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991.
Lu Y Ye L Yu S Zhang S Xie Y McKee MD Li YC Kong J Eick JD Dallas SL Feng JQ 《Developmental biology》2007,303(1):191-201
Dentin matrix protein 1 (DMP1) is expressed in both pulp and odontoblast cells and deletion of the Dmp1 gene leads to defects in odontogenesis and mineralization. The goals of this study were to examine how DMP1 controls dentin mineralization and odontogenesis in vivo. Fluorochrome labeling of dentin in Dmp1-null mice showed a diffuse labeling pattern with a 3-fold reduction in dentin appositional rate compared to controls. Deletion of DMP1 was also associated with abnormalities in the dentinal tubule system and delayed formation of the third molar. Unlike the mineralization defect in Vitamin D receptor-null mice, the mineralization defect in Dmp1-null mice was not rescued by a high calcium and phosphate diet, suggesting a different effect of DMP1 on mineralization. Re-expression of Dmp1 in early and late odontoblasts under control of the Col1a1 promoter rescued the defects in mineralization as well as the defects in the dentinal tubules and third molar development. In contrast, re-expression of Dmp1 in mature odontoblasts, using the Dspp promoter, produced only a partial rescue of the mineralization defects. These data suggest that DMP1 is a key regulator of odontoblast differentiation, formation of the dentin tubular system and mineralization and its expression is required in both early and late odontoblasts for normal odontogenesis to proceed. 相似文献
992.
Gonzalez-Voyer A Székely T Drummond H 《Evolution; international journal of organic evolution》2007,61(8):1946-1955
In many parentally fed species, siblings compete for food not only by begging and scrambling, but also by violently attacking each other. This aggressive competition has mostly been studied in birds, where it is often combined with dominance subordination, aggressive intimidation, and siblicide. Previous experimental and theoretical studies proposed several life-history, morphological, and behavioral variables that may facilitate the evolution of broodmate aggression, and explain its taxonomic distribution. Here we apply phylogenetic comparative analyses for the first time to test the influence of five hypothesized facilitators of the evolution of broodmate aggression, analyzing 69 species in seven avian families using two quantitative measures of aggression: incidence and intensity. We show that incidence and intensity of aggression increase with long nestling periods and indirect feeding, and small brood size is associated with intense aggression. Large food parcels were not correlated with either the incidence or intensity of aggression. Our study suggests that indirect feeding, long nestling periods, and small broods, possibly in combination with other factors, have tended to favor the evolution of aggressive broodmate competition. 相似文献
993.
Yilmaz B Yasar E Goktepe S Alaca R Yazicioglu K Dal U Mohur H 《Obesity (Silver Spring, Md.)》2007,15(11):2683-2687
Objectives: The purpose of this study was to determine the relationship between autonomic nervous system dysfunction and basal metabolic rate (BMR), and the effect of spasticity on basal metabolic rate. Research Method and Procedures: Twenty men (11 paraplegic and 9 tetraplegic) with American Spinal Injury Association (ASIA)‐A and ‐B grade chronic spinal cord injury (SCI) participated in this study. Total body fat mass and lean tissue mass were measured in all participants using DXA by standard methods. Patients were allocated into 2 groups to determine the effect of autonomic nervous system dysfunction on BMR: Group I (T6 and upper‐level injuries with history of autonomic dysreflexia) and Group II (T7 and lower‐level injuries without history of autonomic dysreflexia). Measurements of BMR were determined by indirect calorimetry under standardized conditions. Results: There were 13 patients in Group I and 7 patients in Group II and the difference between these two in terms of time since injury, BMI, age, weight, lean tissue mass, BMR, and BMR/kg were not significant. Conclusion: We concluded that autonomic nervous system dysfunction does not affect BMR, and it might be ignored in considering energy needs in spinal cord injury. 相似文献
994.
