Stratigraphie et chronologie du site de Gaolingpo dans le bassin de Bose,sud de la Chine

The Bose Paleolithic industry in the Bose Basin, Guangxi, South China is well known in the international scientific community for its bearing handaxes dated back to 803 ka. Seven terraces were developed in the basin and terrace 4 is the most important because handaxes and tektites were recovered from this terrace. Since the first site was discovered in 1973, additional sites of the Bose Paleolithic industry have been investigated and excavated, most of which are located on terrace 4. The previous studies concluded that there is only one phase within this industry and its age is 803 ka. However, before 2013, no attempt had been made to dig down to the basal gravels from the top of terrace 4 in archaeological excavations. Therefore, the stratigraphy and the layers from which the stone artifacts derive of terrace 4 are not clear. In 2013–2014, we conducted an excavation of 200 m² at the Gaolingpo site, which is one of the most important Paleolithic sites in the Bose Basin. We excavated to the basal gravel deposits from the top of this terrace, and a section of more than 7 meters thick deposit was exposed and clearly shows the stratigraphic layers of Pleistocene and Holocene deposits. Furthermore, features and about 800 stone artifacts including choppers, picks, scrapers, etc. were excavated from several stratigraphic layers, which are different in age and other aspects. Based on stratigraphy and the stone artifacts, three stages of Paleolithic cultural remains from the Gaolingpo site can be established. The first stage is in the age of at leat 803 ka. The second stage can be dated to 15 ka and the third stage to about 10 ka.     

L’évolution des assemblages lithiques des niveaux du Paléolithique moyen de l’Abrigo de la Quebrada (Valencia,Espagne)

Abrigo de la Quebrada offers an exceptional sequence with nine occupation levels which seven belongs to Middle Paleolithic. The division between levels II to V and VII to IX by a sterile level VI allow us to study diachronic changes on raw materials and knapping systems. This data is compared with other contemporary sites to evaluate technological trends and the raw material availability in the central region of Mediterranean area.     

山西晋中小南庄墓地人骨的C、N稳定同位素:试析小麦在山西的推广

小麦何时何地对中国北方传统的粟黍农业产生影响是近些年学术界研究的焦点问题之一。相关研究表明,小麦对中国北方不同地区粟黍农业的影响存在时间上的差异。古文献及考古研究表明,小麦在龙山时期就开始在中国北方地区出现,但直到东周及其后才逐步对粟黍农业产生显著的影响。为了探索小麦在东周时期在山西地区推广的程度和其对先民食物结构和生业经济的影响程度及其背后的内在动因等,本文选取晋中小南庄墓地东周时期人骨进行了C、N稳定同位素分析,结果显示先民的δ~(13)C值和δ~(15)N值都比较集中(δ~(13)C值的范围为-9.0‰～-7.5‰,均值为-8.0‰±0.4‰,n=16;δ~(15)N值的范围为9.0‰-11.7‰,均值为10.5‰±0.9‰;n=16),说明他们以C_4类食物为主,也有少量C_3类食物,但动物蛋白消费有所区分。据他们对动物蛋白占有的不同,晋中小南庄墓地东周时期人至少可以划分为两个经济群体,第一个群体可能从事农耕经济,第二群体可能从事畜牧经济。从事农耕经济人群的食物中的C_3食物应该主要来源于小麦,这说明小麦在东周时期开始在晋中地区有所推广。小麦在山西地区的推广、种植和使用,对传统的粟黍农业产生了相应的影响,使得先民种植农作物的种类有所增加,这应该加快了秦汉时期农业高峰期的形成。然而,山西地区小麦的推广相对缓慢,这可能与当地根深蒂固的粟黍经济和饮食习惯密切相关。     

河北阳原小长梁遗址哺乳类化石及其时代

小长梁遗址中的旧石器以小型石器为主,打制技术相当进步,其类型与欧洲某些更晚期的旧石器有某些相似之处,而与旧石器伴生的哺乳动物化石则是泥河湾早更新世的重要成员,古地磁初步测试结果接近167万年。     

