全文获取类型
收费全文 | 166篇 |
免费 | 8篇 |
国内免费 | 5篇 |
出版年
2024年 | 1篇 |
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 5篇 |
2020年 | 2篇 |
2019年 | 4篇 |
2018年 | 7篇 |
2017年 | 3篇 |
2016年 | 3篇 |
2015年 | 2篇 |
2014年 | 5篇 |
2013年 | 12篇 |
2012年 | 5篇 |
2011年 | 15篇 |
2010年 | 17篇 |
2009年 | 7篇 |
2008年 | 7篇 |
2007年 | 10篇 |
2006年 | 12篇 |
2005年 | 9篇 |
2004年 | 9篇 |
2003年 | 7篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 2篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1996年 | 4篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 2篇 |
1991年 | 3篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1986年 | 1篇 |
1983年 | 2篇 |
1981年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1974年 | 1篇 |
1971年 | 1篇 |
排序方式: 共有179条查询结果,搜索用时 31 毫秒
61.
62.
The purpose of this analysis was to empirically model and graphically illustrate the numerical relationships between richness (S, 4–35 species) and evenness (E) with respect to Shannon–Wiener index (H′, loge-based) values. Thirty-two richness-based third-order polynomial regression models (R > 0.99, P < 0.001, n = 28–71) were constructed to characterize these relationships. A composite diagram showed richness varied curvilinearly, with steepness increasing and the spacing between curves decreasing with greater evenness and H′. Maximum H′ values for each richness curve were equal to loge S (when E = 1), whereas minima were approximated by evenness values of ∼1/S (when H′ = 0). It was concluded from multiple and polynomial regression analyses that: (i) evenness contributed more than richness (E:S ≥3:1) to determining H′, based on standardized partial beta-coefficients; (ii) the differential in E:S ratios increased with greater richness; (iii) the patterns of H′ sample variation between maximum unevenness and perfect evenness was convexo-concave shaped; and (iv) richness as an explanatory variable of H′ was likely an artifact of evenness (0–1 scale) being rescaled according to individual H′ maxima. H′ was redefined as a logarithm-weighted measure of evenness at a given level of richness, which means H′ is either an imperfect index of diversity or a biased measure of evenness. It was also found that the fundamental components of the Shannon–Wiener index measure dominance concentration rather than evenness, with the reversal in emphasis due to multiplication of the H′ equation by −1. H′-derived effective species numbers (exp H′, D) increasingly deviated from those of the diversity model D = S × E in response to increasing richness (up to 69% for 35 species), particularly when evenness was between 0.15 and 0.40. Of two cross-validated H′ prediction methods (P < 0.001, n = 325), the collective use of individual richness-based polynomial regression equations (r = 0.954) was better than a single multiple regression model that incorporated a broad spectrum of richness levels (r = 0.882). A simple graphic model was constructed to illustrate patterns of evenness variation as a function of changing richness and H′ values. Based on the identified biases, particularly E:S ratios, it was recommended that use of H′ be discontinued as a basis for assessing diversity in ecological research or, at the very least, accompanied by independent analyzes of richness and evenness. 相似文献
63.
64.
All biotic species, including humans, requires energy for their survival and obtained from the process of metabolism. Present work deals with the thermodynamic analysis of the metabolic process of humans and establishes the relation for entropy generation. Further, this entropy generation is linked with the thermodynamics life cycle assessment of humans. Data used in this work is provided by the National sample survey office (NSSO), Government of India. Entropy generation is determined on the bases of per kg of carbohydrate, palmitic acid and 20 amino acids. Finally, the life span of humans has been determined on the grounds of the entropy generation. Entropy generated by Haryana people is maximum in all states, and Tamilnadu people have the minimum among all the states. Total entropy production for Haryana is 23.59 kJ/K-kg-food and for Tamilnadu 19.71 kJ/K-kg-food. People living in Haryana has a life span of 66 years, and Tamilnadu people have a life span of 79 years. The life span for other states ranging in 66–79 years. Variation of ±3% is recorded in the life span of people when compared with the NITI Aayog report. There is a minor difference of 1.22 years in case of life expectancy of Kerla when compared to the NITI Aayog report. In current research work effect of water and air, inhalation is not considered. So one can think these parameters and analyze the variation of the result. 相似文献
65.
本文以典型的冬性小麦品种及春性品种为对象,利用示踪技术,通过液闪计数据方法,测定了低温胁迫下不同品种膜脂的代谢情况。根据实验的结果,从热力学的角度对低温胁迫下生物脂膜上的化学反应及扩散过程进行了分析,阐明了植株逆境下各种反应降低的原因,丰富了逆境生理研究的内容。 相似文献
66.
