Reactive strength index-modified: reliability,between group comparison,and relationship between its associated variables

To investigate and compare the reliability of reactive strength index-modified (RSImod) and its associated variables (jump height [JH] and [time to take-off]) 20 combat fighters and 18 physically active men participated in this study. They visited the laboratory three times; firstly, for jump familiarization and two sessions for test-retest (2–7 days apart). For both groups, the between-day changes in performance were trivial to small (≤ 1.1%). The coefficient of variation (CV) comparisons (i.e. CV ratio) demonstrated that combat athletes had a lower test-retest variation for RSImod (0.87) and JH (0.80) than non-athletes. Combat athletes demonstrated a greater JH than physically active men (0.43 vs 0.37; p = 0.03, g = 0.73), but small and non-significant differences were observed for RSImod (0.60 vs 0.55; p = 0.24, g = 0.38) and TTT (0.70 vs 0.72; p = 0.32, g = 0.33). RSImod was more positively correlated with JH (r = 0.75–0.87; p < 0.001) than negatively correlated with TTT (r = 0.45–0.54; p < 0.001). This study suggests that RSImod is a reliable variable obtained during CMJ testing in combat athletes and physically active men, with scores being slightly better for combat athletes. In terms of performance, combat athletes jumped higher than physically active men, but no differences in RSImod or TTT were observed. Lastly, RSImod was more strongly related to JH than TTT, and this was more evident in athletes than nonathletes. This indicates that the combat athletes were able to better utilize their (equal) time spent jumping (higher), possibly via greater utilization of the stretch shortening cycle, faster or more optimal motor unit recruitment, or an array of other factors.     

Jumping ability: A theoretical integrative approach

A theoretical integrative approach is proposed to understand the overall mechanical characteristics of lower extremities determining jumping ability. This approach considers that external force production during push-off is limited by mechanical constraints imposed by both movement dynamics and force generator properties, i.e. lower extremities characteristics. While the velocity of the body depends on the amount of external force produced over the push-off, the capabilities of force production decrease with increasing movement velocity, notably for force generators driven by muscular contraction, such as lower extremities of large animals during jumping from a resting position. Considering the circular interaction between these two mechanical constraints, and using simple mathematical and physical principles, the proposed approach leads to a mathematical expression of the maximal jump height an individual can reach as a function of only three integrative mechanical characteristics of his lower extremities: the maximal force they can produce (), the maximal velocity at which they can extend under muscles action () and the distance of force production determined by their usual extension range (h_PO). These three integrative variables positively influence maximal jump height. For instance in humans, a 10% variation in , or h_PO induces a change in jump height of about 10-15%, 6-11% and 4-8%, respectively. The proposed theoretical approach allowed to isolate the basic mechanical entities through which all physiological and morphological specificities influence jumping performance, and may be used to separate the very first macroscopic effects of these three mechanical characteristics on jumping performance variability.     

The Drosophila wings apart Gene Anchors a Novel,Evolutionarily Conserved Pathway of Neuromuscular Development

wings apart (wap) is a recessive, semilethal gene located on the X chromosome in Drosophila melanogaster, which is required for normal wing-vein patterning. We show that the wap mutation also results in loss of the adult jump muscle. We use complementation mapping and gene-specific RNA interference to localize the wap locus to the proximal X chromosome. We identify the annotated gene CG14614 as the gene affected by the wap mutation, since one wap allele contains a non-sense mutation in CG14614, and a genomic fragment containing only CG14614 rescues the jump-muscle phenotypes of two wap mutant alleles. The wap gene lies centromere-proximal to touch-insensitive larva B and centromere-distal to CG14619, which is tentatively assigned as the gene affected in introverted mutants. In mutant wap animals, founder cell precursors for the jump muscle are specified early in development, but are later lost. Through tissue-specific knockdowns, we demonstrate that wap function is required in both the musculature and the nervous system for normal jump-muscle formation. wap/CG14614 is homologous to vertebrate wdr68, DDB1 and CUL4 associated factor 7, which also are expressed in neuromuscular tissues. Thus, our findings provide insight into mechanisms of neuromuscular development in higher animals and facilitate the understanding of neuromuscular diseases that may result from mis-expression of muscle-specific or neuron-specific genes.     

JUMP LANDING CHARACTERISTICS IN ELITE SOCCER PLAYERS WITH CEREBRAL PALSY

The aim of the present study was to analyse the parameters that characterize the vertical ground reaction force during the landing phase of a jump, and to determine the relationship among these parameters in elite soccer players with cerebral palsy (CP). Thirteen male members of the Spanish national soccer team for people with CP (mean age: 27.1 ± 4.7 years) volunteered for the study. Each participant performed three counter movement jumps. The characteristics of the first peak of the vertical ground reaction force during the landing phase of a jump, which corresponds to the forefoot contact with the ground, were similar to the results obtained in previous studies. However, a higher magnitude of rearfoot contact with the ground (F2) was observed in participants with CP than in participants without CP. Furthermore, a significant correlation between F2 magnitude and the elapsed time until its production (T2) was not observed (r = -0.474 for p = 0.102). This result implies that a landing technique based on a delay in the production of F2 might not be effective to reduce its magnitude, contrary to what has been observed in participants without CP. The absence of a significant correlation between these two parameters in the present study, and the high magnitude of F2, suggest that elite soccer players with CP should use footwear with proper cushioning characteristics.     

