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91.
Rat ventral prostate nucleoli contain protein phosphokinase(s) which have distinctly different characteristics from protein phosphokinase(s) localized in the extra-nucleolar regions of the nucleus. The differences pertain to pH vs activity profiles and activation by divalent cations, utilizing dephospho-phosvitin as substrate. Lysine-rich and arginine-rich F3 histones are also phosphorylated by nucleolar protein phosphokinase(s). Phosphorylation of histones by either nucleolar or extra-nucleolar fractions was not stimulated by cAMP, whereas that of phosvitin was slightly inhibited. 相似文献
92.
James C. Tarr Michael R. Wood Meredith J. Noetzel Bruce J. Melancon Atin Lamsal Vincent B. Luscombe Alice L. Rodriguez Frank W. Byers Sichen Chang Hyekyung P. Cho Darren W. Engers Carrie K. Jones Colleen M. Niswender Michael W. Wood Nicholas J. Brandon Mark E. Duggan P. Jeffrey Conn Thomas M. Bridges Craig W. Lindsley 《Bioorganic & medicinal chemistry letters》2018,28(17):3014
93.
Forest mycorrhizal type mediates nutrient dynamics, which in turn can influence forest community structure and processes. Using forest inventory data, we explored how dominant forest tree mycorrhizal type affects understory plant invasions with consideration of forest structure and soil properties. We found that arbuscular mycorrhizal (AM) dominant forests, which are characterised by thin forest floors and low soil C : N ratio, were invaded to a greater extent by non‐native invasive species than ectomycorrhizal (ECM) dominant forests. Understory native species cover and richness had no strong associations with AM tree dominance. We also found no difference in the mycorrhizal type composition of understory invaders between AM and ECM dominant forests. Our results indicate that dominant forest tree mycorrhizal type is closely linked with understory invasions. The increased invader abundance in AM dominant forests can further facilitate nutrient cycling, leading to the alteration of ecosystem structure and functions. 相似文献
94.
Xinbo Xu Heng Liu Neil Gross Dongmin Wei Ye Qian Wenming Li Peng Wei Guojun Li Fenghua Zhang Zheng Yang Dapeng Lei Xinliang Pan 《Translational oncology》2018,11(5):1244-1250
Hypopharyngeal cancer (HC) is the most common subset of head and neck cancers. These tumors often have an aggressive clinical outcome characterized by local invasion and regional nodal metastasis. Upregulated miRNAs might be useful as biomarkers for prognosis and molecular targets for these tumors. We determined tumor expression of candidate miRNAs using microarray in 8 HC patients and validated in 372 HC patients. We also used paired tumorous and mucosal tissue to verify the miRNA expression. Log-rank test and Cox model were used to evaluate the survival; and Harrell's C-index was used to compare concordance of Cox models. Our results indicated 7 miRNAs aberrantly expressed in HC. Three of these candidate miRNAs (miRNA-4415, miRNA-200a, and miRNA-30b) were selected for further qRT-PCR validation and all of them were frequently found upregulated in HC tumors; with miR-4451 being the most differentially expressed. Moreover, high expression of miR-4451 was positively correlated with advanced tumor stage and increased mortality risk (HR: 1.6, 95% CI: 1.2–2.3; adjusted HR: 1.5, adjusted 95% CI: 1.1–2.1). Finally, significantly higher expression of miR-4451 in tumors compared to in fresh adjacent normal tissues indicates an oncogenic role of miR-4451 in this tumor. Upregulated miR-4451 in HC samples were frequently found and is significantly associated with advanced stage and poor survival of HC, which may indicate an association of this miRNA with the carcinogenesis process in this tumor site; and they could serve as a prognostic biomarker as well as help develop potential new targets for therapy. 相似文献
95.
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97.
Raul Narciso C. Guedes Srinivas Kambhampati Barry A. Dover 《Entomologia Experimentalis et Applicata》1997,84(1):49-57
The lesser grain borer (Rhyzopertha dominica (F.)) is an important pest of stored grain in many parts of the world (Paleartic, Ethiopian, Oriental, Australian, Neotropical, and Neartic regions) with the ability to fly long distances. These insects have been shown to be resistant to organophosphorus insecticides in several studies. Polyacrylamide gel electrophoresis was used to assess the genetic variability within and among eight Brazilian and seven United States populations of R. dominica and to determine how insecticide resistance may be spreading within both countries. Significant variation in allele frequency among populations was observed at all six polymorphic enzyme loci that were examined. The Brazilian and U.S. populations were genetically differentiated from one another; populations within the U.S. and those within Brazil were also differentiated from one another. The mean genetic similarity among the seven U.S. populations collected in a small region in northeast Kansas was smaller than that among eight Brazilian populations collected in a relatively large geographical area. These results are consistent with the resistance ratios to chlorpyriphos-methyl in R. dominica populations from Brazil and the U.S. and the information available concerning patterns of flight activity in this insect. 相似文献
98.
