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251.
中国九个人群耵聍的遗传多态性 总被引:6,自引:2,他引:4
报道了九个人群的耵聍位点基因。计算表明中国各族人群在耵聍位点上的遗传分化程度非常大,固定指数F_(ST)=0.22。本文根据耵聍基因频率在我国和邻近地区的分布趋势,认为亚洲东北地区应是干型基因的起源地,目前世界上耵聍位点基因频率分布格局主要是基因扩散的结果,而非选择作用造成的。 相似文献
252.
运用聚丙烯酰胺凝胶等电聚焦(PAGIF)和免疫吸引技术,研究了3个地区汉族人群的C6多态性。得到的基因频率如下:漳州市——C6*A:0.4634、C6*B:0.5000、C6*R:0.0366(C6*B2:0.0317);成都市——C6*A:0.4975,C6*B:0.4484,C6*R:0.0545(C6*B2:0.0395);哈尔滨市——C6*A:0.4708,C6*B:0.5219,C6*R:0.0073(C6*B2:0.0073)。蒙古人种的C6*A频率一般都低于0.5,高加索人种的C6*A频率一般都高于0.6。黑人则介于两者之间。蒙古人种与高加索人种的另一个区别在于前者的C6*B2频率在0.03到0.07之间,而后者几乎没有C6*B2。 相似文献
253.
Helen J. Michaels B. Benner A. P. Hartgerink T. D. Lee S. Rice Mary F. Willson Robert I. Bertin 《Evolutionary ecology》1988,2(2):157-166
Summary We examined seed-mass variation in 39 species (46 populations) of plants in eastern-central Illinois, USA. The coefficient of variation of seed mass commonly exceeded 20%. Significant variation in mean seed mass occurred among conspecific plants in most species sampled (by hierarchical ANOVA), averaging 38% of total variance. For most species, within-plant variation was the larger component of total variance, averaging 62% of total variance. Variation in seed mass among fruits within crops was significant in most species tested.We conclude that variation in seed mass among and within plants is widespread and common. There was little evidence of trade-offs between number of seeds and mean or variance of seed mass, and little correlational evidence of local competition for maternal resources. No consistent ecological (dispersal mode and growth form) correlates of variance of seed mass were evident. 相似文献
254.
E. Ann MacGregor 《Journal of Protein Chemistry》1988,7(4):399-415
Two computerized methods of predicting protein secondary structure from amino acid sequences are evaluated by using them on the -amylase ofAspergillus oryzae, for which the three-dimensional structure has been determined. The methods are then used, with amino acid alignments, to predict the structures of other -amylases. It is found that all -amylases of known amino acid sequence have the same basic structure, a barrel of eight parallel stretches of extended chain surrounded by eight helices. Strong similarities are found in those areas of the proteins believed to bind an essential calcium ion and at that part of the active site that catalyzes bond hydrolysis in the substrates. The active site, as a whole, is formed mainly of amino acids situated on loops joining extended chain to the adjacent helix. Variations in the length and amino acid sequence of these loops, from one -amylase to another, provide the differences in binding the substrates believed to account for the known variations in action pattern of -amylases of different biological origins. 相似文献
255.
Basudev Shome Albert F. Parlow Wan-Kyng Liu Hyun S. Nahm Ted Wen Darrell N. Ward 《Journal of Protein Chemistry》1988,7(4):325-339
A collaborative study from two laboratories has been undertaken to re-evaluate the human follitropin -subunit sequence (hFSH), since areas of uncertainty remain in the wake of two earlier reports. The first report was by Shome and Parlow (1974). The second, by Saxena and Rathnam (1976), proposed revisions for sequence not definitively placed in the first study, as well as some differences in other placements. We have re-examined the sequence of the hFSH with more recent methodology. This has led to revision of certain areas of the sequence and resolution of differences between the two earlier proposals. Specifically, an-Ile-Ser- is established at 21–22, Asp at 41, Arg at 44, Lys at 46, and Glu at 111. These were areas of disagreement in the earlier proposals. A definitive placement of the residues around tryptophan-27 has now been obtained by three laboratories. C-terminal heterogeneity was observed with subunits ending at residue 107, 109, or 111. N-terminal heterogeneity has been observed in all preparations examined to date. A significant population of molecules with a proteolytic nick between residues 38–39 is noted. This is very likely an artifact of the collection and processing. The preparations examined in the present studies showed no evidence of residues 112–118 proposed by Saxena and Rathnam. 相似文献
256.
