Correlations of IL-23R gene polymorphism with clinicopathological characteristics and prognosis of hepatocellular carcinoma patients after interventional therapy

In this study, we summarized the association of IL-23R gene polymorphisms with hepatocellular carcinoma (HCC). A total of 270 HCC patients were selected as HCC group, and 251 healthy individuals served as the control group. PCR-RFLP was performed to detect IL-23R gene polymorphism, including rs17375018 and rs11805303. Survival rate and risk factors of HCC were identified. The findings suggested that IL-23R rs17375018 was correlated with genetic susceptibility to HCC, and GC haplotype was closely linked with the risk factors of HCC. Moreover, rs17375018 polymorphism was related to portal vein tumor thrombus (PVTT) and alcohol consumption in HCC patients, while prognosis was better in HCC patients with AA genotype of rs17375018 polymorphism. Lastly, GG genotype in rs17375018, PVTT and TNM stage III and IV were identified as independent risk factors for HCC. In conclusion, IL-23R rs17375018 polymorphism might serve as a prognostic factor in patients with HCC after interventional therapy.     

High prevalence of liver and intestinal fluke infections among residents of Savannakhet Province in Laos

The prevalence of liver and intestinal fluke infections was surveyed on residents of Savannakhet Province, Laos. Fecal specimens were collected from a total of 981 residents in 4 Mekong riverside villages and examined by the Kato-Katz thick smear technique. The results revealed that the overall helminth egg positive rate was 84.2%, and the positive rate for small trematode eggs, including Opisthorchis viverrini, heterophyids, or lecithodendriids, was 67.1%. To obtain adult flukes, 38 small trematode egg positive cases were treated with a 20-30 mg/kg single dose of praziquantel and purged. Diarrheic stools were then collected from 29 people and searched for helminth parasites using stereomicroscopes. Mixed infections with O. viverrini and 6 kinds of intestinal flukes were found, namely, Haplorchis taichui, Haplorchis pumilio, Haplorchis yokogawai, Prosthodendrium molenkampi, Phaneropsolus bonnei, and echinostomes. The total number of flukes collected was 7,693 specimens (av. no. per treated person; 265.3). The most common species was O. viverrini, followed by H. taichui, P. molenkampi, echinostomes, H. pumilio, P. bonnei, and H. yokogawai. The results indicate that foodborne liver and intestinal fluke infections are prevalent among residents of Savannakhet Province, Laos.     

云南省气候生产潜力的时空变化

利用云南省1961-2017年101个国家级气象站年平均气温、年降水量资料,运用Miami模型、Thornthwaite Memorial模型计算了云南省3种气候生产潜力,用Mann-Kendell法进行突变检验,并分析了时空分布特征及未来趋势.结果表明:研究期间,云南平均温度气候生产潜力(Yt)、降水气候生产潜力(Yr)和蒸散气候生产潜力(Ye)值分别为1968、1477、1434 g·m^-2·a^-1,Yt呈波动上升状态,Yr/Yt值显示地区间水热配比差异大,约束性条件也明显不同;气候生产潜力存在突变现象,Yt在2001年开始明显突变,Yr没有突变,Ye在2002-2004年有突变;气候生产潜力及气候倾向性空间分布不均,全省各地年平均Yt、Yr和Ye分别在1030~2465、927~2341和832~1995 g·m^-2·a^-1,3种气候生产潜力均为滇西北和滇东北最低,滇西南和滇南最高,大部分地区Yt、Yr和Ye的气候倾向率分别为增长、减小和增长趋势;8种模拟未来气候变化的方案(仅气温增加1℃、仅降水增加10%、仅气温降低1℃、仅降水减少10%、气温增加1℃且降水减少10%、气温增加1℃且降水增加10%、气温降低1℃且降水增加10%、气温降低1℃且降水减少10%)将导致研究区Ye分别变化6~45、13~77.2、15~67、-87^-17、-74~46、58~96、-54~57、-101^-59 g·m^-2·a^-1.整体上,如果未来气候趋于"暖湿"化,将有利于研究区农作物增产,如果趋于"冷干"化,将不利于农作物生产.     