Photosynthetic and Respiratory Acclimation to Experimental Warming for Four Species in a Tallgrass Prairie Ecosystem 总被引:3,自引:0,他引:3
Xuhui Zhou Xiaozhong Liu Linda L. Wallace Yiqi Luo 《植物学报(英文版)》2007,49(3):270-281
Global temperature has been Increased by 0.6 ℃ over the past century and is predicted to Increase by 1.4-5.8 ℃ by the end of this century. It is unclear what impacts global warming will have on tallgrass species. In the present study, we examined leaf net photosynthetic rate (P.) and leaf respiration rate in darkness (Rd) of Aster erlcoldes (L.) Nesom, Ambrosia psllostachya DC., Helianthus mollis Lam., and Sorghastrum nutans (L.) Nash In response to experimental warming in a tallgrass prairie ecosystem of the Great Plains, USA, in the autumn (fall) of 2000 and through 2001. Warming has been Implemented with infrared heaters since 21 November 1999. The P. increased significantly In spring, decreased in early fall, and did not change in summer and late fall in the four species under warming compared with control. The Rd of the four species increased significantly until mid-summer and then did not change under warming. Measured temperature-response curves of P. showed that warming Increased the optimum temperature of P. (Topt) by 2.32 and 4.59 ℃ for H. mollis and S. nutans, respectively, in August, whereas there were no changes in May and September, and A. ericoldes and A. psllostachya also showed no changes in any of the 3 months. However, P. at optimum temperature (Popt) showed downregulation in September and no regulation in May and August for all four species. The temperature-response curves of Rd Illustrate that the temperature sensitivity of Rd, Q10, was lower in the warmed plots compared with the control plots, except for A. ericoides in August, whereas there were no changes In May and September for all four species. The results of the present study indicate that photosynthetic and respiratory acclimation varies with species and among seasons, occurring In the mid-growing season and not in the early and late growing seasons. 相似文献
995.
采用LI-6400便携式光合测定系统(Li-Cor Inc., USA)对显脉金花茶光合特性进行研究。结果表明:(1)在夏季,显脉金花茶叶片的Pn日变化呈单峰曲线,最高峰出现在中午11:00。其最大净光合速率(Pmax)为3.81 μmol·m-2·s-1、光饱和点(LSP)为459.9 μmol·m-2·s-1、光补偿点(LCP)为6.9 μmol·m-2·s-1。显脉金花茶的光饱和点和光补偿点都比较低,表明其是一种阴生植物。(2)在控制光照强度和温度的条件下,CO2浓度小于800 μmol·mol-1,Pn几乎呈直线上升,升高CO2浓度可使显脉金花茶的净高合速率增大,提高了叶片对光能的利用率。其叶片CO2饱和点(CSP)大约在1 200 μmol·mol-1左右,CO2的补偿点(Г*)为70.1 μmol·mol-1,最大羧化速率(Vcmax)为17.5 μmol·m-2·s-1,最大电子传递速率(Jmax)为40 μmol·m-2·s-1。 相似文献
996.
According to the instantaneous growth rate (dN/dt) of E. coli CVCC249 growing in batch culture, the entire growth progress was distinguished into four phases: accelerating growth phase,
constant growth phase, decelerating growth phase and declining phase, in each of which obvious variation in physiological
and biochemical properties was detected, including total DNA, total protein, and MTT-dehydrogenase activity, etc., that led
to difference in their antibiotic susceptivity. Antibiotic susceptivity of the population sampled from each phase was tested
by Concentration-killing Curve (CKC) approach following the formula N=N
0/{1+exp[r·(x-BC
50)]}, showing as normal distribution at the individual cell level for an internal population, in which the median bactericidal
concentration BC
50 represents the mean level of susceptivity, while the bactericidal span BC
1−99=(2lnN
0)/r indicates the variation degree of the antibiotic susceptivity. Furthermore, tested by CKC approach, the antibiotic susceptivity
of E. coli CVCC249 population in each physiological phase to gentamicin or enoxacin was various: susceptivity of the population in the
constant growth phase and declining phase all increased compared with that in the accelerating growth phase for gentamicin
but declined for enoxacin. The primary investigations revealed that the physiological phase should be taken into account in
the context of antibiotic susceptivity and research into antimicrobial mechanism. However there are few reports concerned
with this study. Further research using different kinds of antibiotics with synchronized continuous culture of different bacterial
strains is required.
Supported by the Natural Science Foundation of Shandong Province, China (Grant No. Y2005C58), the Natural Key Technology R&D
Program of China (Grant No. 2006BAK02A03-6) and the Youth Scientific Research Foundation of Shandong Academy of Agricultural
Science (2005YQ035) 相似文献
997.
