Xanthones from Swertia punctata

Isolation of 1-O-primeverosyl-3,8-dihydroxy-5-methoxyxanthone and 1-O-gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone, along with five known xanthones, isobellidifolin, methylbellidifolin, isoswertianin, methylswertianin and norswertianin-1-O-beta-D-glucoside, from the roots of Swertia punctata is reported. In the aerial parts four xanthones, bellidifolin, methylbellidifolin, swertianolin and mangiferin, and flavone-C-glucoside, isoorientin were identified. The chemotaxonomic and pharmacological significance of these results is discussed.     

Monoamine oxidase inhibitors from Gentiana lutea

Three monoamine oxidase (MAO) inhibitors were isolated from Gentiana lutea. Their structures were elucidated to be 3-3'linked-(2'-hydroxy-4-O-isoprenylchalcone)-(2'-hydroxy-4'-O-isoprenyldihydrochalcone) (1), 2-methoxy-3-(1,1'-dimethylallyl)-6a,10a-dihydrobenzo(1,2-c)chroman-6-one and 5-hydroxyflavanone. These compounds, and the hydrolysis product of 1, displayed competitive inhibitory properties against MAO-B which was more effective than MAO-A.     

A new species of Tachia (Gentianaceae) from Suriname

A new species ofTachia,T. longipes, is described and illustrated. It is distinct from the other species ofTachia not only in its leaf and stem morphology but also in its characteristic pollen. A revised key to the neotropical species ofTachia is also provided. Studies for theFlora of the Guianas. No. 87.     

花锚属一新变型——玉花卵萼花锚

报道了龙胆科卵萼花锚的一个新变型——玉花卵萼花锚。新变型区别于原变型的唯一特征是其花冠为白色,部分花距为黄色。     

Lanostane triterpenes of Canscora decussata

From the aerial parts of Canscora decussata Schult (Gentianaceae), five triterpenes, viz. gluanone, canscoradione, friedelin, fridelan-3-β-ol, and β-amyrin, three sterols, viz. sitosterol, stigmasterol, and campesterol, besides liberal amount of a mixtures of n-alkanes (C₂₇-C₃₁) and n-alkanols (C₂₆-C₃₂) have been isolated. The identity of the compounds has been established by chemical transformations, spectral evidence, and by direct comparison, where possible, with authentic reference materials. Gluanone and canscoradione have not been encountered before in nature.     

Xanthones,flavones and secoiridoids of american Gentiana species

Isoorientin, isoorientin-4′-O-glucoside, gentiopicrin, xanthones with 1,3,5,8 or 1,3,7,8-oxidation pattern have been isolated from five North American Gentiana species (G. affinis, G. algida, G. calycosa, G. detonsa, G. strictiflora) and one South American species (G. cerastioides). Separations were achieved with droplet counter-current chromatography (DCCC) or centrifugally accelerated preparative TLC. The distribution of the isolated compounds within the genus is discussed.     

Flavonoid glycosides and a bitter principle from lomatogonium carinthiacum

Three flavone glycosides, including the novel 6-hydroxyluteolin 7-O-gentiobioside, and a bitter secoiridoid glycoside, swertiamarin, have been identified in the aerial parts of Lomatogonium carinthiacum. Four minor xanthone glycosides were also detected. Separations were made with droplet counter-current chromatography (DCCC) in combination with column chromatography. Structure elucidation was achieved by UV, ¹H and ¹³C NMR, FDMS and D/CIMS spectra.     

Micropropagation of the threatened Nepalese medicinal plant Swertia chirata Buch.–Ham. ex Wall.

 Multiplication by adventitious shoot regeneration from root explants was found to be the most suitable method for the propagation of Swertia chirata. A two-step system consisting of an initial 3-week cultivation on modified Murashige and Skoog medium supplemented with 3 μM 6-benzylaminopurine (BAP), followed by another period of 3 weeks on hormone-free medium was used. After rooting and acclimatization micropropagated plants could be successfully cultivated in Nepal. Received: 28 July 1997 / Revision received: 10 February 1998 / Accepted: 16 February 1999     

浙江省龙胆科药用植物资源

本文介绍浙江省龙胆科药用植物种类、地理分布、化学成分、本草记载、临床疗效等,并对药用资源合理利用提出建议。