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A convenient technology to quantify three-dimensional (3D) morphological features would have widespread applications in biomedical research. Based on combined improvements in sample preparation, tomographic imaging and computational processing, we present a procedure for high-resolution 3D quantification of structures within intact adult mouse organs. Using the nonobese diabetic (NOD) mouse model, we demonstrate a correlation between total islet beta-cell volume and the onset of type-1 diabetes.  相似文献   
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Asayesh  G.  Mohebbi  G. H.  Nabipour  I.  Rezaei  A.  Vazirizadeh  A. 《Biology Bulletin》2021,48(3):263-273
Biology Bulletin - Different extracts of solitary marine tunicates have attracted attention as a source of amazing secondary metabolites with a wide range of promising potential biological effects....  相似文献   
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Biological Trace Element Research - The prevalence of cardiometabolic risk factors has been increasing worldwide. The results of reported studies on the effects of zinc supplementation on...  相似文献   
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