排序方式: 共有43条查询结果,搜索用时 15 毫秒
1.
2.
3.
Young D. Kwon Gwo-Yu Chuang Baoshan Zhang Robert T. Bailer Nicole A. Doria-Rose Tatyana S. Gindin Bob Lin Mark K. Louder Krisha McKee Sijy O’Dell Amarendra Pegu Stephen D. Schmidt Mangaiarkarasi Asokan Xuejun Chen Misook Choe Ivelin S. Georgiev Vivian Jin Marie Pancera Peter D. Kwong 《Cell reports》2018,22(7):1798-1809
4.
Three new species of the genus Zygnemopsis (Skuja) Trans. 1934 (Z. benghalensis sp. nov.; Z. pseudolahaulensis sp. nov., and Z. scrobiculata sp. nov.) are described from West Bengal, India. 相似文献
5.
6.
Gavai AV Vaz RJ Mikkilineni AB Roberge JY Liu Y Lawrence RM Corte JR Yang W Bednarz M Dickson JK Ma Z Seethala R Feyen JH 《Bioorganic & medicinal chemistry letters》2005,15(24):1225-5482
A 3D quantitative structure–activity relationship study for inhibition of calcium-sensing receptor in the aryloxypropanolamine series predicted that these molecules adopt a U-shaped conformation with pi-stacking between the two aromatic rings. This hypothesis led to the discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines capable of antagonizing the calcium-sensing receptor with potency comparable to that of NPS-2143. 相似文献
7.
8.
Derivatisation of diospyrin, a bisnaphthoquinonoid isolated from Diospyros montana Roxb., led to the modification of its inhibitory activity, in vitro, towards a murine tumour model, Ehrlich ascites carcinoma (EAC), and two human cancer cell lines, viz., malignant skin melanoma (A375) and epidermoid laryngeal carcinoma (Hep2). Among the novel derivatives, an epoxide exhibited the maximum antiproliferative activity (IC(50) values in the range of 0.03-0.21 microM) and a comparatively lower toxicity (IC(50) approximately 98 microM) in normal human peripheral blood mononuclear cells (PBMC). This compound might provide a novel 'lead' for the development of clinically effective antiproliferative agents against cancer. 相似文献
9.