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283.
B. Arensburg 《Human Evolution》1996,11(2):139-145
Dental calculus has been often considered as a consequence of dietary habits, mainly related to the post Neolitic agricultural
development. The presence of fossilized bacteria in the Kebara 2 teeth, aged 60.000 years BP, and the similarity of oral pathologies
in pre and post Neolithic samples confirm the multifactorial etiology of oral diseases in general and dental calculus in particular. 相似文献
284.
P. Bauer K. Binder I. Husinski W. Kleinert W. Künzel V. Scheiber C. W. Überhuber G. Westphal F. X. Wohlzogen 《Biometrical journal. Biometrische Zeitschrift》1982,24(4):399-411
The analysis of the time dependent behavior of an irreversible all-or-none process on the basis of data from cross sectional surveys requires special methods. Assuming a pure death process three models of different degree of sophistication have been developed, mathematically analyzed and applied to one particular example: the caries attack on the permanent teeth of children. 相似文献
285.
T. T. Maske F. H. van de Sande R. A. Arthur M. C. D. N. J. M. Huysmans M. S. Cenci 《Biofouling》2017,33(8):661-675
The aim of this systematic review is to characterize and discuss key methodological aspects of in vitro biofilm models for caries-related research and to verify the reproducibility and dose-response of models considering the response to anti-caries and/or antimicrobial substances. Inclusion criteria were divided into Part I (PI): an in vitro biofilm model that produces a cariogenic biofilm and/or caries-like lesions and allows pH fluctuations; and Part II (PII): models showing an effect of anti-caries and/or antimicrobial substances. Within PI, 72.9% consisted of dynamic biofilm models, while 27.1% consisted of batch models. Within PII, 75.5% corresponded to dynamic models, whereas 24.5% corresponded to batch models. Respectively, 20.4 and 14.3% of the studies reported dose-response validations and reproducibility, and 32.7% were classified as having a high risk of bias. Several in vitro biofilm models are available for caries-related research; however, most models lack validation by dose-response and reproducibility experiments for each proposed protocol. 相似文献
286.
Masataka Oda Mie Kurosawa Hirofumi Yamamoto Hisanori Domon Shoji Takenaka Tatsuya Ohsumi Tomoki Maekawa Naoto Yamasaki Yui Furue Yutaka Terao 《Microbiology and immunology》2020,64(7):493-501
Streptococcus mutans is the main pathogen of dental caries and adheres to the tooth surface via soluble and insoluble glucans produced by the bacterial glucosyltransferase enzyme. Thus, the S. mutans glucosyltransferase is an important virulence factor for this cariogenic bacterium. Sulfated vizantin effectively inhibits biofilm formation by S. mutans without affecting its growth. In this study, less S. mutans biofilm formation occurred on hydroxyapatite discs coated with sulfated vizantin than on noncoated discs. Sulfated vizantin showed no cytotoxicity against the human gingival cell line Ca9-22. Sulfated vizantin dose-dependently inhibited the extracellular release of cell-free glucosyltransferase from S. mutans and enhanced the accumulation of cell-associated glucosyltransferase, compared with that observed with untreated bacteria. Sulfated vizantin disrupted the localization balance between cell-associated glucosyltransferase and cell-free glucosyltransferase, resulting in inhibited biofilm maturation. These results indicate that sulfated vizantin can potentially serve as a novel agent for preventing dental caries. 相似文献
287.
Abstract The proportion of non-secretors of ABH blood-group substances among Icelanders is one of the highest recorded for European countries. Dental caries prevalence is also very high. In this study of dental caries in young adults mean number of decayed, missing and filled teeth for secretors were 17.4 and for non-secretors 19.9 ( P < 0.05). A majority of patients seeking free dental treatment in the Dental School were non-secretors (62.7%) significantly more than the proportion of non-secretors in the general population (36%; P < 0.01). It is postulated that blood group substances may interfere with the adherence of Streptococcus mutants to teeth. 相似文献
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289.
The purpose of this article is to present new oral health data from Neolithic An Son, southern Vietnam, in the context of (1) a reassessment of published data on other Neolithic, Bronze, and Iron Age Southeast Asian dental series, and (2) predictions of the Neolithic Demographic Transition (NDT). To this end, frequencies for three oral conditions (caries, antemortem tooth loss, and alveolar lesions) were investigated for seven Southeast Asian adult dental series from Thailand and Vietnam with respect to time period, age‐at‐death and sex. A clear pattern of elevated rates for oral disease in the Neolithic followed by a marked improvement in oral health during the Bronze and Iron Ages was observed. Moreover, rates of caries and antemortem tooth loss for females were almost without exception higher than that for males in all samples. The consensus view among Southeast Asian bioarchaeologists that oral health did not decline with the adoption/intensification of agriculture in Southeast Asia, can no longer be supported. In light of evidence for (1) the low cariogenicity of rice; (2) the physiological predisposition of females (particularly when pregnant) to poorer oral health; and (3) health predictions of the NDT model with respect to elevated levels of fertility, the most plausible chief explanation for the observed patterns in oral health in Southeast Asia is increased levels of fertility during the Neolithic, followed by a decline in fertility during the subsequent Bronze and Iron Ages. Am J Phys Anthropol 152:197–208, 2013. © 2013 Wiley Periodicals, Inc. 相似文献