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991.
Long-term endurance training or physical activity has been confirmed not only to improve physical performance, but to bring about an obvious beneficial effect on human health; however, the mechanism of this effect is not clear. The most studied health adaptations in skeletal muscle response to endurance exercise are increased muscle glycogen level and insulin sensitivity, fiber type transformation toward oxi- dative myofibers, and increased mitochondrial content/function. Mitochondria are dynamic organelles in eukaryotic cells critical in physical performance and disease occurrence. The mitochondrial life cycle spans biogenesis, maintenance, and clearance. Exercise training may promote each of these processes and confer positive impacts on skeletal muscle contractile and metabolic functions. This review focused on the regula- tion of these processes by endurance exercise and discussed its potential benefits in health and disease. We presented evidence suggesting that exercise training potentiates not only the biogenesis of mitochondria but also the removal of old and unhealthy mitochondria through mitochondrial quality control. 相似文献
992.
目的观察强化控糖后加用盐酸吡格列酮治疗2型糖尿病的临床疗效。方法 60例使用口服降糖药物治疗的血糖控制不佳的2型糖尿病患者,入院后先进行胰岛素泵强化控糖治疗,患者血糖达到目标值后(FPG〈7.0 mmol/L,2 h PG〈10.0 mmol/L),改为三餐前门冬胰岛素联合睡前甘精胰岛素继续强化治疗,1周后按1:1的比例随机分为两组,一组继续使用三餐前门冬胰岛素联合睡前甘精胰岛素治疗(对照组),一组在三餐前门冬胰岛素联合睡前甘精胰岛素的基础上加用盐酸吡格列酮30 mg/日(治疗组)。1~4周我院住院治疗,5~12周门诊随访,若出现FPG及2 h PG明显下降或低血糖反应,则减少胰岛素用量。观察加用盐酸吡格列酮治疗前以及治疗12周时FPG、2 h PG、HbAlc、胰岛素用量、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、体重指数的变化情况。结果 (1)治疗组胰岛素用量明显下降,与加用盐酸吡格列酮治疗前有明显差异(P〈0.05);对照组的胰岛素用量治疗前后无明显差异(P〉0.05);(2)治疗组与对照组加用盐酸吡格列酮治疗前后FPG、2hPG均无明显差异(P〉0.05)。(3)治疗组HbAlc有所下降,与加用盐酸吡格列酮治疗前有明显差异(P〈0.05),对照组HbAlc也有所下降,差异明显(P〈0.05),但治疗后两组比较无明显差异(P〉0.05)。(4)加用盐酸吡格列酮后,治疗组TG下降,HDL-C升高,与同组治疗前相比,差异明显(P〈0.05),对照组与治疗前相比差异不明显,组间比较差异有显著性(P〈0.05)。结论在强化控糖血糖达标后,加用盐酸吡格列酮继续治疗,可以明显降低患者胰岛素的使用剂量,提高患者的依从性,并且能改善血脂代谢紊乱,对于减少心血管并发症的发生有一定益处。 相似文献
993.
【背景】豚草于20世纪80年代入侵广西省来宾市兴宾区,现已扩散至该区的部分乡(镇),2009年5月通过在广西来宾市高岭村释放广聚萤叶甲和豚草卷蛾防治豚草,3个月后释放点豚草的死亡率达98%以上。【方法】实地调查豚草卷蛾的扩散、建群情况和对当地作物的安全性。【结果】豚草卷蛾在来宾市已形成稳定种群。豚草卷蛾在对豚草的控制过程中,能在豚草生长区迅速定殖、建群,在定殖区豚草被完全控制或呈现零星分布后,该虫又会迅速向邻近成片生长的豚草区扩散、定殖。在调查中未发现豚草卷蛾对周边农作物产生为害。【结论与意义】豚草卷蛾对作物安全,可以在广西大范围释放。 相似文献
994.
995.
Several isolates of a previously unreported bacterial pathogen were discovered on common cocklebur seedlings in Chicot County, AR and Washington County, MS. Diseased plants in nature exhibited angular-shaped leaf spotting symptoms on leaf margins and central leaf areas. The isolates were cultured from diseased leaf tissue and tentatively identified as Xanthomonas spp., and their virulence on common cocklebur seedlings compared. The most virulent isolate (LVA987) was used in studies to define disease progression on cocklebur seedlings and to carry out a host range evaluation on various weeds and crop plants. High virulence was found on common cocklebur > marestail (Conyza canadensis) > giant ragweed (Ambrosia trifida) ≥ and common ragweed (Ambrosia artemisifolia). These results suggest this pathogen may be useful for the biological control of these important species of weeds. This is also highly relevant since all of these weeds have evolved resistance to one or more synthetic herbicides and are thus becoming more difficult to control with conventional herbicides. 相似文献
996.
