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A complex pattern of regulation of the cartilage matrix protein gene was revealed by transient expression experiments. A minimal promoter from positions -15 to +64 functioned in chondrocytes and fibroblasts. An enhancer located in the first intron exerted chondrocyte-specific stimulation on the minimal promoter activity. The same fragment, however, had a negative effect in fibroblasts. Between -334 and -15, a silencer was found which inhibited the gene expression driven from its homologous as well as heterologous promoters both in chondrocytes and fibroblasts. Additional positive and negative control regions were mapped further upstream of the promoter.  相似文献   
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[目的]多年来,蒙古高原典型落叶松害虫雅氏落叶松尺蠖Eeannis jacobssoni发生频繁,使森林生态系统遭到严重破坏.虫口密度可直接描述森林虫害严重程度,进而及时、快速获得害虫虫口密度信息显得极为重要.本研究旨在依据雅氏落叶松尺蠖暴发区的落叶松光谱实测数据和虫口密度数据,构建基于高光谱特征的虫口密度估算方法.[...  相似文献   
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