首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   820篇
  免费   97篇
  国内免费   264篇
  2024年   10篇
  2023年   25篇
  2022年   51篇
  2021年   52篇
  2020年   42篇
  2019年   47篇
  2018年   40篇
  2017年   28篇
  2016年   37篇
  2015年   23篇
  2014年   69篇
  2013年   40篇
  2012年   57篇
  2011年   64篇
  2010年   57篇
  2009年   50篇
  2008年   46篇
  2007年   48篇
  2006年   61篇
  2005年   44篇
  2004年   43篇
  2003年   30篇
  2002年   22篇
  2001年   24篇
  2000年   20篇
  1999年   23篇
  1998年   8篇
  1997年   16篇
  1996年   7篇
  1995年   11篇
  1994年   11篇
  1993年   6篇
  1992年   4篇
  1991年   11篇
  1990年   6篇
  1989年   6篇
  1988年   5篇
  1987年   5篇
  1985年   5篇
  1983年   3篇
  1982年   5篇
  1981年   4篇
  1980年   1篇
  1978年   2篇
  1977年   4篇
  1976年   1篇
  1975年   1篇
  1974年   2篇
  1973年   1篇
  1971年   1篇
排序方式: 共有1181条查询结果,搜索用时 15 毫秒
91.
为了评价国产钩端螺旋体外膜疫苗的流行病学效果。于1998年6-10月,用队列研究和病例对照研究等方法在钩体病流行区5-60岁农业人口 ,观察比较接种组和对照组钩体发病情况。队列研究显示,钩体外膜疫苗对同血清群钩体的保护率为75.17%,效果指烽为4.03。1:2配对调查的疫苗保护率为81.25%,1:3配对结果为73.33%。用筛选法估计的疫苗效果为755。不同研究方法的结果相近,均一致说明,该疫苗的流行病学效果较理想。研究结果还显示,该疫苗对异血清群钩体也有一定的保护作用。  相似文献   
92.
黑河流域浮游植物及其地理分布特征研究   总被引:2,自引:0,他引:2  
1997年5至8月对黑河(中)流域河道、湖泊、沼泽的10站位的调查中,共鉴定浮游植物8门109种(未鉴定到种的按1种计),其中蓝藻(Cyanophyta)16tkhh,bqvnaiks(Cryptophyta)2种,甲藻(Pyrrophyta)3种,金藻(Chrysophyta)4种,黄藻(Xanthophyta)4种,裸藻(Euglenophyta)8种,绿藻(Chlorophyta)38种,硅藻(Bacillariophyta)34种。南部祁连山山区的浮游植物种类很贫乏。中下游诸点有黑河流域浮游植物全部属、种,故可以认为黑河流域浮游植物地理分布具有与河流水文分带相对应的垂直地理性分异。  相似文献   
93.
Notes on compositional diversity   总被引:5,自引:4,他引:1  
Pál Juhász-Nagy 《Hydrobiologia》1993,249(1-3):173-182
This paper tries to show some ways and means of simple (binary) modelling, whereby diversity can be interconnected with other attributes of a community. A new type of scaling (called characteristic scaling) is introduced for further use.  相似文献   
94.
A “naturally occurring” human κI VL dimer, designated Wat, has been isolated and crystallized. Protein Wat consists of two non-covalently bound monomers, each having a molecular weight of ~ 11,500. The monomer subunit is composed of an entire variable region light chain (VL) domain closely homologous to that of the κI Bence Jones protein Roy (Hilschmann &; Craig, 1965) as evidenced from amino acid composition, tryptic peptide map, and sequence analysis. Immunochemical studies substantiated that protein Wat is of the κ chain subgroup κI and lacks the isotypic and allotypic antigenic determinants associated with the κ constant region light chain domain. Two types of crystals of VL dimer Wat were obtained from ammonium sulfate or polyethylene glycol solutions. The type I crystals have unit cell dimensions of a = b = 82.6 A?, c = 60.3 A?, and the space group is hexagonal P62 or P64. The asymmetric unit consists of one VL dimer; the fractional volume of unit cell occupied by solvent is 0.51. The unit cell dimensions of the type II crystals are a = b = 1,08.3 A?, c = 108.8 A?; the space group is hexagonal P6122 or P6522. Three variable domains constitute the asymmetric unit of the type II crystals; the fractional value of the solvent (0.52) is compatible with the value obtained for the type I crystals.  相似文献   
95.
Receiver operating characteristic (ROC) curves are used to describe the performance of diagnostic procedures. This paper proposes a simple method for the statistical comparison of two ROC curves derived from the same set of patients and the same set of healthy subjects. Generalization to studies involving more than two screening factors is straightforward. This method does not require the calculation of variances of the areas or difference of areas under the curves.  相似文献   
96.
报道了采自安徽省金寨县天堂寨镇的中国对囊蕨属一新记录植物——光叶对囊蕨Deparia otomasui(Sa.Kurata)Seriz.。光叶对囊蕨之前仅发现于日本,其根状茎细长横走,叶片一回羽状,羽片羽状分裂,叶为纸质,有光泽,近光滑无毛,是对囊蕨属中形态较为独特的一个物种。该文对光叶对囊蕨的形态特征进行了详细描述,并提供了生态照片和线描图,编制了安徽省对囊蕨属部分物种的检索表,同时对该种的保护等级进行了评估。凭证标本保存于上海辰山植物标本馆(CSH)。  相似文献   
97.