Methane emissions from three wetland habitats in the MississippiRiver deltaic plain were measured over a three year period. Fluxdata collected indicate that each habitat was a net source of methane to the atmosphere throughout the year. Average emissionfrom a Taxodium distichum / Nyssa aquatica (bald cypress / watertupelo) swamp forest was 146 ± 199 mgCH4 m-2d-1 whileemissions from a Sagittaria lancifolia (bulltongue) freshwatermarsh averaged 251 ± 188 mg CH4m-2d-1. Methane flux from a Spartina patens / Sagittaria lancifolia intermediate marsh was significantlyhigher, 912 ± 923 mg CH4m-2d-1. Seasonal variation wassignificant with emissions being higher in the late summer andearly fall. Significant diurnal emissions were observed fromthe Sagittaria lancifolia marsh site. Soil temperature (5 and 10 cm depths) was found to be significantly correlated with methaneemission from the three sites. 相似文献
99.
Temperature, but not productivity or geometry, predicts elevational diversity gradients in ants across spatial grains 总被引:2,自引:0,他引:2
Nathan J. Sanders Jean-Philippe Lessard Matthew C. Fitzpatrick Robert R. Dunn 《Global Ecology and Biogeography》2007,16(5):640-649
Aim This research aims to understand the factors that shape elevational diversity gradients and how those factors vary with spatial grain. Specifically, we test the predictions of the species–productivity hypothesis, species–temperature hypothesis, the metabolic theory of ecology and the mid-domain effects null model. We also examine how the effects of productivity and temperature on richness depend on spatial grain.
Location Deciduous forests along an elevational gradient in Great Smoky Mountains National Park, USA.
Methods We sampled 22 leaf litter ant assemblages at three spatial grains, from 1-m2 quadrats to 50 × 50 m plots using Winkler samplers.
Results Across spatial grains, warmer sites had more species than did cooler sites, and primary productivity did not predict ant species richness. We found some support for the predictions of the metabolic theory of ecology, but no support for the mid-domain effects null model. Thus, our data are best explained by some version of a species–temperature hypothesis.
Main conclusions Our results suggest that temperature indirectly affects ant species diversity across spatial grains, perhaps by limiting access to resources. Warmer sites support more species because they support more individuals, thereby reducing the probability of local extinction. Many of our results from this elevational gradient agree with studies at more global scales, suggesting that some mechanisms shaping ant diversity gradients are common across scales. 相似文献
Location Deciduous forests along an elevational gradient in Great Smoky Mountains National Park, USA.
Methods We sampled 22 leaf litter ant assemblages at three spatial grains, from 1-m
Results Across spatial grains, warmer sites had more species than did cooler sites, and primary productivity did not predict ant species richness. We found some support for the predictions of the metabolic theory of ecology, but no support for the mid-domain effects null model. Thus, our data are best explained by some version of a species–temperature hypothesis.
Main conclusions Our results suggest that temperature indirectly affects ant species diversity across spatial grains, perhaps by limiting access to resources. Warmer sites support more species because they support more individuals, thereby reducing the probability of local extinction. Many of our results from this elevational gradient agree with studies at more global scales, suggesting that some mechanisms shaping ant diversity gradients are common across scales. 相似文献
100.
In order to determine the effects of chronic exercise on the kidneys at different ages, young, adult, and old rats swam 1 hour either daily or twice a week for 10 weeks and then were killed along with unexercised controls. The kidneys were removed and sections were prepared for histometric analysis including planimetric measurements on camera lucida drawings of renal components and line sampling. With both degrees of exercise young rats showed lower kidney weight, fewer glomeruli and less medullary tissue than unexercised controls. In the adult group no significant differences were noted between exercised and unexercised rats. In old rats both degrees of exercise resulted in a loss of kidney weight and medullary and cortical mass, and a decrease in size of glomeruli while total number of glomeruli remained unchanged. Thus the effects of chronic exercise on the kidneys varied with age. Retarded kidney development occurred in young animals; a loss of renal tissue in old animals; and no change in adult animals. 相似文献