全文获取类型
收费全文 | 6128篇 |
免费 | 455篇 |
国内免费 | 1882篇 |
出版年
2024年 | 52篇 |
2023年 | 130篇 |
2022年 | 218篇 |
2021年 | 278篇 |
2020年 | 228篇 |
2019年 | 249篇 |
2018年 | 282篇 |
2017年 | 205篇 |
2016年 | 258篇 |
2015年 | 225篇 |
2014年 | 348篇 |
2013年 | 445篇 |
2012年 | 271篇 |
2011年 | 361篇 |
2010年 | 308篇 |
2009年 | 356篇 |
2008年 | 415篇 |
2007年 | 365篇 |
2006年 | 375篇 |
2005年 | 366篇 |
2004年 | 328篇 |
2003年 | 289篇 |
2002年 | 207篇 |
2001年 | 166篇 |
2000年 | 179篇 |
1999年 | 148篇 |
1998年 | 138篇 |
1997年 | 120篇 |
1996年 | 123篇 |
1995年 | 109篇 |
1994年 | 102篇 |
1993年 | 88篇 |
1992年 | 105篇 |
1991年 | 100篇 |
1990年 | 63篇 |
1989年 | 59篇 |
1988年 | 55篇 |
1987年 | 45篇 |
1986年 | 59篇 |
1985年 | 37篇 |
1984年 | 31篇 |
1983年 | 22篇 |
1982年 | 34篇 |
1981年 | 27篇 |
1980年 | 24篇 |
1979年 | 9篇 |
1978年 | 18篇 |
1977年 | 10篇 |
1976年 | 11篇 |
1972年 | 6篇 |
排序方式: 共有8465条查询结果,搜索用时 15 毫秒
131.
Paula Cabral Eterovick José Eugênio Crtes Figueira JoaTo Vasconcellos-Neto 《Biological journal of the Linnean Society. Linnean Society of London》1997,61(4):485-499
Cryptic coloration is found in many Orthoptera, especially in Acrididae, showing a great variety of forms. In a grasshopper assemblage in southeastern Brazil, preferences for escape places were detected; grasshoppers tended to escape to backgrounds in which they seem to be more cryptic. Coloration was measured using the Simpson diversity index, to quantify 'aspect diversity' (diversity of colours and shapes of patches along the insect's body). A weak positive correlation was found between grasshoppers' aspect diversity and diversification in use of escape places (use of many backgrounds to escape). Grasshoppers with similar colour patterns tended to use the same structures (leaves, sandy soil, stones) to escape. 相似文献
132.
抗白粉病小麦染色体组型的分子标记与生化标记分析 总被引:1,自引:0,他引:1
应用与小麦第六同源群有关的分子和生化标记,包括DNA探针pSc5·3H3和pSR167以及同工酶Est-5和a-Amy-1,对来自六倍体小黑麦Beagle与普通小麦科冬58杂交后代F1花粉植株的抗白粉病株系M24.M09及M17进行了分析。结果表明,M24、M09及M17不同程度地含有黑麦染色体成分,而且电泳谱带差别较大,据此推断,M09为6RL的易位系。因此,生化和分子标记不仅可以用于确定外源片段的存在,而且可以帮助确定染色体组型和外源片段的位置 相似文献
133.
采用辣根过氧化物酶顺、逆行标记方法对鸣禽鸟蜡嘴雀控制发声的神经核团、脑干听觉核团及神经通路,从外周至中枢逐级进行了追踪研究。结果表明:1.控制发声的神经核团及通路,前脑古纹状体腹内侧粗核是大脑控制发声的重要核团之一,它发出枕中脑后束经端脑前联合呈双侧支配延脑中间核,中间核又发出舌下神经经气管鸣管分支支配鸣肌,中间核同时也接受中脑背内侧核的支配,2.脑干听觉中枢及通路,中脑背外侧核是脑干较高级听觉中枢、初级中枢耳蜗核由角核和前庭外侧核组成,NA发出以对侧为主的纤维经外侧丘系可直接传入中脑背外侧核形成脑干听觉直接通路。 相似文献
134.
The effects of different seed sizes, planting densities and planting patterns on the transmission of silver scurf (Helminthosporium solani) and black scurf (Rhizoctonia solani) diseases of potatoes were examined in five field experiments with cv. Estima in 1991–93.
In all experiments, silver scurf was more severe with increase in seed size and planting density. At high planting density, silver scurf was less severe from a square planting pattern than from planting in wide rows. The incidence of black scurf also tended to increase with increase in seed size and was increased markedly high planting density. 相似文献
In all experiments, silver scurf was more severe with increase in seed size and planting density. At high planting density, silver scurf was less severe from a square planting pattern than from planting in wide rows. The incidence of black scurf also tended to increase with increase in seed size and was increased markedly high planting density. 相似文献
135.
