doi: 10.1111/j.1741‐2358.2012.00658.x Survival analysis of mandibular complete dentures with acrylic‐based resilient liners Objective: The purpose of this long‐term randomised controlled trial was to compare the longevity of dentures constructed using a conventional acrylic resin (CAR) to that of dentures constructed using an acrylic‐based resilient liner (ARL). Materials and methods: The follow‐up study was essentially carried out by annual telephone calls to each of the 67 participants. The Kaplan–Meier method and life‐table analysis were used for univariate analyses. The Cox proportional‐hazards test was used as a final model for statistically adjusting predictor variables such as sex, clinician type, mandibular denture type and age at denture delivery. Results: The denture type was likely to affect the survival time of the dentures, while the sex and clinician type were not. The group using acrylic‐based resilient denture liners had twice the risk of having shorter denture‐survival times than those using conventional acrylic resin dentures. Younger participants were likely to have a reduced risk of having shorter denture‐survival times than older participants. Conclusion: We conclude that mandibular complete dentures constructed using ARL are twice as likely as dentures constructed using CAR to have shorter denture survival times, mainly because of material deterioration. 相似文献
doi: 10.1111/j.1741‐2358.2010.00428.x In vivo biofilm formation on a soft denture liner in elderly patients with controlled diabetes Objectives: This in vivo study evaluated the influence of controlled diabetes on biofilm formation on a soft denture liner in elderly patients. Background: Soft denture lining materials are more susceptible to microbial colonisation than denture base acrylic resins. Especially in the elderly, several predisposing factors may accumulate leading to an increased probability of biofilm development that may result in candidiasis, a significant clinical oral disease. Materials and methods: Volunteers wearing complete dentures were divided into two groups (n = 20): diabetic patients with controlled glycaemia, and healthy patients. In both groups, a silicone‐based soft liner was placed in a recess created at the base of the maxillary dentures. Subjects cleaned the prosthesis three times a day. Biofilm formed on the liner was quantified at various time points (baseline, two, four and six weeks). Data were analysed by two‐way repeated measures anova and Tukey’s test (α = 0.05). Results: There was no statistical difference in biofilm formation for any of the time points between controlled diabetes patients and healthy patients. Conclusion: The results suggest that the control of diabetes in elderly patients provides the same levels of biofilm formation when compared to healthy individuals. 相似文献
The use of sand-bentonite mixtures as liner materials for waste disposal is very common. In the laboratory, this study investigated hydraulic conductivities of such mixtures at different hydraulic pressure (hydraulic gradient), dry unit weights, and bentonite contents. The bentonite content and the dry unit weight of the samples were both important factors, significantly affecting the hydraulic conductivity of the liner material. A bentonite content of 5% was found to be sufficient in reaching a hydraulic conductivity under 10?9 m/s, when the liner material was compacted under near optimum moisture content. Nevertheless, hydraulic conductivity was found to increase with hydraulic pressures, especially for the 5% bentonite mixtures subjected to pressure above 40 kPa, suggesting some degree of internal erosion (washing out of particles).
Therefore, this paper discuses the influence of internal erosion of the mixtures under a given hydraulic gradient, on the final value of k. The internal erosion of the tested mixtures was found to be influenced mainly by porosity, which can be reduced by properly selecting the sand particle size distribution and the bentonite percentage. Furthermore, this study proposed an empirical expression to predict the risk of internal erosion in the sand-bentonite mixtures, and therefore of k being higher than planned. This expression can be used for designing bentonite content and compaction to achieve very low permeability. 相似文献
Despite technological developments and improved liner-material applications, heavy metals in landfill leachate still penetrate the soil profile, polluting the soil and ground-water. An alternative approach therefore must be explored to reduce heavy-metal migration in soil-bentonite landfill liners. By considering the interaction of different heavy metals and their synergetic and antagonistics behaviors, such an approach could be developed. Low mobility metals such as Cu2+, and Pb2+ inhibit the adsorption of Cd2+ which is a moderate-mobility metal and Cu2+ sorption is decreased by the presence of Zn2+ and Cd2+. Therefore, Zn2+, a low-mobility metal, cannot be grouped with Cu2+. This way, four compatible metal groups have been identified: (1) low mobility: Pb2+, Cu2+, and Ag, (2) low mobility: Zn2+ and Cr3+; (3) moderate mobility: As2+, Fe2+, and Ni2+; (4) high mobility: Cd2+ and Hg2+. Cd2+ with a moderate mobility pattern is synergetic to Fe2+ and is more mobile with Ni2+. Therefore, Cd2+ is separated from the moderate-mobility group and is consigned with Hg, a high-mobility metal. The liner materials suitable for Hg2+ are assumed to be suitable for Cd2+ as well. Based on this concept, and to reduce heavy metal mobility, wastes should be segregated on compatibility basis according to their heavy metal contents before being disposed in different individual compartments. For wastes containing several incompatible heavy metals, sorting should be based on the heavy-metal with the highest concentration. Another solution is the manufacturing of products using compatible heavy metal combinations and then labeling them accordingly. Such waste segregation and landfill compartmentalization lowers risks of groundwater contamination and liner cost. 相似文献
Summary A method is described for the monolayer cultivation of primary cell suspensions and established cell lines directly in carbon-coated
BEEM capsules. BEEM capsules are routinely employed by electron microscopists in tissue embedding procedures; growing monolayer
cultures directly on the lids of inverted BEEM capsules presents the obvious advantage of maintaining cell to cell to substratum
contacts with a minimum of stress and damage in the preparative steps for electron microscopy.
This work was supported by grant AM 17631 from the National Institute of Arthritis, Metabolism, and Digestive Diseases, grant
CA 11339 from the National Cancer Institute. The Jackson Laboratory is fully accredited by the American Association for Accreditation
of Laboratory Animal Care. 相似文献
doi:10.1111/j.1741‐2358.2009.00329.x Experiments on in vivo biofilm formation and in vitro adhesion of Candida species on polysiloxane liners Objectives: Microorganisms may colonise polysiloxane soft liners leading to bio‐deterioration. The aim of this study was to investigate in vitro adhesion and in vivo biofilm formation of Candida species on polysiloxane surfaces. Methods: The materials used in this study were Molloplast B, GC Reline soft, Mollosil Plus, Silagum Comfort and Palapress Vario. The in vitro retention of clinical isolates of Candida albicans to the relining and denture‐base materials by microscopic (scanning electron microscopy, SEM), conventional culturing methods and antimicrobial properties of these materials were studied. Candida found on materials and mucosa following long‐term use were identified and quantified, and biofilms covering the surfaces were investigated by SEM. Results: There was a significant decrease in the number of cells attached in vitro to saliva‐coated surfaces compared with non‐treated surfaces. An oral Candida carriage of 78% was found. Candida albicans, C.glabrata, C.intermedia and C. tropicalis were identified. In vivo biofilm formation on the liners appeared as massive colonisation by microorganisms. Conclusions: The results of the in vitro experiments suggest that salivary film influences early colonisation of different C. albicans strains. The film layer also minimises the differences among different strains. The Candida carriage of these patients was similar to denture‐wearing patients without soft liners. 相似文献