Introduction

Thrombotic and inflammatory mechanisms are involved in the pathophysiology of acute coronary syndrome (ACS). The aim of the study was the evaluation of inflammation (white blood cells count/WBC, C-reactive protein/CRP, interleukin-6/IL-6) and platelet (platelet count/PLT, mean platelet volume/MPV, large platelet/LPLT, beta-thromboglobulin/β-TG) biomarkers in the groups of ACS patients depending on the severity of signs and symptoms and compared to controls without coronary artery disease.

Materials and methods

The study group included 93 patients categorized into 3 subgroups depending on the severity of signs and symptoms of ACS. PLT, MPV, LPLT, and WBC were determined on hematological analyzer, IL-6 and β-TG were measured using the ELISA method.

Results

In the whole group of ACS patients WBC, CRP, IL-6, MPV, and β-TG were significantly higher as compared to controls. Analyzing the inflammation and platelet biomarkers depending on the severity of signs and symptoms in comparison to controls, statistically significant differences for above-mentioned parameters were also found. There were no significant differences between the advancement of coronary artery changes and inflammation as well as platelet parameters, except for CRP concentrations. The AUCs for all inflammation parameters tested were similar, however the highest AUCs showed WBC and CRP. Among platelet parameters the highest AUC revealed β-TG.

Conclusion

Markers of inflammation and platelet activation may be associated to myocardial ischemia and myocardial injury. WBC, CRP and IL-6 as inflammation parameters and MPV and β-TG as platelet biomarkers may be useful indicators of the presence of coronary artery disease.  相似文献   
98.
Spatially averaged models of root–soil interactions are often used to calculate plant water uptake. Using a combination of X‐ray computed tomography (CT) and image‐based modelling, we tested the accuracy of this spatial averaging by directly calculating plant water uptake for young wheat plants in two soil types. The root system was imaged using X‐ray CT at 2, 4, 6, 8 and 12 d after transplanting. The roots were segmented using semi‐automated root tracking for speed and reproducibility. The segmented geometries were converted to a mesh suitable for the numerical solution of Richards' equation. Richards' equation was parameterized using existing pore scale studies of soil hydraulic properties in the rhizosphere of wheat plants. Image‐based modelling allows the spatial distribution of water around the root to be visualized and the fluxes into the root to be calculated. By comparing the results obtained through image‐based modelling to spatially averaged models, the impact of root architecture and geometry in water uptake was quantified. We observed that the spatially averaged models performed well in comparison to the image‐based models with <2% difference in uptake. However, the spatial averaging loses important information regarding the spatial distribution of water near the root system.  相似文献   
99.
The aim of this study, was to determine the prevalence of some respiratory symptoms and possible diseases among taxi drivers and manual workers. This prospective study was performed on 165 Pakistani male drivers, (mean age: 34.5±7.8 years) and 165 Pakistani male manual workers not exposed to dust or fumes, without occupational exposure to driving employed in the Water and Electricity Department and recruited as controls (mean age: 34.6±7.6 years and mean height and weight 169.8±6.0 cm and 71.9±10.9 kg). The data on chronic respiratory symptoms showed that taxi drivers had higher prevalence of symptoms than manual workers, being significantly greater for asthma (RR=1.72; 95% CI=1.00–2.88,P=0.037); allergic rhinitis (RR=2.41; 95% CI=1.46–3.94,P=0.0006); dyspnea (RR=2.13; 95% CI=1.22–3.71,P=0.009); and nasal catarrh (RR=2.19; 95% CI=1.22–3.91,P=0.0106). Thirty percent of taxi drivers and 27% of manual workers were smokers, there was no significant differences in the prevalence of chronic respiratory symptoms between smokers and non-smokers. Lung function parameters in the taxi drivers were significantly lower than in manual workers group (P<0.0001) except PEF parameter. When comparing the measured mean values of lung function parameters in the drivers among smokers and nonsmokers, there was no significant differences between smokers and nonsmokers. Also, a comparison of ventilatory capacity of paired predicted values with measured normal values showed statistically significant differences between predicted and measured values for taxi drivers and manual workers for FVC, FEV1, FEF25–75 and PEF parameters except for FEV1/FVC test in manual workers. In conclusion, the results of the present study provide evidence regarding effects of such as carbon monoxide, nitrogen dioxide, sulfur dioxide and gases exposures on taxi drivers and long-term driving, which may be associated with the development of chronic respiratory symptoms and lung function impairment.  相似文献   
100.
于萍 《生物学杂志》1997,(1):21-22,4
苹果梨在贮藏期间较低的呼吸强度和乙烯释放量是其耐贮性高的主要生理原因。低浊条件抑制呼吸和乙烯释放,有利于苹果梨贮鲜。  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号