close and remote structural similarities. 相似文献9.
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