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排序方式: 共有51条查询结果,搜索用时 15 毫秒
1.
S M Borodkin O M Grindel' G N Boldyreva V A Za?tsev V I Luk'ianov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1987,37(1):22-30
EEGs of 15 healthy subjects and 30 patients in early period after surgical ablation of tumours with basal localization, were investigated by means of monitor "Neuro-1" which allows to obtain in continuous regime characteristics of EEG dynamics according to power spectra and reveal the characteristics of intercentral relations of electrical brain processes by coherence and phase shifts. In healthy subjects in the period of transition from wakefulness to drowsiness highly coherent beta-rhythm (16-18 Hz) was revealed, preceeding typical picture of drowsiness and sleep. Study of the patients shows that certain characteristics of coherence and phasic shifts have an important prognostic value. Conclusion is made that for estimation of the functional state of healthy subjects during transition from wakefulness to drowsiness and of patients in early postoperative period the data on spectra of coherence are most informative. 相似文献
2.
I K Iaichnikov Iu S Borodkin 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1988,38(2):342-349
In chronic experiments on rabbits, in initial period of single action of ethanol, reduction was observed of the dominating frequency of the theta-rhythm and synchroneity of summated bioelectrical activity of homotopic zones and suppression of EEG manifestation but preservation of parameters of the interhemispheric zeta-wave and of temperature asymmetry in the dorsal hippocampus in response to electro-cutaneous stimulation. Late period of ethanol action was characterized by lowering of the amplitude of superslow activity, its inversion in symmetrical areas of the visual neocortex and instability of other parameters. 相似文献
3.
The effect of neurotensin on submaximally-stimulated hepatobiliary and pancreatic secretion was studied in 6 healthy subjects. An intravenous infusion of neurotensin 1.4 ± 0.3 pmol/kg/min, designed to reproduce plasma neurotensin immunoreactivity levels within the physiological range, produced a significant increase in pancreatic bicarbonate output. Plasma concentrations of pancreatic polypeptide rose by 83 ± 16 pmol/l and were associated with a small reduction in trypsin, but no significant change in bilirubin outputs. 相似文献
4.
L T Kushashvili A K Zhuravlev A G Borodkin G V Popova A D Nekliudov 《Antibiotiki i khimioterapii͡a》1988,33(1):16-22
The process of asymmetric deacylation of an acetyl derivative of 5-benzyl hydroxytryptophan racemate in the presence of native microbial aminoacylase was studied. The effect of pH, temperature, concentration of the enzyme and substrate were investigated. Conditions for preparation and isolation of individual amino acids were defined by optimization of N-Ac-DU-5-BOT hydrolysis. 相似文献
5.
A theory of a coaxial back-wave ubitron pumped by a high-current relativistic electron beam is constructed. The start currents of an ubitron are determined. The nonlinear dynamics of microwave generation at different electron beam currents is investigated. 相似文献
6.
A patient who developed an irregular sleep-wake pattern following prolactin-secreting pituitary microadenoma is described. The patient reported difficulties in sleep onset and awakening at the desired time, which caused major dysfunction in his daily life activities. Despite these difficulties, the sleep-related complaints of the patient remained unrecognized for as long as three yrs. Statistical analyses of the patient's rest-activity patterns revealed that the disruption of the sleep-wake circadian rhythm originated from a disharmony between ultradian (semicircadian) and circadian components. The circadian component displayed shorter than 24 h periodicity most of the time, but the semicircadian component fluctuated between longer and shorter than 12 h periods. Additionally, desynchrony in terms of period length was found in the tentative analyses of the rest-activity pattern, salivary melatonin, and oral temperature. While the salivary melatonin time series data could be characterized by a best-fit cosine curve of 24 h, the time series data of oral temperature was more compatible with 28 h best-fit curve. The rest-activity cycle during the simultaneous measurements, however, was best approximated by a best-fit curve of 21 h. The dysregulation of circadian rhythms occurred concomitantly, but not beforehand, with the onset of pituitary disease, thus suggesting an association between the two phenomena. This association may have interesting implications to the modeling of the circadian time-keeping system. This case also highlights the need to raise the awareness to circadian rhythm sleep disorders and to consider disruptions of sleep-wake cycle in patients with pituitary adenoma. 相似文献
7.
Obituary
In memory of Yakov Borisovich Fainberg (September 7, 1918–March 7, 2005) 相似文献8.
M S Usatenko S O Burmistrov N E Sokolovskaia Iu V Nikolaev Iu S Borodkin 《Biulleten' eksperimental'no? biologii i meditsiny》1984,97(4):426-429
Cross immunoelectrophoresis was used to study antigenic composition of the brain of rats preferring water, or 15% ethanol and of intermediate group animals. The rat brain showed 6 antigens, one of them was found to be neurospecific. The intermediate group animals and those preferring ethanol differed from those preferring water in that they demonstrated two antigens which were found to be neuro-nonspecific. The content of the neurospecific protein S-100 in the cerebellum measured by rocket immunoelectrophoresis was demonstrated to be the same in animals preferring water and ethanol. A single intraperitoneal injection of 25% ethanol (2.5 g/kg) to the intermediate group rats brought about a change in the composition of neuro-nonspecific soluble antigens of the brain. 相似文献
9.
A Puri R Sethi B Singh SK Dwivedi VS Narain RK Saran VK Puri 《Indian pacing and electrophysiology journal》2009,9(3):186-189
A 25-year-old previously asymptomatic pregnant woman at 36 weeks'' gestation was noticed to have repetitive monomorphic ventricular tachycardia. A dilated left ventricle with moderately reduced systolic function was found on echocardiographic examination. This is a very rare presentation of peripartum cardiomyopathy (PPCMP) presenting with repetitive monomorphic ventricular tachycardia. 相似文献
10.
A recently silenced, duplicate PgiC locus in Clarkia 总被引:1,自引:0,他引:1
Previous electrophoretic analysis showed that 17 diploid species of the
wildflower Clarkia (Onagraceae) have two cytosolic isozymes of
phosphoglucose isomerase (PGIC; EC 5.3.1.9), whereas 15 other diploid
species have a single PGIC. Molecular studies revealed that the two
isozymes in the former species are encoded by duplicate genes, PgiC1 and
PgiC2, whereas the single isozyme in the latter is always encoded by PgiC1.
Phylogenetic analysis of the nucleotide sequences implied that PgiC2 was
silenced four times independently in the genus. Here we describe a psi
PgiC2 from C. mildrediae, a species in which only PgiC1 is expressed. The
discovery of the psi PgiC2 is significant because it confirms a formal
prediction of the phylogenetic analysis. The psi PgiC2 includes 5,039
nucleotides corresponding to 18 of the 23 exons of PgiC, as well as the
intervening introns and 3' nontranslated region. The absence of an increase
of nucleotide substitutions in its "exons" suggests that the gene was
silenced recently. The present study appears to be the first to establish
that a specific duplicate gene locus regularly expressed in a group of
related plant species has been silenced in one of them. The multiple
independent silencings of PgiC2 suggest that it remained functional but
inessential in ancestral lineages. We discuss the possibility that PgiC2
may have been preserved in these lineages by selection against mutants
causing defective PGIC1- PGIC2 heterodimers.
相似文献