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871.
The sea anemone Haliplanella luciae (Cnidaria, Anthozoa) detects chemical and mechanical stimuli from prey. Hair bundle mechanoreceptors on the tentacles participate
in regulating discharge of microbasic p-mastigophore nematocysts. Properly stimulated hair bundles sensitize the anemone
to discharge nematocysts into objects that contact the tentacles. The hair bundle mechanoreceptors are composed of stereocilia
derived from a multicellular complex. This complex consists of a single sensory neuron surrounded by two to four supporting
cells. The mechanoreceptor is similar in many ways to vertebrate hair cells of the acousticolateralis system. However, anemone
hair bundles are adjustable in structure and responsiveness according to the activity of two different chemoreceptors. One
chemoreceptor binds N -acetylated sugars and the other binds amino compounds including proline. N -acetylated sugars induce lengthening of the hair bundle and a downward shift in frequencies that elicit maximal discharge
of microbasic p-mastigophore nematocysts. Furthermore, N -acetylated sugars shift maximal discharge to smaller amplitude vibrations. Thus, N -acetylated sugars likely tune hair bundles so that small, swimming zooplankton stimulate maximal discharge. Proline leaks
into the seawater from the hemolymph of wounded prey. Proline induces shortening of the hair bundle and shifts maximal discharge
of nematocysts to higher frequencies and to larger amplitude vibrations. Thus, proline likely tunes hair bundles so that small,
wounded, prey stimulate maximal discharge of nematocysts as they struggle to escape. Thus, suitably sized prey stimulate maximal
discharge of microbasic p-mastigophore nematocysts upon first contacting the anemone tentacle and again upon attempting to
escape. 相似文献
872.
Detailed benthic foraminiferal analyses performed on the Holocene subsurface deposits of modern Po Delta evidenced a complex palaeogeographic evolution. Hierarchical R- and Q-mode cluster analyses allowed to distinguish four assemblages indicative of different marine environments and sub-environments. Temporal and spatial distribution patterns of benthic foraminifers reflect changes in Po River discharge during delta evolution. The capability of foraminiferal assemblages to track nutrients and sediment supply oscillations permitted to recognize four main evolutionary phases (A–D), which took place after the maximum marine transgression (ca. 5500 cal yr BP). 相似文献
873.
Summary In the telotrophic ovariole of Dysdercus intermedius the intercellular transport consists of different subsystems. Microinjection of FITC-labeled slowly diffusing proteins with opposite electrical net charges and of mitochondria was used to study the translocation of macromolecules and organelles. a) By intracellular measurements a voltage gradient of about 4 mV between the tropharium as the more negative side and the previtellogenic oocytes could be demonstrated. b) After injection into the tropharium negatively charged proteins migrated according to the electropotential gradient via the trophic cords into the oocytes. Positively charged proteins, however, were retained in the tropharium. c) After injection into previtellogenic oocytes both negatively and positively charged proteins moved into the trophic cords. Thus, the effectiveness of the electropotential gradient on the distribution of charged proteins is more pronounced from the tropharium side. d) Mitochondria microinjected into the trophic core were probably aligned along microtubules and translocated towards the trophic cords. — These results suggest that in the telotrophic bug ovariole a number of intercellular transport subsystems contribute to provide previtellogenic oocytes with nurse cells products. An electrophoretic transport mechanism for soluble proteins acting especially within the tropharium and a microtubule-associated transport for mitochondria could be evidenced. 相似文献
874.
Prevention of biofilm formation by polymer modification 总被引:3,自引:0,他引:3
Bacterial biofilm formation on synthetic polymers plays an important role in industry and in modern medicine, leading, for example, to difficult-to-treat infections caused by colonized foreign bodies. Prevention of biofilm formation is a necessary step in the successful prophylaxis of such infections. One approach is to inhibit bacterial adherence by polymer surface modification. We have investigated polymer modification by glow discharge treatment in order to study the influence of the modified surface on bacterial adherence. Surface roughness, surface charge density and contact angles of the modified polymers were determined and related to the adherence ofStaphylococcus epidermidis KH6. Although no influence of surface roughness and charge density on bacterial adherence was noticed, a correlation between the free enthalpy of adhesion (estimated from contact angle measurements) and adherence was observed. There seems to exist a certain minimum bacterial adherence, independent of the nature of the polymer surface. Modified polymers with negative surface charge allow for bacterial adherence close to the adherence minimum. These polymers could be improved further by the ionic bonding of silver ions to the surface. Such antimicrobial polymers are able to prevent bacterial colonization, which is a prerequisite for biofilm formation. It is suggested that modification of polymers and subsequent surface coupling of antimicrobials might be an effective approach for the prevention of bacterial biofilm formation. 相似文献
875.