山东省植被NPP时空分布特征及驱动因素分析

为了解区域生态系统植被生产力的分布规律及其变化对区域生态调控的作用,该研究基于MOD17A3的年NPP数据,采用一元线性回归分析法和Pearson相关系数法等,分析了2000—2014年山东省植被NPP的时空格局变化特征及其气候、人为等因素对其的影响。结果表明:(1) 2000—2014年,山东省植被NPP总体呈上升趋势,年均值为442 gC·m^-2·a^-1,年总量平均值为63.16 TgC。山东省植被NPP空间分布具有明显的分异特征,其中年均NPP 300～400 gC·m^-2·a^-1的面积最大,占总面积的52.28%,分布于山东省西部的绝大部分区域。(2)山东省植被NPP年增加速率平均值为3.29 gC·m-2·a^-1,增加区域占山东省植被总面积的92.63%。其中,极显著增加区域占山东省总面积的16.56%,主要分布在烟台市、青岛市、日照市、临沂市、潍坊市、东营市和滨州市;显著减少和极显著减少的区域占山东省总面积的1.33%,零星分布在山东省东南部和北部黄河三角洲地区。(3)植被NPP受气候变化和人类活动等因素的共同影响,气候因素中降雨的影响最大,城市化随着人类活动的频繁逐渐成为植被NPP变化的重要驱动力。     

黑龙江青冈地区晚更新世猛犸象-披毛犀动物群生存的环境背景

更新世晚期大型哺乳动物消亡一直是科学界关注的热点科学问题,其消亡的环境背景和影响机制仍没有形成一致观点。我国东北地区晚更新世地层中保存有丰富的猛犸象-披毛犀动物群(Mammuthus-Coelodonta Fauna)化石记录,是研究更新世晚期大型哺乳动物生存环境及消亡过程的理想区域。黑龙江省青冈地区出土有典型的晚更新世哺乳动物化石种类,如真猛犸象(Mammuthus primigenius)、披毛犀(Coelodonta antiquitatis)等。本文以青冈县英贤村化石出土剖面为研究对象,通过孢粉分析,重建猛犸象-披毛犀动物群的生存环境背景。青冈地区猛犸象-披毛犀动物群出土于湖沼相沉积中,研究发现其生存环境的主要植被成分是蒿属、菊科、禾本科、莎草科和云杉属,指示草甸草原为主,局地生长有针叶林的植被景观。欧亚大陆晚更新世高纬度地区广泛分布的猛犸象草原植被曾延伸到我国东北地区。     

穗花杉属——陕西省红豆杉科一新记录属

报道了陕西省红豆杉科一新记录属——穗花杉属(Amentotaxus Pilg.),其新记录种为穗花杉[A.argotaenia(Hance) Pilg.]。文中提供了形态描述和野外照片,凭证标本藏于陕西理工大学植物标本馆。     

湖南省种子植物分布新资料

报道湖南省种子植物新纪录5种(变种),为张氏野海棠Bredia changii、假苞囊瓣芹Pternopetalum tanakaevar.fulcratum、光果悬钩子Rubus glabricarpus、腺毛香简草Keiskea glandulos和江西马先蒿Pediculariskiangsiensis。凭证标本存放于中山大学植物标本馆(SYS)。     

Do Mediterranean‐type ecosystems have a common history?—Insights from the Buckthorn family (Rhamnaceae)

Mediterranean‐type ecosystems (MTEs) are remarkable in their species richness and endemism, but the processes that have led to this diversity remain enigmatic. Here, we hypothesize that continent‐dependent speciation and extinction rates have led to disparity in diversity between the five MTEs of the world: the Cape, California, Mediterranean Basin, Chile, and Western Australia. To test this hypothesis, we built a phylogenetic tree for 280 Rhamnaceae species, estimated divergence times using eight fossil calibrations, and used Bayesian methods and simulations to test for differences in diversification rates. Rhamnaceae lineages in MTEs generally show higher diversification rates than elsewhere, but speciation and extinction dynamics show a pattern of continent‐dependence. We detected high speciation and extinction rates in California and significantly lower extinction rates in the Cape and Western Australia. The independent colonization of four of five MTEs may have occurred conterminously in the Oligocene/Early Miocene, but colonization of the Mediterranean Basin happened later, in the Late Miocene. This suggests that the in situ radiations of these clades were initiated before the onset of winter rainfall in these regions. These results indicate independent evolutionary histories of Rhamnaceae in MTEs, possibly related to the intensity of climate oscillations and the geological history of the regions.     

江西省蚋属一新种(双翅目,蚋科)

首次记述江西省蚋科1新种,庐山蚋Simulium(Simuliun)hushanense sp.nov..新种依其雄性生殖腹板光裸,蛹具6条呼吸丝,似应隶属于蚋亚属的灰额蚋组griseifronsgroup.与报告自马来西亚的显丝蚋S.(S.)grossifilum Takaoka et Davies近似,但后者的雄性尾器与本种迥异,蛹的头毛树状,茧具前侧窗等特征,可资鉴别.