东方蝙蝠在交通噪声环境中的回声定位行为

环境噪声会降低动物声信号可探测性,是动物声信号进化的压力。为了避免人工噪声干扰,多数脊椎动物调整其叫声的频谱-时间结构,如采用延长叫声持续时间、提高频率和增加强度等策略。本研究选择回声定位声波频率范围与交通噪声频率范围相互重叠的东方蝙蝠(Vespertilio sinensis)为研究对象,在自然条件下开展实验,研究交通噪声对蝙蝠回声定位声波的影响。本实验选择交通噪声强度存在差异的两个样点,分别录制东方蝙蝠的回声定位声波,分析其结构参数。在交通噪声强度较高的样点,东方蝙蝠回声定位声波的持续时间、斜率均未显著改变,但起始频率、主频、终止频率及带宽均显著提高。结果表明,东方蝙蝠的回声定位行为在交通噪声干扰下具有明显的可塑性。     

Bioaccumulation and translocation of heavy metals by Plantago major L. grown in contaminated soils under the effect of traffic pollution

The present study was performed at a heavy-traffic affected soil to examine the efficacy of bioaccumulation and translocation potentials of heavy metals by the naturally growing weed Plantago major. Heavy metals were analyzed in soil as well as in plant below- and above-ground parts along different distances from a heavy-traffic highway. All the investigated soil heavy metals, except Cd, varied significantly, while pH and E.C had no significant difference, with increasing distance from the highway. Likewise, there was a significant decrease of heavy metals in plant below- and aboveground parts. In addition, no significant difference between most soil and root heavy metals at 20 and 100 m as well as those at 500 and 750 m distance from the highway. The bioaccumulation factor (BF) of all heavy metals, except Cd and Sr, were less than unity at most distances. However, Cd showed relative BF decline with the distance in contrast to Sr, which increases as distance from the highway increases. On the other hand, the translocation factors (TF) of Cd, Co, Cu, Pb and Zn were higher at the distances far from the highway, while that of Fe, Cr and Sr were higher near the highway. Furthermore, the enrichment factor (EF) showed small variations, among the investigated heavy metals, with varying distances from the pollution source. It was found that soil Fe, Al, Cr, Ni, Sr, V and Zn had significant positive correlation with all investigated heavy metals in P. major roots. The higher TFs of Cd, Fe and Pb in P. major shoots makes it suitable for phytoextraction from soil, while the lower ratios of Al, Mn, V, Co, Ni, Cr, Zn, Cu and Sr make it suitable for their phytostabilization. Therefore, this plant can be used as a bioindicator and biomonitor for traffic related heavy metals.     

Occupational health impacts: offshore crane lifts in life cycle assessment

Background, Aim, and Scope  The identification and assessment of environmental tradeoffs is a strongpoint of life cycle assessment (LCA). A tradeoff made in many product systems is the exchange of potential for occupational accidents with the additional use of energy and materials. Net benefits of safety measures with respect to human health are best illustrated if the consequences avoided and health impacts induced by additional emissions are assessed using commensurable metrics. Our aim is to develop a human health impact indicator for offshore crane lifts. Crane lifts are a major cause of accidents on offshore oil and gas (O & G) rigs, and health impacts from crane lift accidents should be included in comparative LCA of O & G technologies if the alternatives differ in the use of crane lifts. Materials and methods  Accident records for mobile offshore petroleum installations were used to develop an empirical occupational health indicator for crane lifts in LCA. Probabilistic parameters were introduced in the procedure, and results were calculated by Monte Carlo simulation. The disability adjusted life years (DALY) framework was used to classify health outcome. The characterization factor for offshore crane lifts was applied in three comparisons to evaluate the significance of crane lifts to human health impacts from drilling technology. Results  The mean occupational health impact per crane lift was 4.5∙10⁻⁶ DALY, with cumulative percentiles {P _2.5, P ₅₀, P _97.5} = {6.0∙10⁻⁷, 3.1∙10⁻⁶, 1.7∙10⁻⁵}. Analogously, the fatal accident frequency was described by {P _2.5, P ₅₀, P _97.5} = {7.6∙10⁻⁹, 3.9∙10⁻⁸, 2.0∙10⁻⁷}, with mean 5.6∙10⁻⁸ lives lost per crane lift. Discussion  The uncertainty in the results is caused mainly by the random nature of accidents, i.e., variability in accident frequency. Applications of the characterization factor indicate that although crane lifts may not be significant to the overall health impact of the life cycle of drilling fluids, they are important to the occupational safety of employees on offshore drilling rigs and contribute significantly to the life cycle health impact of loading technologies used to transport drilling waste to shore. A comparative LCA of technologies for loading and off-loading drilling wastes shows that a recently developed hydraulic system performs better than the traditional crane lift alternative in terms of human health impacts. Conclusions  With the availability of statistics to assess the risk of single mechanical operations, safety aspects may well be included in LCA. For the case of offshore crane lifts, the uncertainty in the characterization factor compares favorably to what is indicated for other human health impact chains. In further work of quantifying occupational health impacts in DALY using accident statistics, it is advised to see if records of non-recoverable injuries (fatalities and amputation cases) can be used to simplify the damage assessment procedure as recoverable injuries were insignificant to the total burden from crane accidents. Recommendations and perspectives  The characterization factor for crane lifts identifies contributions to life cycle health impact from loading technologies that otherwise would have been overlooked in LCA. While many contest the inclusion of occupational accidents in LCA, our results show that such impacts can be included and that their consideration adds valuable insights.     