Abstract Codling moth, Cydia pomonella, is one of the most serious pests of apple and pear worldwide. This study evaluates the efficacies of a granulovirus, a Bacillus thuringiensis (Bt) strain and their combination in the control of C. pomonella in China. A Cydia pomonella granulovirus (CpGV) was isolated from C. pomonella cadavers in an orchard in Gansu, China. Droplet-feeding bioassays showed the median lethal concentration (LC50) of this CpGV isolate (CpGV-C1) against the third instar C. pomonella larvae was 770 OBs µl?1. The LC50 values of Bt C-33 and kurstaki HD-1 against the third instar larvae were 26.3 µg ml?1 and 15.7 µg ml?1, respectively. Field tests indicated the control efficacies of CpGV-C1 and the combination of CpGV-C1 and Bt against C. pomonella larvae in apple orchards were similar to that of beta-cypermethrin. Our data demonstrated that the combination of CpGV and Bt might effectively protect apple fruits from the damage of C. pomonella larvae and had the potential to be developed as a low-cost, highly effective insecticide. 相似文献
997.
M.G. Vázquez-Martínez A. Rodríguez-Meneses A.D. Rodríguez M.H. Rodríguez 《Biocontrol Science and Technology》2013,23(9):1098-1109
Control of Anopheles albimanus, the main vector of malaria on the coast of the State of Chiapas, is based mainly on application of chemical insecticides, which has resulted in resistance to most registered insecticides. Strategies for biological control may provide sustainable alternatives. We report on the lethal effects of a native isolate of Gliocladium virens on An. albimanus larvae and adults, compared to that of strains of Beauveria bassiana and Metarhizium anisopliae. Conidial suspensions of G. virens, B. bassiana and M. anisopliae cultured on Sabouraud agar were tested in bioassays with An. albimanus larvae and adults. Mosquito larvae were more susceptible to all fungi, compared to adults. On early and late instar larvae, M. anisopliae showed the most pathogenic effect (LC50 of 1.4×105 conidia/mL in early instars; 1.1×105 conidia/mL in late instars), followed by G. virens (LC50 of 3.3×105 conidia/mL in early instars and 3.5×106 conidia/mL in late instars). Metarhizium anisopliae sensu lato and the native G. virens could be considered good choices for An. albimanus control in southern Mexico. 相似文献
998.
Abstract The larval parasitoid Asecodes hispinarum Bou?ek has been used to control the coconut hispine beetle, Brontispa longissima (Gestro) in Vietnam. Although A. hispinarum has succeeded in suppressing B. longissima in southern Vietnam, biocontrol has not succeeded in central Vietnam. One factor underlying this failure might be the high temperature during the hot season. In the present work, we examined whether A. hispinarum parasitises the beetles within the range of temperatures that occur during the hot season in central Vietnam and we evaluated the potential use of the pupal parasitoid Tetrastichus brontispae Ferrière. Development of the beetle and two parasitoids was investigated at two constant temperatures (28 and 30°C) and at fluctuating temperatures from 25 to 35°C (corresponding to temperatures during the hot season in central Vietnam). B. longissima reached adulthood in all the temperature treatments. More than 70% of A. hispinarum emerged from hosts at 28°C, but none emerged at 30°C or under fluctuating temperature conditions, indicating that A. hispinarum cannot be used as a biological control agent in central Vietnam. However, T. brontispae could reproduce the next generation at all temperatures. These results suggest that T. brontispae is a potential agent for continuous biological control of B. longissima in central Vietnam. 相似文献
999.
Shengyong Wu Xuenong Xu Yaping Zhang Jing Wang 《Biocontrol Science and Technology》2013,23(7):794-802
Abstract The onion thrips Thrips tabaci is one of the most important pests of greenhouse and open-field broccoli, onion and other crops. However, the current strategy of using synthetic pesticides for its control is inadequate and unsustainable, leading to a growing interest in novel and effective biological control alternatives such as entomopathogenic fungi. Among 20 isolates of Beauveria bassiana tested for virulence against T. tabaci in laboratory bioassays, we found strain SZ-26 as the most potent, causing 83–100% mortality in adults at 1×107 mL?1conidia after 4–7 days. Further experiments in greenhouses showed the strain SZ-26 significantly lowered the numbers of adult and larval stages. 相似文献
1000.
Light brown apple moth, Epiphyas postvittana (Walker), is a newly invasive pest in California. Habrobracon gelechiae Ashmead is an indigenous North American ectoparasitoid of lepidopterans. Using E. postvittana as the host, we determined H. gelechiae host stage preference for oviposition and suitability for larval growth: the parasitoid attacked second to fifth instars, but preferred older (third to fifth) host larvae for oviposition, laying more eggs per clutch on the largest (fifth instar). Offspring survival was better on larger (third to fifth instars) hosts. Adult survival and fecundity and immature temperature development were studied at three key temperatures. At 12°C, H. gelechiae failed to oviposit. At 22 and 30°C, H. gelechiae had, respectively, egg to adult developmental times of 15.4 and 8.7 days, adult female survival of 54.8 and 27.2 days, lifetime parasitism of 39.9 and 21.8 hosts and 181 and 151 eggs per female, an intrinsic rate of increase of 0.107 and 0.165, and mean generation time 30.7 and 18.9 days. We studied intraguild interactions with the endoparasitoid Meteorus ictericus Nees, and found that H. gelechiae did not discriminate against hosts that were parasitised by M. ictericus. Neither the paralysing venom injected by H. gelechiae or the presence of the ectoparasitoid's eggs or larvae arrested M. ictericus development. We also conducted a field release of H. gelechiae on two plant species commonly infested by E. postvittana and showed that H. gelechiae was able to locate and attack moth larvae on both hosts. 相似文献