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Genetic structure of the Saguenay, 1852-1911: evidence from migration and isonymy matrices 总被引:1,自引:0,他引:1
The Saguenay is a region in northeastern Québec populated in the second half of the 19th century through migration from other parts of Québec. The present-day population of nearly 300,000 is the result of both immigration and high rates of intrinsic growth. This population has been of interest to geneticists because of the high incidence of certain hereditary diseases, notably spastic ataxia, tyrosinemia, agenesis of the corpus callosum, vitamin D-dependent rickets, and myotonic dystrophy. Parent-offspring migration and isonymy matrices were used to estimate random kinship using the Malécot model for six 10-year time periods from 1852-1911. Comparisons between two estimates of kinship--one from parent-offspring migration matrices (phi) and the other from isonymy (R)--and geographic distance were made using both product-moment and Mantel correlation. Comparisons of within- and between-subdivision kinship were made using nonparametric and Mantel correlation. Within-subdivision kinship from the phi matrix was also compared with kinship estimated from marriage dispensations for endogamous marriages. The estimates of random kinship from the parent-offspring matrices showed a good fit with geography. However, isonymy did not correlate well with geographic distance; and phi and R showed no correlation until the last two time periods, and the diagonal of phi did not correlate with the marriage dispensations. Examination of scatterplots of phi vs. R suggests that nonrandom migration during the process of settlement formation is responsible for the lack of correlation. While movement across space seems to be highly dependent on distance, nonrandom selection of migrants means that between-subdivision estimates of kinship based on migration are not congruent with those obtained by other methods. On the whole, genetic differentiation seems to have been low due to the high levels of movement between subdivisions and immigration. The weak dependence of genetic structure on geographic distances in the present population is demonstrated by mapping the geographic distribution of cases of three recessively inherited diseases. 相似文献
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《Chronobiology international》2013,30(5):809-822
We studied the influence of genetic factors on individual differences in morningness-eveningness in a sample of Dutch twin families. Data were collected from adolescent twins (mean age 17.8 yr) and their parents (mean age of fathers 48.0 yr and of mothers 46.0 yr) and a sample of older twins (mean age 46.5 yr). Scores on morningness-eveningness were rated on a 5-point scale. Parents were more morning oriented than their children, and women were more morning oriented than men. With a twin-family study, separation of genetic and environmental influences on variation in morningness-eveningness is possible. Including parents and older twins in the study makes it possible to explore generation differences in these effects. The correlation between monozygotic twins was more than twice the correlation between dizygotic twins. This indicates that genetic effects may not operate in an additive manner. Therefore, a model that included genetic dominance was explored. Biometrical model fitting showed no sex differences for the magnitude of genetic and environmental factors. The total heritability—the sum of additive and nonadditive genetic influences—for morningness-eveningness was 44% for the younger generation and 47% for the older generation. However, the genetic correlation between the generations turned out to be lower than 0.5, suggesting that different genes for morningness-eveningness are expressed in both generations. (Chronobiology International, 18(5), 809–822, 2001) 相似文献
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P. S. Soltis 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1986,73(1):88-93
Summary Interspecific heritability values were estimated using parent-offspring regression analyses for 11 morphological traits differentiating Clarkia nitens and C. speciosa subsp. polyantha. Estimates ranged from near 0 for anther color and germination percentage, to 0.8 for calyx length and petal tip color. Phenotypic, genetic, and environmental correlation matrices were computed to determine the extent of interspecific correlations of traits. Cluster analyses of the genetic and environmental correlation matrices each resulted in three clusters of correlated traits; however, the clusters derived from the two matrices were different. The clusters produced by analysis of the environmental correlation matrix were similar to the factors obtained from principal component analysis of the phenotypic correlation matrix. Genetic correlations may result from strong linkage due to interspecific chromosomal differences. 相似文献
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Summary Previous work has demonstrated the value of dynamic programming models for the analysis of parental decision making. In the present paper we extend this approach to analyse conflicts between parents and their offspring, and develop a dynamic ESS model of feeding and fledging of nestling birds. In order to simplify the formulation and solution of the dynamic ESS model, we adopt an assumption of alternating decisions: in each time period the parent first decides whether to continue provisioning the nestling, after which the nestling decides whether to leave the nest. The model takes into account numerous tradeoffs involved in parent-offspring decisions, including differential growth and mortality rates for offspring in and out of the nest, risk of fledging, relation between long-term survival and post-breeding mass of offspring, and parental mortality risk associated with provisioning of offspring. Depending on assumed parameter values, the model is capable of predicting a wide range of feeding-fledging behaviour. The model is applied specifically to the juvenile life history of dovekies (Alle alle), and provides a behavioural explanation for the phenomenon of pre-fledging mass recession in this species. 相似文献
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In birds, parents may provide differential food provisioning among offspring according to their sex. Here, we test the hypothesis that events linked to the fine dynamics of begging behaviour could modulate parental preferences. After evaluating the preference related to chick sex for each parent of six Zebra Finch Taeniopygia guttata pairs, we studied the possible modifications of this preference when offspring begging was asynchronous. Our observations show that male parents follow a "first come, first served" rule, whereas females keep their initial choice. Although this study remains preliminary due to the sample size, it underlines the potential importance of investigating fine temporal features of begging behaviour to fully understand parents' provisioning strategies. 相似文献