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排序方式: 共有319条查询结果,搜索用时 15 毫秒
1.
2.
S Glazer M M Vartanova N N Konstantinova 《Biulleten' eksperimental'no? biologii i meditsiny》1985,100(10):414-415
Significant adverse correlation of the fetus mass and the degree of its hydration was noted at term in rats with placental insufficiency induced by ligation of about 40% of preplacental vessels on the 16th day of gestation. Disorders revealed in transplacental water-salt metabolism are apparently of some importance for the pathogenesis of fetal growth retardation. Even moderate retardation alters fetal respiratory activity in anoxia, which is associated with the changes in the function of respiratory centres and neuromuscular abnormalities. 相似文献
3.
T N Kuchma N D Konstantinova I S Samo?lenko 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1990,(9):20-23
The comparative study of the action of microwave radiation and hydrogen peroxide, as well as their combined action, on the viability and ultrastructure of P. aeruginosa cells has been made. The combined use of microwave radiation and hydrogen peroxide has been shown to decrease the viability of P. aeruginosa 1.5-2 times in comparison with the isolated action of each factor. The electron microscopic study of the ultrastructure of cells have shown the deterioration of the surface structures, nuclear and ribosomal apparatus of the cells under the isolated action of each of the above-mentioned factors or under their combined action. The morphological picture of these changes has proved to be different. The maximum changes in the ultrastructure of P. aeruginosa cells have been registered after the combined action of these bactericidal factors. 相似文献
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5.
M S Konstantinova T P Semenova N I Grishchenko E A Gromova A L Polenov 《Ontogenez》1989,20(3):332-336
A neurotoxin 6-hydroxydopamine (6-OHDA) was introduced to 1, 2 and 3 day old male Wistar rats. Falck-Hillarp histochemical fluorescent method was used to analyze hypothalamic and hypophysial structures containing catecholamines. Statistically reliable decrease in catecholamine fluorescence intensity in hypothalamus and hypophysis, accumulation of catecholamines in nerve cells of supraoptic nucleus and in tanycytes of median eminence differed in 25- and 90-days rats. Disturbance of catecholaminergic systems of hypothalamus and hypophysis induced by neonatal introduction of 6-OHDA leads to reliable relaxation of orienting reaction and deep violation of learning that becomes stronger with age. 相似文献
6.
Lydiya I. Sergeeva Ivana Macháčková Tatyana N. Konstantinova Svetlana A. Golyanovskaya Josef Eder Oksana O. Zaltsman Jan Hanuš Nina P. Aksenova 《Journal of Plant Growth Regulation》1994,13(3):147-152
The levels of endogenous IAA and cytokinins (zeatin, zeatin riboside, isopentenyladenine, and isopentenyladenosine) were determined in potato plants cultured in vitro under red light (R) and blue light (B) on medium with or without hormones. On medium without hormones in B, plants contained much higher cytokinin levels, particularly in leaves and roots, and also slightly elevated IAA levels. Kinetin in the medium in B changed the distribution of cytokinins and significantly increased IAA level in roots. In R, the presence of kinetin led to an increased cytokinin level in the whole plant, while the IAA level was slightly lower. IAA in the medium in B decreased cytokinin level in all plant parts, while the IAA level did not change significantly. In R, the presence of IAA in the medium led to a moderate increase of CK level and to a significant increase in IAA level, especially in roots. Uptake of 1-14C-IAA and of 3H-zeatin was generally higher in B than in R. Higher percentage of IAA taken up in B was converted to conjugates in the roots. Metabolism of 3H-zeatin was similar in R and B with only slight differences in metabolite amounts.Thus, in all experimental situations in which tuber formation was stimulated, IAA level in roots and stolons rose significantly, stressing the importance of an IAA gradient for tuber formation. 相似文献
7.
