The kinetics of the inactivation of the soybean trypsin inhibitor by heat processing]

The investigations of kinetics of the thermal degradation of the antinutritious substances in the soya beans were carried out. The mathematical analysis of the obtained experimental data helped to determine the kinetic constants D and Z necessary to calculate the time of heat treatment to obtain the minimal value of the inhibitor at any temperature level.     

Reaction of rat embryo tissues to mechanical trauma and to infection with Staphylococcus aureus (strain 209)]

Experiments were conducted on albino rat embryos. A study was made of healing of the skin wounds and the reaction of the tissues to the intrauterine injection of pathogenic Staphylococcus aureus (strain 209). In horizontal cut the orthotonic position of the fetus and retraction of the skeletal muscles prevented wound contraction and epithelialization of its surface. In vertical cut the margins of the wound were approximated and healing took place without formation of granulation tissue by epithelialization of the wound surface 2 days after the operations with regeneration of the squamous epithelium. To the action of the pathogenic staphylococcus the embryos responded by a local untypical reaction with the prevalence of alterative changes and the accumulation of the histiocyte-like cells near some colonies. There was no exudative inflammatory reaction either during the trauma or in injection of a staphylococcus culture at all the periods of the intrauterine life.     

Mechanisms of excising the P-element in a model system at the yellow locus of Drosophila melanogaster]

Patterns of excision of a single P element were studied in a model system of the yellow locus. The data obtained were in good agreement with the generally accepted SDSA (synthesis-dependent strand annealing) model. Specific features of P element excision in the presence of two tandemly repeated copies are presented. The pattern of P element excision depended on the sequences surrounding the insertion site and on the number of its additional copies present in the genome.     

Function and reactivity of the microvascular bed in human neuroses

By contact microscopy the state and reactivity of the capillary bed (capillaries of the cheek mucosa) were studied in neurotic patients with different levels of arterial pressure (AP). It has been shown that at constant AP capillariscopic parameters (diameter, length and number of capillaries in the visual field) are relatively stable. Neuroses with hypertension are characterized by uneven (more expressed in arterioles) contraction of the capillaries, accelerated development and greater duration of reactions to the mental stress and applications of adrenaline and noradrenaline solutions in comparison with healthy persons. In hypotension, uniform capillaries contraction and slower development of the above reactions are observed.