L. Kolton J. M. Camhi 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1995,176(5):691-702
The cockroachPeriplaneta americana responds to wind puffs by turning away, both on the ground and when flying. While on the ground, the ventral giant interneurons (ventrals) encode the wind direction and specify turn direction, whereas while flying the dorsal giant interneurons (dorsals) appear to do so. We report here on responses of these cells to controlled wind stimuli of different directions. Using improved methods of wind stimulation and of positioning the animal revealed important principles of organization not previously observed.All six cells of largest axonal diameter on each side respond preferentially to ipsilateral winds. One of these cells, previously thought to respond non-directionally (giant interneuron 2), was found to have a restricted directional response (Fig. 3). The organization of directional coding among the ventral giant interneurons is nearly identical to that among the dorsals (Fig. 2). Each group contains, on each side, one cell that responds primarily to wind from the ipsilateral front, another primarily in the ipsilateral rear, and a third responding more broadly to ipsilateral front and rear.These results are discussed in terms of the mechanisms of directional localization by the assembly of giant interneurons.Abbreviations
GI
giant interneuron
-
vGI
ventral giant interneuron
-
dGI
dorsal giant interneuron
-
CF
5-carboxyfluorescein
-
A6
6th abdominal ganglion
- TI
thoracic interneuron
-
BED
best excitatory direction 相似文献
136.
B. A. O'Gara W. O. Friesen 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1995,177(5):627-636
Cell Tr2 is a neuron in the subesophageal ganglion of the leech that can trigger swim episodes. In this report, we describe the ability of Tr2 to terminate ongoing swim episodes as well as to trigger swimming. Stimulation of Tr2 terminated ongoing swim episodes in nearly every preparation tested, while Tr2 stimulation triggered swim episodes in only a minority of the preparations. We suggest that the primary role of Tr2 is in the termination rather than the initiation of swimming activity.The swim trigger neuron Tr3 and a swim-gating neuron, cell 21, hyperpolarized during Tr2-induced swim termination. Another swim-gating neuron, cell 204 was sometimes slightly excited, but more often, hyperpolarized during Tr2-induced swim termination. In contrast to these cells, Tr2 stimulation excited another swim-gating neuron, cell 61. The responses of the swimgating cells were variable in amplitude and sometimes not evident during Tr2-induced swim termination. Hence, the effects of Tr2 stimulation on swim-gating neurons seem unlikely to be the direct cause of swim termination.Oscillator cells examined during Tr2-induced swim termination include: 27, 28, 33, 60, 115, and 208. The largest effect seen in an oscillator neuron was in cell 208, which was repolarized by up to 10 mV during Tr2 stimulation. Tr2 stimulation did not produce any obvious synaptic effects in motor neurons DI-1, VI-1, and DE-3. Our findings indicate that other, yet undiscovered, connections are likely to be important in Tr2-induced swim termination. Therefore, we propose that cell Tr2 is probably a member of a distributed neural network involved in swim termination.Abbreviations
DP
dorsal posterior nerve
-
Mx
midbody ganglion x
-
Rx
neuromere x of the subsesophageal (rostral) ganglion
-
DE
dorsal excitatory motor neuron
-
DI
dorsal inhibitory motor neuron
-
VI
ventral inhibitory motor neuron 相似文献
137.
Modeling the leech heartbeat elemental oscillator I. Interactions of intrinsic and synaptic currents
Farzan Nadim Øystein H. Olsen Erik de Schutter Ronald L. Calabrese 《Journal of computational neuroscience》1995,2(3):215-235
We have developed a biophysical model of a pair of reciprocally inhibitory interneurons comprising an elemental heartbeat oscillator of the leech. We incorporate various intrinsic and synaptic ionic currents based on voltage-clamp data. Synaptic transmission between the interneurons consists of both a graded and a spike-mediated component. By using maximal conductances as parameters, we have constructed a canonical model whose activity appears close to the real neurons. Oscillations in the model arise from interactions between synaptic and intrinsic currents. The inhibitory synaptic currents hyperpolarize the cell, resulting in activation of a hyperpolarization-activated inward currentI
h
and the removal of inactivation from regenerative inward currents. These inward currents depolarize the cell to produce spiking and inhibit the opposite cell. Spike-mediated IPSPs in the inhibited neuron cause inactivation of low-threshold Ca++ currents that are responsible for generating the graded synaptic inhibition in the opposite cell. Thus, although the model cells can potentially generate large graded IPSPs, synaptic inhibition during canonical oscillations is dominated by the spike-mediated component. 相似文献
138.