Liang Zhao Shixiao Xu Yingnian Li Yanhong Tang Xinquan Zhao Song Gu Mingyuan Du Guirui Yu 《生物学前沿》2007,2(3):324-332
Carbon dioxide fluxes of Kobresia humilis and Potentillafruticosa shrub meadows,two typical ecosystems in the Qinghai-Tibet Plateau,were measured by eddy covariance technology and the data collected in August 2003 were employed to analyze the relations between carbon dioxide fluxes and environmental factors of the ecosystems.August is the time when the two ecosystems reach their peak leaf area indexes and stay stable,and also the period when the net carbon absorptions of Kobresia humilis and Potentilla photo flux densities (PPFD),the carbon dioxide-uptake rate of the Kobresia humilis meadow is higher than that of the Potentilla fruticosa shrub meadow;where the PPFD are rates of the two ecosystems declined as air temperature increased,but the carbon dioxide uptake rate of the Kobresia humilis meadow decreased more quickly (-0.086) than that of the Potentilla fruticosa shrub meadow (-0.016).Soil moistures exert influence on the soil respirations and this varies with the vegetation type.The daily carbon dioxide absorptions of the ecosystems increase with increased diurnal temperature differences and higher diurnal temperature differences result in higher carbon dioxide exchanges.There exists a negative correlation between the vegetation albedos and the carbon dioxide fluxes. 相似文献
998.
Seals may delay costly physiological processes (e.g. digestion) that are incompatible with the physiological adjustments to diving until after periods of active foraging. We present unusual profiles of metabolic rate (MR) in grey seals measured during long-term simulation of foraging trips (4-5 days) that provide evidence for this. We measured extremely high MRs (up to almost seven times the baseline levels) and high heart rates during extended surface intervals, where the seals were motionless at the surface. These occurred most often during the night and occurred frequently many hours after the end of feeding bouts. The duration and amount of oxygen consumed above baseline levels during these events was correlated with the amount of food eaten, confirming that these metabolic peaks were related to the processing of food eaten during foraging periods earlier in the day. We suggest that these periods of high MR represent a payback of costs deferred during foraging. 相似文献
999.
Valance D Desprès G Boissy A Mignon-Grasteau S Constantin P Leterrier C 《Genes, Brain & Behavior》2007,6(4):339-346
This study investigated whether genetic selection on a divergent behavioural trait of fearfulness (tonic immobility duration) was related to changes in the nervous control of the heart. Quail selected for either long or short tonic immobility (LTI or STI, respectively) duration was compared with an unselected control line (CTI). The autonomic control of the heart was assessed by heart rate variability analysis and pharmacological blockades. Quail were surgically fitted with a telemetric device. Heart rate before injection did not differ between the three lines. The vagal-sympathetic effect (VSE) at rest differed significantly from 1 in CTI and STI quail, suggesting that parasympathetic activity was dominant. In LTI quail, VSE did not differ from 1, suggesting a balance between parasympathetic and sympathetic activities. The intrinsic heart rate reached after the successive injections of propranolol and atropine did not differ between lines and was higher than the heart rate at rest in STI, which was in line with results of VSE at rest. After atropine injection, the sympathetic activity indicated by the low-frequency power was lower in CTI than in the two selected quail. After propranolol injection, the parasympathetic activity indicated by the root of the mean squares of successive differences and the high-frequency power was higher in STI than in CTI and LTI quail. Selection on tonic immobility duration thus appears to be associated with changes in the sympathovagal control of the heart, which may influence behavioural responses to stressful situations. 相似文献
1000.
Thomas Kastner Sarah Matej Matthew Forrest Simone Gingrich Helmut Haberl Thomas Hickler Fridolin Krausmann Gitta Lasslop Maria Niedertscheider Christoph Plutzar Florian Schwarzmüller Jrg Steinkamp Karl-Heinz Erb 《Global Change Biology》2022,28(1):307-322
Land use has greatly transformed Earth's surface. While spatial reconstructions of how the extent of land cover and land-use types have changed during the last century are available, much less information exists about changes in land-use intensity. In particular, global reconstructions that consistently cover land-use intensity across land-use types and ecosystems are missing. We, therefore, lack understanding of how changes in land-use intensity interfere with the natural processes in land systems. To address this research gap, we map land-cover and land-use intensity changes between 1910 and 2010 for 9 points in time. We rely on the indicator framework of human appropriation of net primary production (HANPP) to quantify and map land-use-induced alterations of the carbon flows in ecosystems. We find that, while at the global aggregate level HANPP growth slowed down during the century, the spatial dynamics of changes in HANPP were increasing, with the highest change rates observed in the most recent past. Across all biomes, the importance of changes in land-use areas has declined, with the exception of the tropical biomes. In contrast, increases in land-use intensity became the most important driver of HANPP across all biomes and settings. We conducted uncertainty analyses by modulating input data and assumptions, which indicate that the spatial patterns of land use and potential net primary production are the most critical factors, while spatial allocation rules and uncertainties in overall harvest values play a smaller role. Highlighting the increasing role of land-use intensity compared to changes in the areal extent of land uses, our study supports calls for better integration of the intensity dimension into global analyses and models. On top of that, we provide important empirical input for further analyses of the sustainability of the global land system. 相似文献