L N Kats N A Zigangirova N D Konstantinova S V Prozorovski? 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1984,(9):50-54
The unbalanced growth forms (UGF), also known as heteromorphous or pleomorphous forms, of salmonellae were obtained under the action of penicillin, homologous antiserum in combination with complement and lysozyme, as well as ultraviolet radiation. The effect of these factors was studied after their momentaneous action and in successive passages. The viability of UGF was determined in terms of colony-forming units. The appearance of UGF was induced by penicillin, a complex of immune substances and ultraviolet radiation, yet the action of two latter factors irreparably damaged most of the cells. The formation of UGF, showing stability in prolonged passages and capable of transformation into L-forms, occurred only under the influence of penicillin. Elementary bodies appeared in UGF, both capable and incapable of transformation into L-forms after successive passages. In the viable part of the UGF population obtained under the action of all the above factors damages in the peptidoglycan layer of the cell wall and, partly, in the cytoplasmic membrane, as well as disturbances in the process of cell division, linked with these cell elements, were observed. 相似文献
8.
Computerized analysis of sparse matrix, based on the list of involved organs, body parts, extremities, function etc. (total item number about 600) was performed for different cytogenetically identified anomalies of human chromosome 4 (35 cases of 4p-, 32 cases of 4p+, 39 cases of 4q-, 39 cases of 4q+; both published and original data were used). For each of the four types of partial aneusomy, 4 specific enough groups of traits were revealed which had been found in 50% of respective patients, at least. Such "nuclei" of traits were highly similar to those given in comprehensive modern manuals. However, 4p- and 4q- could only be classified as strictly enough delineated chromosomal syndromes. The 4(p14-pter) region was found to be the most likely crucial segment for the Wolf-Hirschhorn syndrome. 相似文献
9.
Prof. Dr. A. L. Polenov Dr. M. A. Belenky M.Sc. P. E. Garlov M. S. Konstantinova 《Cell and tissue research》1976,170(1):113-128
Summary The proximal neurosecretory contact region (PCR) of Acipenseridae, a homologue of the tetrapod median eminence, has been studied by light, fluorescence and electron microscopy. It occupies the rostral and chiefly the ventral surfaces of the hypothalamic tuber cinereum. PAF-positive fibres occur in the zone of the preoptico-hypophysial tract but their terminal enlargements are concentrated mainly in the external zone. They make contact with the primary portal capillaries situated in the pia mater. Monoaminergic fibres and terminals with an intense green fluorescence are localized in the same regions. The fibres of some bipolar monoaminergic neurons of the PCR make contact both with the third ventricle and the primary portal capillaries.Three types of granule-containing neurosecretory fibres and terminals have been recognized in the PCR. Fibres of types A1 (d=120–300 nm) and A2 (d=100–170 nm) are peptidergic PAF-positive, although some fibres, including some of type A1; belong possibly to PAF-negative type. Monoaminergic type B fibres have granules 80–100 nm in diameter. Neurosecretory terminals and vascular endfeet of tanycytes make contact with the 70 nm thick outer basement membrane of the primary portal capillaries. Several laminae of thin horizontally oriented tanycyte processes form a boundary between the external zone and the preoptico-hypophysial tract. Few neuroglial cells with pale cytoplasm, numerous lysosomes and lipofuscin granules are seen in this region. It is hypothesized that, as in other vertebrates, both peptide hypophysiotropic neurohormones and monoamines are discharged from the PCR into the portal circulation and affect the activity of the glandular cells of the pars distalis.Dedicated to Prof. Dr. Drs. h.c. W. Bargmann on the occasion of his 70th birthday 相似文献
10.
Yan G. Ni Jon H. Condra Laura Orsatti Xun Shen Stefania Di Marco Shilpa Pandit Matthew J. Bottomley Lionello Ruggeri Richard T. Cummings Rose M. Cubbon Joseph C. Santoro Anka Ehrhardt Dale Lewis Timothy S. Fisher Sookhee Ha Leila Njimoluh Dana D. Wood Holly A. Hammond Douglas Wisniewski Cinzia Volpari Alessia Noto Paola Lo Surdo Brian Hubbard Andrea Carf�� Ayesha Sitlani 《The Journal of biological chemistry》2010,285(17):12882-12891