Dr. P. K. Khosla O. P. Toky R. P. Bisht S. Hamidullah 《Trees - Structure and Function》1995,10(2):108-113
In the mid-western Himalaya (altitude 1350 m, rainfall 1100 mm), multipurpose trees found as escapees in agricultural fields or naturally growing in the forests, play an important role in providing fuel, fooder and small timber to the farmers. Shoot elogation, and tree architecture of 4 year old trees of Grewia optiva, Robinia pseudoacacia and Celtis australis (early successionals), and Quercus leucotrichophora, Q. glauca and Ilex odorata (late successionals), were analyzed. All the late successional species showed a proleptic type of bud and branch production, while the early successional trees made growth through syllepsis. The shoot elongation differed significantly (P <0.05) with the crown position, and ranged from 11 to 30 cm in different species. Early successional species tended to maintain a comparatively narrow crown and showed a significantly (P <0.05) higher ramification ratio, and multilayered canopy. The late successionals, in contrast, showed a wide crown with monolayered canopy, adapted to the weak light intensity. There was only one flush of leaves in Q. leucotrichophora and Q. glauca while in the rest of the species there were two distinct flush periods. The results are important for the management of agroforestry trees. 相似文献
139.
Astrid Zimmermann Anke Haina Ute Gröschel-Stewart 《Development genes and evolution》1995,204(4):271-275
The development of the autonomic ganglia of Auerbach's plexus and gizzard smooth muscle was studied in chicken embryos. Nervous system and smooth-muscle-specific antibodies were employed in immunofluorescence stainings on tissue sections to investigate the temporal and spatial frame of neural and muscular differentiation in relation to each other. Subserosal clusters of neural cells were clearly demonstrable at embryonic day 5 (ED5), the earliest stage analysed, with the monoclonal antibody El (SGIII-1). Fine nerve fibres (ED6) and, later, large axon bundles projecting from subserosal neuron clusters towards the lumen were followed and found to reach the luminal border by ED11. Already in early development the area of the future laminar tendons on the ventral and dorsal surface of the gizzard was devoid of neuroblasts, and nerve fibres were not extending to the muscle-tendon borderline until ED16. Double stainings with antibodies to smooth muscle myosin (SMM) and El revealed that SMM expression, taken as an indicator for muscle differentiation, followed neural growth. It was first detectable in close apposition to the differentiating neuroblasts in the caudal and cranial portion of the gizzard at ED6. With further development, myosin expression proceeded inward towards the lumen in a wave which followed the ingrowth of E1-positive nerve fibres from the prospective Auerbach plexus. Neuromuscular differentiation deviated from this pattern in the lateral tendon area where nerve growth was delayed and myosin expression preceeded the arrival of E1-positive nerve fibres. The findings suggest that the gizzard could serve as a model system for the analysis of potential early nervous system imprints on smooth premuscle mesenchyme differentiation. 相似文献
140.
Frank D. Snnichsen Brian D. Sykes Peter L. Davies 《Protein science : a publication of the Protein Society》1995,4(3):460-471
Type II antifreeze proteins (AFP), which inhibit the growth of seed ice crystals in the blood of certain fishes (sea raven, herring, and smelt), are the largest known fish AFPs and the only class for which detailed structural information is not yet available. However, a sequence homology has been recognized between these proteins and the carbohydrate recognition domain of C-type lectins. The structure of this domain from rat mannose-binding protein (MBP-A) has been solved by X-ray crystallography (Weis WI, Drickamer K, Hendrickson WA, 1992, Nature 360:127-134) and provided the coordinates for constructing the three-dimensional model of the 129-amino acid Type II AFP from sea raven, to which it shows 19% sequence identity. Multiple sequence alignments between Type II AFPs, pancreatic stone protein, MBP-A, and as many as 50 carbohydrate-recognition domain sequences from various lectins were performed to determine reliably aligned sequence regions. Successive molecular dynamics and energy minimization calculations were used to relax bond lengths and angles and to identify flexible regions. The derived structure contains two alpha-helices, two beta-sheets, and a high proportion of amino acids in loops and turns. The model is in good agreement with preliminary NMR spectroscopic analyses. It explains the observed differences in calcium binding between sea raven Type II AFP and MBP-A. Furthermore, the model proposes the formation of five disulfide bridges between Cys 7 and Cys 18, Cys 35 and Cys 125, Cys 69 and Cys 100, Cys 89 and Cys 111, and Cys 101 and Cys 117.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献