全文获取类型
收费全文 | 6726篇 |
免费 | 438篇 |
国内免费 | 8篇 |
专业分类
7172篇 |
出版年
2023年 | 55篇 |
2022年 | 163篇 |
2021年 | 298篇 |
2020年 | 131篇 |
2019年 | 165篇 |
2018年 | 221篇 |
2017年 | 164篇 |
2016年 | 196篇 |
2015年 | 321篇 |
2014年 | 351篇 |
2013年 | 503篇 |
2012年 | 509篇 |
2011年 | 445篇 |
2010年 | 258篇 |
2009年 | 224篇 |
2008年 | 259篇 |
2007年 | 273篇 |
2006年 | 238篇 |
2005年 | 210篇 |
2004年 | 214篇 |
2003年 | 175篇 |
2002年 | 175篇 |
2001年 | 126篇 |
2000年 | 109篇 |
1999年 | 84篇 |
1998年 | 44篇 |
1997年 | 41篇 |
1996年 | 40篇 |
1995年 | 28篇 |
1994年 | 26篇 |
1992年 | 64篇 |
1991年 | 74篇 |
1990年 | 76篇 |
1989年 | 62篇 |
1988年 | 69篇 |
1987年 | 49篇 |
1986年 | 41篇 |
1985年 | 55篇 |
1984年 | 50篇 |
1983年 | 45篇 |
1982年 | 26篇 |
1980年 | 32篇 |
1979年 | 39篇 |
1978年 | 43篇 |
1977年 | 34篇 |
1976年 | 35篇 |
1974年 | 40篇 |
1973年 | 27篇 |
1971年 | 25篇 |
1970年 | 27篇 |
排序方式: 共有7172条查询结果,搜索用时 0 毫秒
1.
Magnetic field influence on unsteady free convection flow of a second grade fluid near an infinite vertical flat plate with ramped wall temperature embedded in a porous medium is studied. It has been observed that magnitude of velocity as well as skin friction in case of ramped temperature is quite less than the isothermal temperature. Some special cases namely: (i) second grade fluid in the absence of magnetic field and porous medium and (ii) Newtonian fluid in the presence of magnetic field and porous medium, performing the same motion are obtained. Finally, the influence of various parameters is graphically shown. 相似文献
2.
3.
Perspective texture synthesis has great significance in many fields like video editing, scene capturing etc., due to its ability to read and control global feature information. In this paper, we present a novel example-based, specifically energy optimization-based algorithm, to synthesize perspective textures. Energy optimization technique is a pixel-based approach, so it’s time-consuming. We improve it from two aspects with the purpose of achieving faster synthesis and high quality. Firstly, we change this pixel-based technique by replacing the pixel computation with a little patch. Secondly, we present a novel technique to accelerate searching nearest neighborhoods in energy optimization. Using k- means clustering technique to build a search tree to accelerate the search. Hence, we make use of principal component analysis (PCA) technique to reduce dimensions of input vectors. The high quality results prove that our approach is feasible. Besides, our proposed algorithm needs shorter time relative to other similar methods. 相似文献
4.
M N Lorenzo R Y Khan Y Wang S C Tai G C Chan A H Cheung P A Marsden 《Biochimica et biophysica acta》2001,1522(1):46-52
Generation of the functionally pleiotropic members of the endothelin vasoactive peptide family is critically catalyzed by unique type II metalloproteases, termed endothelin converting enzymes (ECE). Isolation of human ECE-2 (EC 3.4.24.71) cDNAs revealed deduced open reading frames of 787 and 765 amino acids with approximately 60% identity with human ECE-1. Characterization of mRNA variants revealed mRNA structural diversity at the 5'-terminus. Two mRNA species exist containing distinct first and second exons. Furthermore, in one of these species, an in-frame deletion of the intracytoplasmic domain removed 29 amino acids. Because of the previously reported human genetic diseases ascribed to germline mutations of member genes of the endothelin family, ECE2 was localized in human chromosomes with fluorescence in situ hybridization and radiation hybrid mapping to 3q28-q29 and SHGC-20171/D3S1571, respectively. 相似文献
5.
A rapid, sensitive, assay for enzymes that degrade heparin is described. The procedure is based on the interference of heparin with color development during the interaction of protein with the dye Coomassie brilliant blue. The loss of this property when the glycosaminoglycan is degraded by heparinase can be used to quantify activity of the enzyme in pure form, or in complex biological samples such as tissue homogenates or serum. The assay is also suitable for studying dependence of heparinase activity under conditions such as varying pH and temperature. 相似文献
6.
Wetlands Ecology and Management - 相似文献
7.
Lela Jovanovich Sally Levin M. A. Q. Khan 《Journal of biochemical and molecular toxicology》1987,2(3):203-213
Treatment of rats with mirex (40 ppm in diet) caused hypoglycemia, liver enlargement, and inhibition of adrenal corticosteroid-synthesizing enzyme activity. At toxic dosages (20,000 ppm mirex in diet, which has a lethal toxicity-50 [LT-50] of ten days) poisoned female rats showed severe hypoglycemia, fatty liver, adrenal hyperplasia, hypophagia, lipid mobilization, and body weight (bw) loss. A 50 μg/kg intraperitoneal (IP) dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in male rats caused similar effects two days posttreatment. Hypoglycemia could be overcome by prednisone (which also inhibited adrenocorticoid-synthesizing enzyme activities) but not by streptozotocin treatment, indicating that hypoglycemia may be related to glucocorticoid deficiency resulting from inhibition of their synthesis and not by direct effects on pancreatic β-cells. Glucocorticoid deficiency could also cause increased release of adrenocorticoid hormone (ACTH), which may enhance fat mobilization caused by hypophagia. 相似文献
8.
Waseem Hassan Mohammad Ibrahim Joao Batista Teixeira Rocha 《Chemico-biological interactions》2009,182(1):52-58
As an extension of our previous work we not only evaluated the relationship between acidosis and lipid peroxidation in rat's kidney homogenate, but also determined for the first time the potential anti-oxidant activity of diphenyl diselenide, diphenyl ditelluride and ebselen at a range of pH values (7.4–5.4). Because of the pH dependency of iron redox cycling, pH and iron need to be well controlled and for the reason we tested a number of pH values (from 7.4 to 5.4) to get a closer idea about the role of iron under various pathological conditions. Acidosis increased rate of lipid peroxidation in the absence Fe (II) in kidney homogenates especially at pH 5.4. This higher extent of lipid peroxidation can be explained by; the mobilized iron which may come from reserves where it is weakly bound. Addition of iron (Fe) chelator desferoxamine (DFO) to reaction medium completely inhibited the peroxidation processes at all studied pH values including acidic values (5.8–5.4). In the presence of Fe (II) acidosis also enhanced detrimental effect of Fe (II) especially at pH (6.4–5.4). Diphenyl diselenide significantly protected lipid peroxidation at all studied pH values, while ebselen offered only a small statistically non-significant protection. The highest anti-oxidant potency was observed for diphenyl ditelluride. These differences in potencies were explained by the mode of action of these compounds using their catalytic anti-oxidant cycles. However, changing the pH of the reaction medium did not alter the anti-oxidant activity of the tested compounds. This study provides evidence for acidosis catalyzed oxidative stress in kidney homogenate and for the first time anti-oxidant potential of diphenyl diselenide and diphenyl ditelluride not only at physiological pH but also at a range of acidic values. 相似文献
9.
10.