Dr. Takashi Yashiro Motonaka Arai Eiko Miyashita Kayoko Yamashita Takuro Suzuki 《Cell and tissue research》1988,251(2):249-255
Summary Snell dwarf mice display remarkable retardation of growth after birth and are known to lack prolactin (PRL), thyroid stimulating hormone (TSH) and growth hormone (GH). The aim of this study was to determine the reason for these hormonal deficiencies. We examined the fine structure of the gland and its immunohistochemical staining pattern with respect to antisera raised against PRL, TSH, GH, adrenocorticotrophic hormone (ACTH) and luteinizing hormone (LH). The gland of control mice reacted immunohistochemically against all antisera used, whereas only ACTH-producing cells (ACTH cells) and LH-producing cells (LH cells) were distinguished in the dwarf mice. ACTH cells in dwarf mice varied in cell shape, although they were similar in size to those of controls. The distribution of secretory granules in the cytoplasm varied from cell to cell. LH cells in the dwarf mice showed immature features, having poorly developed rough endoplasmic reticulum and Golgi apparatus. The cells were about half the size of controls, and secretory granules were smaller. In dwarf mice, non-granulated cells were encountered in addition to granulated ACTH and LH cells. Some of them formed small clusters, characteristic cell junctions being found between the cells; they thus appeared to be follicular cells. The above results suggest that hormone deficiency in Snell dwarf mice is a result of a defect in the hormoneproducing cells in the gland. 相似文献
257.
Cannibalism as a life boat mechanism 总被引:2,自引:0,他引:2
Under certain conditions a cannibalistic population can survive when food for the adults is too scarce to support a non-cannibalistic population. Cannibalism can have this lifeboat effect if (i) the juveniles feed on a resource inaccessible to the adults; and (ii) the adults are cannibalistic and thus incorporate indirectly the inaccessible resource. Using a simple model we conclude that the mechanism works when, at low population densities, the average yield, in terms of new offspring, due to the energy provided by one cannibalized juvenile is larger than one. 相似文献
258.
Synopsis We present ways to test the assumptions of the Petersen and removal methods of population size estimation and ways to adjust
the estimates if violations of the assumptions are found. We were motivated by the facts that (1) results of using both methods
are commonly reported without any reference to the testing of assumptions, (2) violations of the assumptions are more likely
to occur than not to occur in natural populations, and (3) the estimates can be grossly in error if assumptions are violated.
We recognize that in many cases two days in the field is the most time fish biologists can spend in obtaining a population
estimate, so the use of alternative models of population estimation that require fewer assumptions is precluded. Hence, for
biologists operating with these constraints and only these biologists, we describe and recommend a two-day technique that
combines aspects of both capture-recapture and removal methods. We indicate how to test: most of the assumptions of both methods
and how to adjust the population estimates obtained if violations of the assumptions occur. We also illustrate the use of
this combined method with data from a field study. The results of this application further emphasize the importance of testing
the assumptions of whatever method is used and making appropriate adjustments to the population size estimates for any violations
identified. 相似文献
259.
Allometric methods can be used to test quantitative theories of the relationship between brain size and body size across species,
and to search for ecological, behavioural, life history, and ontogenetic correlates of brain size. Brain size scales with
an allometric exponent of around 0.75 against body size across mammals, but is closer to 0.56 for birds and for reptiles.
The slope of the allometric line often varies depending upon the taxonomic level of analysis. However, this phenomenon, at
least in mammals, may be a statistical artifact. Brain size for a given body size (relative brain size) varies among orders
in birds and mammals, and some dietary associations with relative brain size have been found in particular taxa. Developmental
status at birth is the most consistent correlate of relative brain size: precocial neonates have larger brains for a given
maternal size than altricial neonates in both birds and mammals. Altricial neonates, however, have more brain growth following
birth, and in birds also have larger relative adult brain sizes. Energetic explanations for differences in neonatal brain
growth, although attractive on theoretical grounds, have largely failed to stand up to empirical tests. 相似文献
260.
Don J. Melnick 《International journal of primatology》1988,9(3):195-231
Among rhesus macaques (Macaca mulatta)and other cercopithecine monkeys, social groups occupying adjacent home ranges (i.e., members of the same local population)
exchange individuals and genes and thus exhibit marked genetic similarities. To assess the degree to which this pattern extends
beyond the local population, the genetic structure of M. mulattaand six other primate species was determined using Nei’s (1973) gene-diversity analysis. The genetic similarities seen among
social groups in the Dunga Gali population of M. mulatta (Melnick et al.,1984a) can be seen over the entire species range. Comparison of these results with the structures of other similarly organized
primate species indicates that (1) the average social group contains most of its local population’s genetic diversity, (2)
the average local population contains the majority of the genetic diversity found in the region to which it belongs, and (3)
the proportion of species gene diversity found in the average regional population varies substantially between species. Genetic
homogeneity within local and regional populations is probably the product of gene flow. The application of a number of analytical
models of selection and gene flow strongly suggests that gene flow, genetic drift, and zoogeography offer a more parsimonious
and plausible explanation for interspecific variation in regional differentiation than does stabilizing selection. 相似文献