全文获取类型
收费全文 | 1095篇 |
免费 | 73篇 |
国内免费 | 1篇 |
专业分类
1169篇 |
出版年
2023年 | 5篇 |
2022年 | 19篇 |
2021年 | 28篇 |
2020年 | 18篇 |
2019年 | 15篇 |
2018年 | 26篇 |
2017年 | 25篇 |
2016年 | 22篇 |
2015年 | 39篇 |
2014年 | 60篇 |
2013年 | 108篇 |
2012年 | 72篇 |
2011年 | 87篇 |
2010年 | 48篇 |
2009年 | 52篇 |
2008年 | 77篇 |
2007年 | 60篇 |
2006年 | 57篇 |
2005年 | 54篇 |
2004年 | 51篇 |
2003年 | 48篇 |
2002年 | 50篇 |
2001年 | 6篇 |
2000年 | 17篇 |
1999年 | 19篇 |
1998年 | 8篇 |
1997年 | 3篇 |
1996年 | 4篇 |
1995年 | 4篇 |
1994年 | 3篇 |
1993年 | 8篇 |
1992年 | 8篇 |
1991年 | 8篇 |
1990年 | 6篇 |
1989年 | 7篇 |
1988年 | 6篇 |
1987年 | 8篇 |
1986年 | 2篇 |
1985年 | 5篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1971年 | 1篇 |
1969年 | 2篇 |
1966年 | 2篇 |
1962年 | 2篇 |
排序方式: 共有1169条查询结果,搜索用时 0 毫秒
1.
2.
S. K. Podder A. Chakraborti K. Vijayalakshmi P. Lalit Kumar Singh 《Journal of biosciences》1987,11(1-4):495-502
To examine how surface Potential controls the reactivity of glycoconjugates at cell surface, the interaction of galactose-sPecific
lectinse.g. peanut agglutinin,Ricinus cummunis agglutinin with liPosomes bearing asialo GM1 were studied in the Presence of varying amount of ganglioside mixture, GMn. The Presence of 5% GMn causes comPlete slowing down of PreciPitin reaction and thereby make carbohydrate moiety of asialo GM1 comPletely inaccessiblei.e. ‘cryPtic’. In contrast the Presence of 1–2% GMn enhances the aPParent rate and amPlitude of the PreciPitin reaction as surface Potential becomes more negative. The relevance
of the findings has been discussed in relation to the exPression and involvement of the cell-surface sialic acid residues
during develoPment and differentiation. 相似文献
3.
R. Sankar P. S. Devamanoharan G. Raghupathi M. Krishnasamy C. S. Shyamala Devi 《Journal of biosciences》1987,12(3):267-271
Plumbagin was administered to rats at a concentration of 1,2,4,8 and 16 mg per kg body weight. After 24 h lipid peroxide levels
were found to decrease in subcellular fractions of liver. Plumbagin inhibited ascorbate and nicotinafde adenine dinucleotide
phosphate (reduced) dependent lipid peroxidation but was without any effect on cumene hydroperoxide dependent lipid peroxidation.
Injection of 16 mg of plumbagin per kg body weight was found to decrease liver total reduced glutathione and also fcrosomal
glucose-6-phosphatase. The results are discussed with reference to the anti- and prooxidant properties of plumbagin. 相似文献
4.
The large family of signal transducing proteins known as G proteins are heterotrimers that dissociate into an independent α-subunit and βγ-subunit complex after ligand binding or other stimulation. For Gα, at least 30 distinct sequences representing 10 different classes have been identified. On the other hand, cDNAs for only three Gβ-subunit genes have been isolated so far. All three of the Gβ genes have been chromosomally mapped in the human, but only two in the mouse. Using a human retinal cDNA for the third G protein β-subunit, we have mapped the corresponding gene, termed Gnb-3, to mouse Chromosome 6 with somatic cell hybrids and have positioned it distal to but near the marker Raf-1 by analysis of the progeny of three genetic crosses. 相似文献
5.
6.
Antisera towards neurotensin (NT) and the structurally related peptide, LANT6, were used to characterize immunoreactive peptides and proteins in extracts of chicken tissues. A 17 kDa protein was identified by Western blotting as a potential precursor to NT and LANT6. However, the posttranslational processing of this common precursor appeared to be tissue specific, giving rise to disproportionate amounts of NT and LANT6, along with varying expression of a large molecular LANT6 (Mr, 15 kDa). The intestinal cells containing immunoreactive NT, LANT6, and large molecular LANT6 behaved similarly during fractionation by size and density. These activities also banded together in particles resembling vesicles during centrifugation of isotonic homogenates of tissue. These results suggest that chicken NT and LANT6 are biosynthesized as parts of the same precursor, the processing of which can give rise to a variety of products stored within secretory vesicles. 相似文献
7.
The antimicrobial activities of six withanolide compounds are compared. 相似文献
8.
Harshad S. Ugamraj Kevin Dang Laure-Hlne Ouisse Benjamin Buelow Eduardo N. Chini Giulia Castello James Allison Starlynn C Clarke Laura M. Davison Roland Buelow Rong Deng Suhasini Iyer Ute Schellenberger Sankar N. Manika Shipra Bijpuria Astrid Musnier Anne Poupon Maria Cristina Cuturi Wim van Schooten Pranjali Dalvi 《MABS-AUSTIN》2022,14(1)
9.
How cells regulate the size of intracellular structures and organelles is a longstanding question. Recent experiments suggest that size control of intracellular structures is achieved through the depletion of a limiting subunit pool in the cytoplasm. While the limiting pool model ensures organelle-to-cell size scaling, it does not provide a mechanism for robust size control of multiple co-existing structures. Here we develop a generalized theory for size-dependent growth of intracellular structures to demonstrate that robust size control of multiple intracellular structures, competing for a limiting subunit pool, is achieved via a negative feedback between the growth rate and the size of the individual structure. This design principle captures size maintenance of a wide variety of subcellular structures, from cytoskeletal filaments to three-dimensional organelles. We identify the feedback motifs for structure size regulation based on known molecular processes, and compare our theory to existing models of size regulation in biological assemblies. Furthermore, we show that positive feedback between structure size and growth rate can lead to bistable size distribution and spontaneous size selection. 相似文献
10.
Kuvalekar Aniket Pawar Pankaj Khare Ankita Gandhe Kanchanganga Harsulkar Abhay 《Plant Cell, Tissue and Organ Culture》2008,94(1):101-104
Ravenelia esculenta Naras. and Thirum. is a rust, pathogenic to Acacia eburnea Willd. The infection leads to hypertrophy changing the morphology with bizarre shapes of plant organs. Healthy and infected
tissues were subjected to extraction of IAA and indole derivatives and were estimated by spectrophotometric methods. The hypertrophy
produced was presumed to be due to increase in the indole-3-acetic acid (IAA) content in the infected tissue, however, the
amount of IAA in infected tissues decreased with the progression of disease. Concomitantly, the infected tissue showed the
presence of a novel, slow migrating, indole derivative on TLC. Cultured shoot tips of Withania somnifera were dosed with the methanolic extract of the infected hypertrophied tissue (MEHT) (0.25, 0.5, 0.75, 1.00 and 1.25 mg/l).
The stimulation in shoot growth along with profuse rooting was observed in a dose dependent manner with maximum at 1.00 and
1.25 mg/l concentration. 相似文献