猿人洞的溶洞演化和堆积旋回与北京猿人生活环境

猿人洞的溶洞演化过程按岩溶洞穴发生发展规律可划分为６个阶段．在洞穴发育的填充过程中,依据堆积物的成因类型,猿人洞中的中更新世洞穴堆积层可分为７个堆积旋回．每个堆积旋回可与年代相当的黄土堆积旋回和深海气候旋回—一对应．堆积旋回所显示的气候和洞穴环境变化均与北京猿人生活环境及其旧石器文化的发展有着密切的关系．     

Expression of glycoprotein-processing enzymes in Escherichia coli as fusion proteins

A truncated Man9-mannosidase gene and a full-length -1,4-galactosyltransferase gene were isolated from human kidney and placenta cDNAs, respectively. Both genes were cloned in plasmid pMAL-c2 to produce fusions with maltose-binding protein. Fusion products were purified by affinity chromatography. Purified enzymes were assayed using pyridyl-amino labelled oligosaccharides as substrates and analysed by HPLC.     

Habitat-dependent thermal regimes of two hawaiian geckos (Reptilla: gekkonidae)

1. 1.Effects of habitat on the thermal regime were investigated in two diurno—nocturnal geckos in Hawaii.

2. 2.In trees Hemidactylus frenatus thermoregulated in daytime with body temperature (BT) above air temperture (AT); in houses some thermoregulated likewise in daytime but mainly the species thermoregulated at night, on electric lamps, to the same BT as in trees by day.

3. 3.Lepidodactylus lugubris in trees thermoregulated in daytime, its BT lower than in H. frenatus. In the rocks it had at night a BT resembling that in trees in daytime, because the thermal cycle in rock crevices lagged behind outside AT.

4. 4.The flexibility of these geckos in thermal regime and activity cycle preadapts them to both migration and invasion of houses.

白岩脚洞石器类型的研究

本文讨论和分析了贵州普定白岩脚洞发现的砾石石器(砍砸器)和石片石器的类型。刮削器数量多,类型复杂,加工精致;尖状器数量较少,加工也不很精致;端刮器和修背石刀不太发达;雕刻器和凹缺刮器并不发达;砍砸器仍占相当比例。     

Selective updates on mechanisms of action of positive inotropic agents

Several extensive reviews concerning the actions of new positive inotropic agents in the treatment of congestive heart failure, often with reference to their mechanism of action, have recently been published [1–7]. Each of them has presented specific points of view. This review will place special emphasis on the significance of intracellular sodium activity for the modulation of myocardial inotropy; the continuing importance, after a 200 year history, of the use of cardiac glycosides as strong inotropic agents; the emerging significance of the phosphoinositide (PIP₂) pathway to provide additional second messengers for the modulation and regulation of cardiac inotropy; the contribution of the ₁-adrenergic system to cardiac inotropy; the increasing awareness of the significant involvement of adenosine and its antagonists in cardiac function; and the increasing realization that myocardial tissues are not homogeneous, i.e., that in many species the atrial and ventricular tissues are using different, even opposite mechanisms in the generation of their functional responses.     

Characterization of binding and receptors for epidermal growth factor in smooth muscle

Summary The mitogenic and differentiation-inducing activities of epidermal growth factor (EGF) in epithelial tissues have been well described. Since non-mitogenic effects of EGF, especially in mesenchymal tissues such as smooth muscle are not well-known (Nanney et al. 1984), we have examined EGF-binding and receptors in smooth muscle from many sites. Specific EGF binding sites were detected by incubating small pieces of tissue with ¹²⁵I-EGF; immunoreactive EGF receptors were detected by immunohistochemistry. In-situ localization of ¹²⁵I-EGF binding sites and immunoreactive EGF receptors of smooth muscle cells in intact mammalian tissues were identical using either ¹²⁵I-EGF autoradiography or anti-EGF receptor antibody in an immunoperoxidase method. Cultured rat aortic smooth muscle also contained specific EGF receptors as detected by their biological response to EGF-binding and internalization of ¹²⁵I-EGF, as well as EGF-stimulated phosphorylation of a 170K protein. The presence of EGF receptors in a well-differentiated smooth muscle cell indicates that EGF may play a physiological, but non-mitogenic role in mammalian tissues in vivo.