全文获取类型
收费全文 | 3841篇 |
免费 | 91篇 |
国内免费 | 173篇 |
专业分类
4105篇 |
出版年
2023年 | 20篇 |
2022年 | 39篇 |
2021年 | 26篇 |
2020年 | 30篇 |
2019年 | 52篇 |
2018年 | 66篇 |
2017年 | 53篇 |
2016年 | 40篇 |
2015年 | 83篇 |
2014年 | 144篇 |
2013年 | 156篇 |
2012年 | 136篇 |
2011年 | 151篇 |
2010年 | 166篇 |
2009年 | 258篇 |
2008年 | 219篇 |
2007年 | 240篇 |
2006年 | 192篇 |
2005年 | 176篇 |
2004年 | 157篇 |
2003年 | 135篇 |
2002年 | 73篇 |
2001年 | 71篇 |
2000年 | 82篇 |
1999年 | 105篇 |
1998年 | 111篇 |
1997年 | 92篇 |
1996年 | 76篇 |
1995年 | 78篇 |
1994年 | 82篇 |
1993年 | 71篇 |
1992年 | 70篇 |
1991年 | 66篇 |
1990年 | 66篇 |
1989年 | 67篇 |
1988年 | 52篇 |
1987年 | 53篇 |
1986年 | 35篇 |
1985年 | 42篇 |
1984年 | 39篇 |
1983年 | 17篇 |
1982年 | 32篇 |
1981年 | 23篇 |
1980年 | 26篇 |
1979年 | 20篇 |
1978年 | 17篇 |
1977年 | 24篇 |
1976年 | 32篇 |
1973年 | 10篇 |
1972年 | 13篇 |
排序方式: 共有4105条查询结果,搜索用时 0 毫秒
91.
Prof. Sven O. E. Ebbesson 《Cell and tissue research》1980,213(2):179-212
Summary Recently discovered neocortical equivalents in anamniotes and certain patterns of interspecific variability in brain organization provide new insights into evolutionary and ontogenetic mechanisms of development. The new data suggest that nervous systems become more complex, not by one system invading another, but by a process of parcellation that involves the selective loss of connections of the newly formed daughter aggregates and subsystems. The parcellation process is reflected in the normal ontogenetic development of the CNS in a given species and can be manipulated, to a certain extent, by deprivation or surgically induced sprouting.The parcellation theory allows certain predictions about the range of variation of a given system at all levels of analysis including the cellular and aggregate levels. For example, the interspecific variability in organization of cortical columns, thalamic nuclei, cortical areas and tectal layers can be explained. The findings, summarized here, suggest that diffuse, undifferentiated systems existed in the beginning of vertebrate evolution and that during the evolution of complex behaviors, and analytical capacities related to these behaviors, a range of patterns of neural systems evolved that relate to these functions. One principle underlying the growth, differentiation and multiplication of neural systems appears to be the process of parcellation as defined by the theory.Presented in part at the meeting of the British Society for Experimental Biology, Belfast, Ireland, July 1979 相似文献
92.
Richard Holmquist 《Journal of molecular evolution》1980,15(2):149-159
Summary It is shown how REH theory in conjunction with mRNA or gene sequence data can be used to obtain estimates of the fixation intensity, the number of varions, and the total mutations fixed between homologous pairs of nucleic acids. These estimates are more accurate than those that can be derived from amino acid sequence data. The method is illustrated for and hemoglobin genes and these improved estimates are compared with those made from the amino acid sequences for which those genes code. Significant differences are found between the estimates made by these two methods. For the hemoglobin gene sequences examined here, the fixation intensity is some-what less than the protein data had suggested, and the number of rations is considerably greater. Depending on the gene sequences examined, between 62 and 83% of the codons appear able to fix mutations during the divergences considered. This reflects the constraints of natural selection on acceptable mutations. The total number of base replacements separating the genes for human, mouse, and rabbit hemoglobin varies from 61 to 105 depending on the pair examined. Rabbit and hemoglobin are separated by at least 290 fixed mutations. For such distantly related sequences estimates made from protein and mRNA data differ less, reflecting the higher quality of information from the many observed changes in primary structure. The effects of nonrandom gene structure on these evolutionary estimates and the fact that various genetic events are not equiprobable are discussed. 相似文献
93.
长阳青铜时代与大同北魏朝代人类牙齿的形态变异 总被引:2,自引:4,他引:2
本文记述了湖北长阳县深潭湾青铜时代和山西大同市郊北魏朝代两处墓葬遗址出土的人类牙齿形态变异的状况,提供人们对牙齿形态种种变异的认识,探索非测量性牙齿特征在研究种族和人群之间关系中的意义。 相似文献
94.