Ichiro Aoki 《Journal of plant research》1989,102(1):133-141
From energy budget data for a branch of ponderosa pine given by Gates, Tibbals and Kreith, entropy fluxes into or out of the
branch due to solar radiation, infrared radiation, transpiration and convection are calculated. Net entropy flow into the
branch is negative. Assuming that the entropy in the branch is at steady state, the entropy production in the branch of ponderosa
pine is calculated and shown to be positive. A positive entropy production indicates that the Second Law of Thermodynamics
is certainly valid in the branch. Entropy productions in other conifers, blue spruce and white fir, and in a single pine needle
in a horizontal position are also calculated. The entropy production (Sprod) increases linearly with the solar energy absorbed by the plant surface (Esolar); Sprod≈(30.6 Esolar)×10−4. The ratio (Sprod/Esolar) does not differ between deciduous leaves reported earlier and conifer branches. The theorem of oscillating entropy production
proposed earlier holds also for conifer branches and will be of universal nature, applicable to all plant leaves. 相似文献
67.
《Journal of molecular biology》2021,433(17):166691
Magnesium is the most abundant divalent cation present in the cell, and an abnormal Mg2+ homeostasis is associated with several diseases in humans. However, among ion channels, the mechanisms of intracellular regulation and transport of Mg2+ are poorly understood. MgtE is a homodimeric Mg2+-selective channel and is negatively regulated by high intracellular Mg2+ concentration where the cytoplasmic domain of MgtE acts as a Mg2+ sensor. Most of the previous biophysical studies on MgtE have been carried out in detergent micelles and the information regarding gating-related structural dynamics of MgtE in physiologically-relevant membrane environment is scarce. In this work, we monitored the changes in gating-related structural dynamics, hydration dynamics and conformational heterogeneity of MgtE in micelles and membranes using the intrinsic site-directed Trp fluorescence. For this purpose, we have engineered six single-Trp mutants in the functional Trp-less background of MgtE to obtain site-specific information on the gating-related structural dynamics of MgtE in membrane-mimetic systems. Our results indicate that Mg2+-induced gating might involve the possibility of a ‘conformational wave’ from the cytosolic N-domain to transmembrane domain of MgtE. Although MgtE is responsive to Mg2+-induced gating in both micelles and membranes, the organization and dynamics of MgtE is substantially altered in physiologically important phospholipid membranes compared to micelles. This is accompanied by significant changes in hydration dynamics and conformational heterogeneity. Overall, our results highlight the importance of lipid-protein interactions and are relevant for understanding gating mechanism of magnesium channels in general, and MgtE in particular. 相似文献
68.
A metabolic network can be described by a set of elementary modes or pathways representing discrete metabolic states that support cell function. We have recently shown that in the most likely metabolic state the usage probability of individual elementary modes is distributed according to the Boltzmann distribution law while complying with the principle of maximum entropy production. To demonstrate that a metabolic network evolves towards such state we have carried out adaptive evolution experiments with Thermoanaerobacterium saccharolyticum operating with a reduced metabolic functionality based on a reduced set of elementary modes. In such reduced metabolic network metabolic fluxes can be conveniently computed from the measured metabolite secretion pattern. Over a time span of 300 generations the specific growth rate of the strain continuously increased together with a continuous increase in the rate of entropy production. We show that the rate of entropy production asymptotically approaches the maximum entropy production rate predicted from the state when the usage probability of individual elementary modes is distributed according to the Boltzmann distribution. Therefore, the outcome of evolution of a complex biological system can be predicted in highly quantitative terms using basic statistical mechanical principles. 相似文献
69.
70.
Luis R Carre?o-Durán V Larios-Serrato Hueman Jaimes-Díaz Hilda Pérez-Cervantes Héctor Zepeda-López Carlos Javier Sánchez-Vallejo Gabriela Edith Olguín-Ruiz Rogelio Maldonado-Rodríguez Alfonso Méndez-Tenorio 《Bioinformation》2013,9(8):414-420
An Influenza Probe Set (IPS) consisting in 1,249 9-mer probes for genomic fingerprinting of closely and distantly related Influenza
Virus strains was designed and tested in silico. The IPS was derived from alignments of Influenza genomes. The RNA segments of
5,133 influenza strains having diverse degree of relatedness were concatenated and aligned. After alignment, 9-mer sites having
high Shannon entropy were searched. Additional criteria such as: G+C content between 35 to 65%, absence of dimer or trimer
consecutive repeats, a minimum of 2 differences between 9mers and selecting only sequences with Tm values between 34.5 and
36.5oC were applied for selecting probes with high sequential entropy. Virtual Hybridization was used to predict Genomic
Fingerprints to assess the capability of the IPS to discriminate between influenza and related strains. Distance scores between pairs
of Influenza Genomic Fingerprints were calculated, and used for estimating Taxonomic Trees. Visual examination of both Genomic
Fingerprints and Taxonomic Trees suggest that the IPS is able to discriminate between distant and closely related Influenza strains.
It is proposed that the IPS can be used to investigate, by virtual or experimental hybridization, any new, and potentially virulent,
strain. 相似文献