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Marie-Isabel Aguilar Gary D. Fallon Penelpe A. Mayes Sofia Nordin Andrea J. Robinson Mark L. Rose Filisaty Vounatsos Bradley Wilman Patrick Perlmutter 《International journal of peptide research and therapeutics》2003,10(5-6):597-604
Two approaches, based on imino-aldol additions, to the asymmetric synthesis of cyclic β-amino acids are reported. In each case a chiral auxiliary was employed attached either to the enolate or to the imine. The
relative efficacy of these two synthetic methods is also briefly compared with the former still the preferred route as the
latter is currently limited to the preparation of N-sulfonyl β-amino acids. 相似文献