Richard G. Dudley Randall D. Quintrell Gary S. Beisser 《Environmental Biology of Fishes》1980,5(3):235-242
Synopsis Changes in electrofishing catch rates downstream from Clark Hill Reservoir were only mildly affected by addition of oxygen to the hypolimnion waters prior to discharge in spite of increases in oxygen concentration. Changes in abundance and distribution of six major species were detectable and beneficial effects undoubtedly occur, but the overall benefit of oxygenation, at least at Clark Hill Dam, is questionable. At other dams with a more pronounced and prolonged oxygen-poor period, oxygenation may be worthwhile. 相似文献
876.
Pauli J. M. Snoeijs 《植被学杂志》1990,1(5):599-608
Abstract. In order to forecast consequences of climatic changes for littoral algae in coastal ecosystems, the effects of temperature increase on spring bloom dynamics of epilithic diatom communities were studied in two ways: (1) Communities were compared from sites receiving different amounts of cooling water discharge from a nuclear power plant. (2) Communities from the exceptionally warm spring of 1989 were compared with those from the same sites in the preceding normal years. The studies were carried out in and around the Forsmark Biotest Basin, an artificial waterbody that receives brackish cooling water from the Forsmark nuclear power plant on the Swedish east coast. Species composition and biomass data from 200 epilithic diatom samples taken in the period January-May from 1983 to 1989 were analysed. Multiple regression analysis was used to show the responses of diatom cover, community diversity and abundances of individual taxa to water temperature and other environmental factors. Constrained ordination (CCA) was used to display the relationship of overall community composition to environment. Increased water temperature resulted in higher biomass through a chain of ecological effects. Strong reduction of ice cover was crucial in this chain, resulting in reduced loss of diatom cells by reduced abrading and higher primary production by higher availability of light, nutrients and substrate. The conclusion is that large blooms of fast-growing epilithic diatoms in large colonies can occupy the niche that emerges when the ice-free season is prolonged in the northern Baltic Sea and areas similar in salinity and climatic conditions. Dramatic species shifts may only be expected if the winter ice cover is totally absent. 相似文献
877.
Gayathri S. Prabhu Keerthana Prasad Mohandas Rao K.G. Kiranmai S. Rai 《Saudi Journal of Biological Sciences》2021,28(4):2396-2407
IntroductionThe aim of this study was to assess the efficacy of choline and DHA or exposure to environmental enrichment in obese adult and aging rats on alterations in body mass index, serum lipid profile and arterial wall changes, despite stopping high fat diet consumption and interventions during adulthood.Methods21 day old male Sprague Dawley rats were assigned as Experiment-1 & 2 - PND rats were divided into 4 groups with interventions for 7 months (n = 8/group). NC– Normal control fed normal chow diet; OB- Obese group, fed high fat diet; OB + CHO + DHA- fed high fat diet and oral supplementation of choline, DHA. OB + EE- fed high fat diet along with exposure to enriched environment .Experiment-2 had similar groups and interventions as experiment 1 but for next 5 months were fed normal chow diet without any interventions. Body mass index was assessed and blood was analyzed for serum lipid profile. Common Carotid Artery (CCA) was processed for Haematoxylin and eosin, Verhoff Vangeison stains. Images of tissue sections were analyzed and quantified using image J and tissue quant software.ResultsIn experiment.1, mean body mass index (p < 0.001), serum lipid profile (p < 0.01), thickness of tunica intima (p < 0.05), tunica media (p < 0.01) and percentage of collagen fibers (p < 0.01) of CCA were significantly increased in OB compared to NC. These were significantly attenuated in OB + CHO + DHA and OB + EE compared to OB. In experiment.2, mean body mass index (p < 0.01), serum lipid profile (p < 0.05) and thickness of tunica media of CCA (p < 0.01) were significantly increased in OB compared to NC. In OB + CHO + DHA and OB + EE, significant attenuation was observed in mean body mass index and mean thickness of tunica media compared to same in OB.ConclusionAdult obesity has negative impact on body mass index, serum lipid profile and arterial wall structure that persists through aging. Supplementation of choline and DHA or exposure to enriched environment during obesity attenuates these negative impacts through aging. 相似文献
878.
