全文获取类型
收费全文 | 7610篇 |
免费 | 662篇 |
国内免费 | 299篇 |
专业分类
8571篇 |
出版年
2024年 | 30篇 |
2023年 | 202篇 |
2022年 | 315篇 |
2021年 | 427篇 |
2020年 | 398篇 |
2019年 | 615篇 |
2018年 | 463篇 |
2017年 | 257篇 |
2016年 | 284篇 |
2015年 | 447篇 |
2014年 | 504篇 |
2013年 | 671篇 |
2012年 | 351篇 |
2011年 | 398篇 |
2010年 | 276篇 |
2009年 | 353篇 |
2008年 | 304篇 |
2007年 | 311篇 |
2006年 | 318篇 |
2005年 | 246篇 |
2004年 | 220篇 |
2003年 | 201篇 |
2002年 | 190篇 |
2001年 | 107篇 |
2000年 | 113篇 |
1999年 | 77篇 |
1998年 | 71篇 |
1997年 | 48篇 |
1996年 | 55篇 |
1995年 | 32篇 |
1994年 | 29篇 |
1993年 | 31篇 |
1992年 | 16篇 |
1991年 | 23篇 |
1990年 | 25篇 |
1989年 | 19篇 |
1988年 | 16篇 |
1987年 | 21篇 |
1986年 | 10篇 |
1985年 | 22篇 |
1984年 | 15篇 |
1983年 | 7篇 |
1982年 | 11篇 |
1981年 | 15篇 |
1980年 | 11篇 |
1979年 | 7篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1967年 | 1篇 |
排序方式: 共有8571条查询结果,搜索用时 15 毫秒
1.
Comment on: Rokavec M, et al. Mol Cell 2012; 45:777-89. 相似文献
2.
3.
N. L. Klyachko 《Russian Journal of Plant Physiology》2006,53(5):702-709
This lecture is devoted to the relative contribution of various levels of regulation of the actin cytoskeleton functioning in the cell. Regulation at the levels of gene expression, mRNA and protein synthesis and stability, processes of actin polymerization/depolymerization and actin structures reorganization is briefly considered. Novel information about the pathways of signal transduction to the actin cytoskeleton with the involvement of Arp2/3 complex and RIC proteins is highlighted. 相似文献
4.
Direct somatic embryogenesis from axes of mature peanut embryos 总被引:2,自引:0,他引:2
A. H. McKently 《In vitro cellular & developmental biology. Plant》1991,27(4):197-200
Summary Plant regeneration via somatic embryogenesis was obtained in peanut (Arachis hypogaea L.) from axes of mature zygotic embryos. The area of greatest embryogenic activity was a 2-mm region adjacent to and encircling
the epicotyl. Somatic embryogenesis was evaluated on Murashige and Skoog media supplemented with a variety of auxin treatments.
Maximum production occurred on medium supplemented with 3 mg · liter−1 4-amino-3,5,6-trichloropicolinic acid. Explant cultures were transferred to half-strength medium supplemented with 1 mg ·
liter−1 gibberellic acid for somatic embryo germination and early plantlet growth. Plantlets, transferred to soil, were placed in
a greenhouse and grown to maturity. 相似文献
5.
M.A. Mena M.J. Casarejos J.A. Rodríguez-Navarro I. Rodal J.G. de Yebenes 《FEBS letters》2009,583(1):168-174
Parkin mutations produce Parkinson’s disease (PD) in humans and nigrostriatal dopamine lesions related to increased free radicals in mice. We examined the effects of NP7, a synthetic, marine derived, free radical scavenger which enters the brain, on H2O2 toxicity in cultured neurons and glia from wild-type (WT) and parkin null mice (PK-KO).NP7, 5-10 μM, prevented the H2O2 induced apoptosis and necrosis of midbrain neuronal and glial cultures from WT and PK-KO mice. NP7 suppressed microglial activation and the H2O2 induced drop-out of dopamine neurons. Furthermore, NP7 prevented the increased phosphorylation of ERK and AKT induced by H2O2. NP7 may be a promising neuroprotector against oxidative stress in PD. 相似文献
6.
7.
《Bioorganic & medicinal chemistry》2016,24(5):1014-1022
Amino derivatives of NCI8642 were synthesized and evaluated as inhibitors of DKK1/LRP6 interactions. The new inhibitors were able to activate the Wnt signaling pathway as indicated by the increased levels of β-catenin, and decrease the DKK1-induced Tau phosphorylation at serine 396. 相似文献
8.
C. S. Lin M. C. Tseng P. I. Hong W. C. Chang 《In vitro cellular & developmental biology. Plant》2006,42(4):331-335
Summary Inflorescence proliferation is a plant tissue culture technique that, can be used to obtain in vitro inflorescences year-round without the intervening development of vegetative organs. In this study, we used albino mutant
inflorescences of Dendrocalamus latiflorus as the original explant material to investigate, the effect of plant growth regulators on long-term inflorescence proliferation.
The albino inflorescences proliferated on solidified Murashige and Skoog (MS) basal medium supplemented with thidiazuron (TDZ),
and the optimal concentration for successful long-term inflorescence proliferation was 0.45 μM TDZ. A combination of α-naphthaleneacetic acid (NAA) with 0.45 μM TDZ inhibited the inflorescence proliferation. Inflorescences cultured on a TDZ-free medium supplemented with 26.82 μM NAA rooted in 21 d, vegetative shoots formed by 42 d and, in one case, flowering occurred after 63 d. The auxins 2,4-dichlorophenoxyacetic
acid (2,4-D, 4.52 μM) and pieloram (4.14 μM) induced shoot formation. The protocol described can be used to produce large numbers of mutant inflorescences within a relatively
short period of time. 相似文献
9.
10.