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711.
Summary The ontogenetic apperance of pineal photo-receptors was compared with that of retinal photoreceptors in the ayu Plecoglossus altivelis and the lefteye flounder Paralichthys olivaceus, which hatched 10 days and 3 days after fertilization, respectively. Despite the disparity in incubation time, the outer segments (containing membranous lamellae) of the pineal photoreceptors first appeared from 3 to 4 days after fertilization in both species. In contrast, the outer segments of the retinal photoreceptors first became visible 5 to 6 days after fertilization, although a characteristic retinal stratification and the optic tract leaving the ganglion cell layer were already found 4 days after fertilization in both species. The functional significance of these temporal disparities and/or similarities in photoreceptor development are discussed with special reference to the timing of daily rhythmic activities during the early developmental period of the teleosts.The results were presented at the Annual Meeting of the Japanese Society of Scientific Fisheries on April 2, 1990 (Tokyo) 相似文献
712.
The signal transduction pathway controlling determination of the identity of the R7 photoreceptor in the Drosophila eye is shown to harbor high levels of naturally occurring genetic variation. The number of ectopic R7 cells induced by the
dosage-sensitive Sev
S11.1
transgene that encodes a mildly activated form of the Sevenless tyrosine kinase receptor is highly sensitive to the wild-type
genetic background. Phenotypes range from complete suppression to massive overproduction of photoreceptors that exceeds reported
effects of known single gene modifiers, and are to some extent sex-dependent. Signaling from the dominant gain-of-function
Drosophila Epidermal Growth Factor Receptor (DER-Ellipse) mutations is also sensitive to the genetic backgrounds, but there is no correlation with the effects on Sev
S11.1
. This implies that different genes and/or alleles modify the two activated receptor genotypes. The evolutionary significance
of the existence of high levels of genetic variation in the absence of normal phenotypic variation is discussed.
Received: 20 September 1997 / Accepted: 10 November 1997 相似文献
713.
I. Novales Flamarique C. W. Hawryshyn 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1998,182(3):331-341
Two families of fishes, the Cyprinidae and Salmonidae, exhibit ultraviolet sensitivity and polarization sensitivity (i.e.,
differential sensitivity to the orientation of the electric field of polarized light). Both of these families possess a square
arrangement of double cones and/or their dividing partitions in the centro-temporal retina, an area where polarization sensitivity
has been tested for and found. To correlate the presence of an ordered cone mosaic in the centro-temporal retina with polarization
sensitivity in ultraviolet-sensitive fishes, we examined the visual system of the common white sucker (Catostomus commersoni) and compared it to those of the above-mentioned families. We found that the common white sucker possesses four cone-mediated
neural mechanisms similar to those in cyprinids and salmonids, but it does not exhibit polarization sensitivity. In addition,
unlike cyprinids and salmonids, the common white sucker shows a random cone mosaic in the centro-temporal retina. These results
suggest that polarization sensitivity in ultraviolet-sensitive fishes requires an ordered double-cone mosaic in this area
of the retina.
Accepted: 19 July 1997 相似文献
714.
《Bioorganic & medicinal chemistry》2020,28(4):115214
N-terminal heptad repeat (NHR)-derived peptide (N-peptide) fusion inhibitors, which are derived from human immunodeficiency virus (HIV) envelope glycoprotein 41 (gp41), are limited by aggregation and unstable trimer conformation. However, they could function as potent inhibitors of viral infection by forming a coiled-coil structure covalently stabilized by interchain disulfide bonds. We previously synthesized N-peptides with potent anti-HIV-1 activity and high stability by coiled-coil fusion and covalent stabilization. Here, we attempted to study the effects of NHRs of chimeric N-peptides by fusing de novo coiled-coil isopeptide bridge-tethered T21 peptides of different NHR lengths. Peptides (T21N23)3 and (T21N36)3 was a more potent HIV-1 fusion inhibitor than (T21N17)3. The site of isopeptide bond formation was precisely controlled and had little influence on N-peptide properties. The N-peptide (T21N36)3, which had a similar conformation as the NHR trimer and interacted well with the C34 peptide, may be useful for screening other C-peptides and small-molecule fusion inhibitors, and for studying the interactions between the NHR trimer and C-terminal heptad repeats. 相似文献
715.
WILLIAM LOUIS STERN FLS WALTER S. JUDD FLS 《Botanical journal of the Linnean Society. Linnean Society of London》2002,139(1):1-27
Cymbideae comprise an assemblage of 28 genera nearly all of which are represented in this study. Their anatomy is relatively homogenous with the exception of Govenia , in which roots lack velamen and pseudobulb vascular bundles lack sclerenchyma, conditions that do not obtain in other genera. Marginal fibre bundles in leaves of Grammatophyllum and Porphyroglottis consist of clusters of thicker-walled, narrower, epidermis-facing fibres as well as thinner-walled, wider, mesophyll-facing fibres. This feature also occurs in some species of Maxillaria . Baculate tilosomes appear in the roots of a majority of genera in Cymbidieae, as they do in species of Maxillaria , confirming DNA analyses showing a close relationship between tribes Cymbidieae and Maxillarieae. Govenia is singled out both on anatomical and molecular grounds as being ill-placed in Cymbidieae. Cladistic analysis produces only a few tentative hypotheses of phylogenetic relationships among the 28 genera, showing that anatomical characters are of limited value in assessing affinities within this tribe. © 2002 The Linnean Society of London, Botanical Journal of the Linnean Society , 2002, 139 , 1–27. 相似文献