Analytical and multibody modeling for the power analysis of standing jumps

Two methods for the power analysis of standing jumps are proposed and compared in this article. The first method is based on a simple analytical formulation which requires as input the coordinates of the center of gravity in three specified instants of the jump. The second method is based on a multibody model that simulates the jumps processing the data obtained by a three-dimensional (3D) motion capture system and the dynamometric measurements obtained by the force platforms. The multibody model is developed with OpenSim, an open-source software which provides tools for the kinematic and dynamic analyses of 3D human body models. The study is focused on two of the typical tests used to evaluate the muscular activity of lower limbs, which are the counter movement jump and the standing long jump. The comparison between the results obtained by the two methods confirms that the proposed analytical formulation is correct and represents a simple tool suitable for a preliminary analysis of total mechanical work and the mean power exerted in standing jumps.     

A novel comparative method for identifying shifts in the rate of character evolution on trees

Evolutionary biologists since Darwin have been fascinated by differences in the rate of trait-evolutionary change across lineages. Despite this continued interest, we still lack methods for identifying shifts in evolutionary rates on the growing tree of life while accommodating uncertainty in the evolutionary process. Here we introduce a Bayesian approach for identifying complex patterns in the evolution of continuous traits. The method (auteur) uses reversible-jump Markov chain Monte Carlo sampling to more fully characterize the complexity of trait evolution, considering models that range in complexity from those with a single global rate to potentially ones in which each branch in the tree has its own independent rate. This newly introduced approach performs well in recovering simulated rate shifts and simulated rates for datasets nearing the size typical for comparative phylogenetic study (i.e., ≥64 tips). Analysis of two large empirical datasets of vertebrate body size reveal overwhelming support for multiple-rate models of evolution, and we observe exceptionally high rates of body-size evolution in a group of emydid turtles relative to their evolutionary background. auteur will facilitate identification of exceptional evolutionary dynamics, essential to the study of both adaptive radiation and stasis.     

Bayesian Nonparametric Modeling Using Mixtures of Triangular Distributions

Nonparametric modeling is an indispensable tool in many applications and its formulation in an hierarchical Bayesian context, using the entire posterior distribution rather than particular expectations, increases its flexibility. In this article, the focus is on nonparametric estimation through a mixture of triangular distributions. The optimality of this methodology is addressed and bounds on the accuracy of this approximation are derived. Although our approach is more widely applicable, we focus for simplicity on estimation of a monotone nondecreasing regression on [0, 1] with additive error, effectively approximating the function of interest by a function having a piecewise linear derivative. Computationally accessible methods of estimation are described through an amalgamation of existing Markov chain Monte Carlo algorithms. Simulations and examples illustrate the approach.     

Explosive lower limb extension mechanics: An on-land vs. in-water exploratory comparison

During a horizontal underwater push-off, performance is strongly limited by the presence of water, inducing resistances due to its dense and viscous nature. At the same time, aquatic environments offer a support to the swimmer with the hydrostatic buoyancy counteracting the effects of gravity. Squat jump is a vertical terrestrial push-off with a maximal lower limb extension limited by the gravity force, which attracts the body to the ground. Following this observation, we characterized the effects of environment (water vs. air) on the mechanical characteristics of the leg push-off. Underwater horizontal wall push-off and vertical on-land squat jumps of two local swimmers were evaluated with force plates, synchronized with a lateral camera. To better understand the resistances of the aquatic movement, a quasi-steady Computational Fluid Dynamics (CFD) analysis was performed. The force-, velocity- and power-time curves presented similarities in both environments corresponding to a proximo-distal joints organization. In water, swimmers developed a three-step explosive rise of force, which the first one mainly related to the initiation of body movement. Drag increase, which was observed from the beginning to the end of the push-off, related to the continuous increase of body velocity with high values of drag coefficient (C_D) and frontal areas before take-off. Specifically, with velocity, frontal area was the main drag component to explain inter-individual differences, suggesting that the streamlined position of the lower limbs is decisive to perform an efficient push-off. This study motivates future CFD simulations under more ecological, unsteady conditions.     

Molecular systematics and biogeography of Nicrophorus in part--the investigator species group (Coleoptera: Silphidae) using mixture model MCMC

Burying beetles (Silphidae: Nicrophorus) are well-known for their biparental care and monopolization of small vertebrate carcasses in subterranean crypts. They have been the focus of intense behavioral ecological research since the 1980s yet no thorough phylogenetic estimate for the group exists. The relationships among the species, and the validity of some species, are poorly understood. Here, we infer the relationships and examine species boundaries among 50 individuals representing 15 species, primarily of the investigator species group, using a mixture-model Bayesian analysis. Two mitochondrial genes, COI and COII, were used, providing 2129 aligned nucleotides (567 parsimony-informative). The Akaike Information Criterion and Bayes Factors were used to select the best fitting model, in addition to Reversible Jump MCMC, which accommodated model uncertainty. A 21 parameter, three-partition GTR + G was the final model chosen. Despite a presumed Old World origin for the genus itself, the basal lineages and immediate outgroups of the investigator species group are New World species. Bayesian methods reconstruct the common ancestor of the investigator species group as New World and imply one later transition to the Old World with two return transitions to the New World. Prior hypotheses concerning the questionable validity of four species names, Nicrophorus praedator, Nicrophorus confusus, Nicrophorus encaustus and Nicrophorus mexicanus were tested. No evidence was found for the validity of the Nicrophorus investigator synonym N. praedator. We found evidence rejecting the species status of N. confusus (NEW SYNONYM of Nicrophorus sepultor). Weak evidence was found for the species status of N. encaustus and N. mexicanus, which are tentatively retained as valid. Our results strongly reject a recently published hypothesis that Nicrophorus interruptus (NEW STATUS as valid species) is a subspecies of N. investigator.