Recent localization of cohesin association regions along the yeast chromatin fibre suggests that compositional variability of DNA in yeast is related to the function and organization of the chromosomal loops. The bases of the loops, where the chromatin fibre is attached to the chromosomal axis, are AT-rich, bind cohesin, and are flanked by genes transcribed convergently. The hotspots of meiotic recombination are mainly found in the GC-rich parts of the loops, ‘external’ with respect to the chromosomal axis, frequently in the vicinity of the promoters of divergently transcribed genes. There are two possible reasons why the regions of the hotspots of recombination were enriched in GC content during evolution. One is a biased repair of recombination intermediates, and the second is a selective advantage due to an increased chromatin accessibility, which may have the carriers of GC-enriched alleles over the carriers of AT-rich alleles. 相似文献
95.
The number of serotonin-expressing neurons in the nervous system of Euarthropoda is small and their neurites have a characteristic branching pattern. They can be identified individually, which provides a character well suited for phylogenetic analyses. In order to gain data that may be useful in the ongoing discussion on insect–crustacean relationships, we documented the pattern of serotonin immunoreactive neurons in the ventral nerve cord of four crustacean species: the phyllocarid malacostracan Nebalia bipes Fabricius, 1780 (Phyllocarida, Leptostraca) and the entomostracans Artemia salina Linnaeus, 1758 (Branchiopoda, Anostraca, Sarsostraca), Triops cancriformis Bosc, 1801 (Branchiopoda, Phyllopoda, Calmanostraca, Notostraca), and Leptestheria dahalacensis Rüppell, 1837 (Branchiopoda, Phyllopoda, Diplostraca, Conchostraca, Spinicaudata). In the entomostracan taxa investigated, the pattern of serotonergic cells in the thoracic hemiganglia comprises an anterior and a posterior bilateral pair of neurons with ipsi- and/or contralateral neurites. Comparing these data to existing information on serotonin-immunoreactivity in the ventral nerve cord of other malacostracan and entomostracan groups enabled us to determine several features of these thoracic neurons being part of the ground pattern of these taxa. Our data demonstrate that studying individually identifiable neurons in Arthropoda can be used to analyse the phylogeny of this taxon. 相似文献
96.
97.
A genetic map of potato (Solanum tuberosum) integrating molecular markers,including transposons,and classical markers 总被引:2,自引:0,他引:2
J. M. E. Jacobs H. J. Van Eck P. Arens B. Verkerk-Bakker B. te Lintel Hekkert H. J. M. Bastiaanssen A. El-Kharbotly A. Pereira E. Jacobsen W. J. Stiekema 《TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik》1995,91(2):289-300
A genetic map of potato (Solanum tuberosum L.) integrating molecular markers with morphological and isozyme markers was constructed using a backcross population of 67 diploid potato plants. A general method for map construction is described that differs from previous methods employed in potato and other outbreeding plants. First, separate maps for the female and male parents were constructed. The female map contained 132 markers, whereas the male map contained 138 markers. Second, on the basis of the markers in common the two integrated parental maps were combined into one with the computer programme JoinMap. This combined map consisted of 175 molecular markers, 10 morphological markers and 8 isozyme markers. Ninety-two of the molecular markers were derived from DNA sequences flanking either T-DNA inserts in potato or reintegrated maize transposable elements originating from these T-DNA constructs. Clusters of distorted segregation were found on chromosomes 1,2,8 and 11 for the male parent and chromosome 5 for both parents. The total length of the combined map is 1120 cM. 相似文献
98.
珍珠菜属四种植物的核型分析 总被引:2,自引:0,他引:2
对珍珠菜属4种植物的核型进行了研究。结果表明,叶头过路黄(Lysimachia phyllocephala Hand.-Mazz.)的核型为:2n=2x=24=2m 6sm 2st 14t,茂汶过路黄(L. stellarioidesHand.-Mazz.)的核型为:2n=2x=24=4m 2sm 18t,均属首次报道。矮桃(L. clethroidesDuby)的核型为:2n=2x=24=16m 8sm(1SAT),腺药珍珠菜(L. stenosepala Hemsl.)的核型为:2n=2x=24=10m 12sm 2st,与前人报道的有所不同。还对该属已报道的23种植物的核型进行了比较。 相似文献
99.
The interaction between mobile DNA sequences and their hosts raises important questions in the context of hosts which reproduce clonally with only rare horizontal transmission between clones. The activity of some mobile DNAs as reversible mutators of genes raises the possibility that, in a fluctuating environment, cells may gain an advantage if they have mobile DNAs which mutate genes whose inactivation is favoured in one of the environments that the population encounters. Here we analyse a model of this process and ask what would be the optimal rate of transposition in a population whose elements are maintained by this mechanism. We also examine the impact of horizontal transfer on such a population. With movement of elements between cells, we can imagine elements with differing rates of transposition and host cells with differing rates of transposition. We find that evolution in the population of elements favours a rapid rate of transposition, and evolution of the host cells favours cells in which this rapid rate of element-dependent transposition results in an optimal rate of transposition per cell. However, when horizontal transfer rates are high, some unexpected features of the model are observed. In particular, a polymorphism between cell types (some with an optimal rate of transposition and some with no transposition at all from endogenous elements) can be stably maintained. We consider the possible biological predictions of this analysis. 相似文献
100.