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排序方式: 共有120条查询结果,搜索用时 15 毫秒
1.
T. A. Gudasheva K. N. Koliasnikova T. A. Antipova S. B. Seredenin 《Doklady. Biochemistry and biophysics》2016,469(1):273-276
It was shown for the first time that the endogenous cyclic dipeptide cycloprolylglycine (CPG) at concentrations of 10–7 and 10–3 M and piracetam at a concentration of 10–3 M increased the content of brainderived neurotrophic factor (BDNF) in the culture of neuronal cells in normal state and under conditions of glutamate and 6-oxydopamine neurotoxicity. This may indicate the possible involvement of BDNF in the mechanism of action of neuropeptide CPG and piracetam. 相似文献
2.
EA Dukhanina TI Lukyanova EA Romanova V Guerriero NV Gnuchev GP Georgiev DV Yashin LP Sashchenko 《Cell cycle (Georgetown, Tex.)》2015,14(22):3635-3643
PGRP-S (Tag7) is an innate immunity protein involved in the antimicrobial defense systems, both in insects and in mammals. We have previously shown that Tag7 specifically interacts with several proteins, including Hsp70 and the calcium binding protein S100A4 (Mts1), providing a number of novel cellular functions. Here we show that Tag7–Mts1 complex causes chemotactic migration of lymphocytes, with NK cells being a preferred target. Cells of either innate immunity (neutrophils and monocytes) or acquired immunity (CD4+ and CD8+ lymphocytes) can produce this complex, which confirms the close connection between components of the 2 branches of immune response. 相似文献
3.
V. P. Zhelifonova T. V. Antipova S. M. Ozerskaya G. A. Kochkina A. G. Kozlovsky 《Microbiology》2009,78(3):350-354
Species identification of slow-growing fungi of the genus Penicillium isolated from ancient permafrost deposits was performed using micro- and macromorphological characteristics as well as the composition of secondary metabolites. The strains producing clavine ergot alkaloids fumigaclavines A and B and festuclavine were assigned to the species P. palitans Westling 1911, whereas the strains forming ochratoxins A and B were identified as P. verrucosum Dierckx 1901. 相似文献
4.
Rystsov G. K. Antipova T. V. Zaitsev K. V. Zemskova M. Yu. 《Russian Journal of Bioorganic Chemistry》2021,47(1):307-316
Russian Journal of Bioorganic Chemistry - It has been found that monasnicotinic acid (MNA) isolated from the fungus Aspergillus cavernicola VKM F-906 reduces the proliferation and migration of... 相似文献
5.
A. G. Kozlovskii V. P. Zhelifonova T. V. Antipova 《Applied Biochemistry and Microbiology》2013,49(1):1-10
Fungi of the genus Penicillium isolated from little studied habitats are able to synthesize both previously known and new physiologically active compounds with diverse structures. They include secondary metabolites of alkaloid nature, i.e., ergot alkaloids, diketopiperazines, quinolines, quinazolines, benzodiazepines, and polyketides. We discuss the use of profiles of secondary metabolites for taxonomy purposes. Studying the physicochemical characteristics of producers of biologically active compounds showed that the biosynthesis of alkaloids is initiated on the first days of cultivation and proceeds simultaneously with growth. The cyclic character of alkaloid accumulation was recorded related to the processes of alkaloid biosynthesis, excretion from cells, degradation in culture fluid, and consumption by cells. Synchronic variations in the concentrations of intracellular tryptophan and alkaloids are necessary for the regulation of the optimal quantity of tryptophan necessary for the culture. 相似文献
6.
Sazhina N. N. Antipova A. S. Semenova M. G. Palmina N. P. 《Russian Journal of Bioorganic Chemistry》2019,45(1):34-41
Russian Journal of Bioorganic Chemistry - Design and research of liposome structures on the basis of soy phosphatidylcholine (PC) as nanocontainers for delivery of various functional nutraceuticals... 相似文献
7.
Slizhikova DK Zinov'eva MV Kuz'min DV Snezhkov EB Shakhparonov MI Dmitriev RI Antipova NV Zavalova LL Sverdlov ED 《Molekuliarnaia biologiia》2007,41(4):659-665
Secretory polymeric immunoglobulins (IgA dimers and IgM pentamers) are unique in that, apart from L- and H-chains, they contain J-chains responsible for their oligomerization. These antibodies are part of the local adaptive immune system acting on mucosa membranes of the respiratory and digestive systems as the first protection barrier to potential infectious agents. Secretory polymeric immunoglobulins are produced by highly specific B-cells and actively transported to the surface of mucosa membrane through epithelium cells. Therefore, their synthesis and J-chain content are dependent upon epithelium translocation function and condition that are markedly affected by tumorous transformation. Here, we used RT-PCR and immunoblotting to study of the J-chain content and its mRNA expression level in normal and tumorous tissues in lung squamous cell cancer and adenocarcinoma at various stages of disease progression. 相似文献
8.
Kirichuk VF Ivanov AN Antipova ON Krenitskiĭ AP Maĭborodin AV Tupikin VD Betskiĭ OV 《Tsitologiia》2007,49(6):484-490
The influence of electromagnetic waves of terahertz range at the frequencies of molecular spectrum o nitric oxide radiation and absorption on functional activity of thrombocytes in white rats under long-term stress has been studied. It has been shown that courses of THzF treatment applied during the stress can prevent and restore disorders in thrombocytes aggregative function. The stress factor does not induce characteristic of stress-reaction disturbances of microcirculation in animals treated with the preventive course of THzF. 相似文献
9.
10.
Kozlovskiĭ AG Zhelifonova VP Antipova TV 《Prikladnaia biokhimiia i mikrobiologiia》2005,41(5):568-572
Quinocitrinines and ergot alkaloids are synthesized by the strain Penicillium citrinum VKM FW-800 as the culture grows. The major part of these secondary metabolites are secreted into the medium. In the phase of growth deceleration, these metabolites were partly absorbed by the producer cells. Zinc ions stimulated both the primary and secondary metabolic processes. Addition of this microelement into the culture medium stimulated biomass accumulation and the synthesis of clavine alkaloids and quinocitrinines. 相似文献