《Journal of lipid research》2022,63(11):100283
Intrauterine growth restriction (IUGR) predisposes to chronic kidney disease via activation of proinflammatory pathways, and omega-3 PUFAs (n-3 PUFAs) have anti-inflammatory properties. In female rats, we investigated 1) how an elevated dietary n-3/n-6 PUFA ratio (1:1) during postnatal kidney development modifies kidney phospholipid (PL) and arachidonic acid (AA) metabolite content and 2) whether the diet counteracts adverse molecular protein signatures expected in IUGR kidneys. IUGR was induced by bilateral uterine vessel ligation or intrauterine stress through sham operation 3.5 days before term. Control (C) offspring were born after uncompromised pregnancy. On postnatal (P) days P2–P39, rats were fed control (n-3/n-6 PUFA ratio 1:20) or n-3 PUFA intervention diet (N3PUFA; ratio 1:1). Plasma parameters (P33), kidney cortex lipidomics and proteomics, as well as histology (P39) were studied. We found that the intervention diet tripled PL-DHA content (PC 40:6; P < 0.01) and lowered both PL-AA content (PC 38:4 and lyso-phosphatidylcholine 20:4; P < 0.05) and AA metabolites (HETEs, dihydroxyeicosatrienoic acids, and epoxyeicosatrienoic acids) to 25% in all offspring groups. After ligation, our network analysis of differentially expressed proteins identified an adverse molecular signature indicating inflammation and hypercoagulability. N3PUFA diet reversed 61 protein alterations (P < 0.05), thus mitigating adverse IUGR signatures. In conclusion, an elevated n-3/n-6 PUFA ratio in early diet strongly reduces proinflammatory PLs and mediators while increasing DHA-containing PLs regardless of prior intrauterine conditions. Counteracting a proinflammatory hypercoagulable protein signature in young adult IUGR individuals through early diet intervention may be a feasible strategy to prevent developmentally programmed kidney damage in later life. 相似文献
879.
《Endocrine practice》2021,27(6):561-566
ObjectiveThe primary objective of this study was to examine the patient comprehension of diabetes self-management instructions provided at hospital discharge as an associated risk of readmission.MethodsNoncritically ill patients with diabetes completed patient comprehension questionnaires (PCQ) within 48 hours of discharge. PCQ scores were compared among patients with and without readmission or emergency department (ED) visits at 30 and 90 days. Glycemic measures 48 hours preceding discharge were investigated. Diabetes Early Readmission Risk Indicators (DERRIs) were calculated for each patient.ResultsOf 128 patients who completed the PCQ, scores were similar among those with 30-day (n = 31) and 90-day (n = 54) readmission compared with no readmission (n = 72) (79.9 ± 14.4 vs 80.4 ± 15.6 vs 82.3 ± 16.4, respectively) or ED visits. Clarification of discharge information was provided for 47 patients. PCQ scores of 100% were achieved in 14% of those with and 86% without readmission at 30 days (P = .108). Of predischarge glycemic measures, glycemic variability was negatively associated with PCQ scores (P = .035). DERRIs were significantly higher among patients readmitted at 90 days but not 30 days.ConclusionThese results demonstrate similar PCQ scores between patients with and those without readmission or ED visits despite the need for corrective information in many patients. Measures of glycemic variability were associated with PCQ scores but not readmission risk. This study validates DERRI as a predictor for readmission at 90 days. 相似文献