Traffic-induced noise levels in residential urban structures using landscape metrics as indicators

Traffic noise is one of the most prominent environmental stressors in cities. It often results in cardiorespiratory diseases among urban dwellers and thus counteracts important urban health targets. Using the city of Leipzig in Germany as a case study, we show that the noise level depends on the properties of the urban structure type, determined by landscape metrics. Landscape metrics, as a type of indicator, describe potential noise in residential areas in cases in which no measured data are available, e.g., for future planning purposes. Potential noise conflict areas can be efficiently, easily and reliably detected. For each considered residential urban structure type, we computed nine different models to evaluate the noise level and the number of exposed persons in addition to 14 landscape metrics for all patches of the urban structure type. The results offer significant correlations between noise level and landscape metrics. In addition, construction height and total built area was found to reduce the noise level in neighbourhoods. These results can be adopted for other cities in Europe facing considerable structural changes in residential areas.     

Self-awareness of impairment and the decision to drive after an extended period of wakefulness

Fatigue is an increasingly noted factor in road accidents. The ability to predict and be aware of impairment in terms of driving capability is important for potential legal liability and road safety. However, to date, there have been few studies that have investigated the accuracy of individuals in predicting how safely they could drive during conditions of sleep loss. Research has demonstrated that individuals rate themselves as better than the population average in a number of domains, including driving-related skills. Therefore, this study also aimed to investigate self-ratings of predicted driving ability during extended wakefulness and compare them to ratings made of a hypothetical other person under the same conditions. Thirty-two participants remained awake for a period of 40 h. Every 2 h, they completed the Psychomotor Vigilance Task (PVT) and rated on a seven-point scale how well they thought they could drive safely, react quickly in an emergency, and stay in their own lane. They were also asked to assess how they thought someone else in their own position could drive. The participants rated their driving ability as becoming significantly poorer at the same time that their PVT performance became significantly slower. Self-ratings indicating a qualitative assessment of poorer than neutral driving occurred at 03:00 h for both the “drive safely” and “react quickly” questions, after 19 h of continuous wakefulness (starting at 08:00 h). This occurred at 05:00 h for the “keep in my lane” question. Previous studies with a similar protocol demonstrated that under these conditions, individuals exhibit a performance decrements equivalent to someone with a blood alcohol concentration of 0.05% (the legal driving limit in Australia). Participants consistently rated the ability of others to drive as poorer than their own. The main implication from this study for road safety and legal liability is that it is reasonable to focus on a person's perception of the situation, as it does align with objective reality to a certain extent. A concern in terms of road safety is potential overconfidence, indicated by rating others consistently poorer than themselves.     

Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells

Tyrosinase related protein (TRP)-1 and -2 regulate the main steps in melanin synthesis and are immune targets in skin cancer or autoimmune pigmentary disorders. We found that ionophore monensin (Mon) and the quaternary amine chloroquine (CQ) discriminate between the traffic routes of TRP-2 and TRP-1. TRP-2 N-glycan processing is interrupted by Mon between ER and trans-Golgi, whereas this process continues for TRP-1. Mature TRP-2 is diverted by CQ treatment to a degradation pathway which depends on functional vacuolar ATPases. Conversely, the subcellular distribution and stability of TRP-1 were not affected by CQ. We propose that TRP-2 is sorted and trafficked in the early secretory pathway with a cargo which does not include TRP-1; post Golgi, TRP-2 intersects the endocytic pathway following a route via early endosomes, possibly by rapid recycling from the plasma membrane. These data show that highly structural homologous glycoproteins use distinct trafficking pathways in the same cell.     

In memory of Professor Ping Wu(1957–2014)

正Sadly and miserably,our beloved and respected colleague,Prof.Ping Wu,a renowned plant biologist and the vice‐president of Zhejiang University passed away in a car accident in Hangzhou,China,in the morning of June 12,2014,aged 57.Prof.Ping Wu was born on March 27,1957,in Hangzhou,Zhejiang province,received his bachelor degree in Soil Science and Agro‐chemistry in 1982 and master degree in Plant     

COVID-19 pandemic lockdown-induced altered sleep/wake circadian rhythm,health complaints and stress among traffic police personnel in India

ABSTRACT

COVID-19 is a highly contagious disease caused by Severe Acute Respiratory Syndrome coronavirus-2, capable of high human transmission. To protect against the COVID-19 pandemic, the World Health Organization proposed intervening guidance that included movement restrictions, isolation, restriction of national and international travel or movement, and full or partial closure of organizations and institutions. Police personnel play a vital role in safeguarding the spread of COVID-19; thus, potentially causing severe stress due to increased consignment and direct exposure to infection during duty. The study aimed to determine the effect of the added stress of the COVID-19 pandemic and population lockdown on the sleep/wake 24 h rhythm of traffic police. A concise online questionnaire survey was conducted among the traffic police personnel of India. Collected data were analyzed statistically. Disorientation of working schedule, fear of being vulnerable to disease, pressure of maintaining law, and orders during lockdown increased stress level. The survey identified discontinuation of sleep, shift of mid-sleep time, increase in depression, plus stress and anxiety among traffic police personnel that affected their chronobiological milieu. Proper awareness of adequate health and safety measures, use of personnel protection equipment, regular conversation with family members, and meditation can help reduce stress during this pandemic situation.