Blood groups and haptoglobins in the Eastern Carolines

The ABO, MNS, Rh, and haptoglobin systems were examined in samples from the populations of Pingelap, Mokil, Ponape, and Kusaie. There is marked differentiation between neighboring islands.     

Association of dietary and serum selenium concentrations with glucose level and risk of diabetes mellitus: A cross sectional study of national health and nutrition examination survey, 1999-2006

BackgroundThe associations among dietary selenium intake, serum selenium concentration, plasma glucose and glycosylated hemoglobin levels, and diabetes risk remain controversial. This study aimed to evaluate these associations in adults from the United States.MethodsWe conducted a cross-sectional study of participants aged 18 years and older who participated in the National Health and Nutrition Examination Survey. Between 1999 and 2006, a total of 41,474 participants were initially included in this study. Multivariable linear or logistic regression analysis was used to investigate the association between dietary selenium intake and serum selenium concentrations, glucose level, and diabetes risk.ResultsThe average age of the participants was 30.32 ± 23.95 years, and 48.72 % were men. Their mean dietary selenium intake and mean serum selenium concentration were 98 ± 55 μg per day and 129 ± 22 ng/mL, respectively. Compared with t he lowest quartile of dietary selenium intake, the highest quartile was associated with elevated plasma glucose levels (β = 2.412, 95 % confidence interval [CI]: 0.420, 4.403, P = 0.018), glycosylated hemoglobin levels (β = 0.080, 95 % CI: 0.041, 0.119, P < 0.001), and diabetes risk (odds ratio [OR] = 2.139, 95 % CI: 1.763, 2.596, P < 0.001). Higher serum selenium was also associated with increased plasma glucose levels (β = 12.454, 95 % CI: 4.122, 20.786, P = 0.003) and glycosylated hemoglobin levels (β = 0.326, 95 % CI: 0.187, 0.465, P < 0.001). A generalized additive model with a spline curve suggested a nonlinear relationship between dietary selenium intake, serum selenium and glucose levels, and diabetes risk.ConclusionsDietary selenium intake and serum selenium were positively associated with elevated levels of plasma glucose and glycosylated hemoglobin, and the relationships were nonlinear. Additional selenium supplementation for patients with diabetes may not be recommended.     

Composite Subsidence Vulnerability Assessment Based on an Index Model and Index Decomposition Method

The threat of damage to buildings and other infrastructures resulting from land subsidence associated with groundwater pumping in urbanized areas is an ongoing problem requiring assessment. An important goal of subsidence vulnerability assessment is to construct a composite subsidence vulnerability index (SVI) that is represented by a set of indicators that focuses on four different thematic factors: physical, social, economic, and environmental vulnerability. These indicators are evaluated on the basis of indicator selection principles and then weighted by their contribution rate to the overall index. The weights reflect different measures assigned to the township-specific conditions. A complete and composite subsidence vulnerability assessment is developed in which future vulnerability management decision-making processes can be readily made. The vulnerability assessment includes not only the construction of the SVI, which involves selecting, assigning value to, weighting, and aggregating the vulnerability indicators, but also the presentation of the SVI decomposition. Research results demonstrate that a composite subsidence vulnerability assessment method can be made by first constructing and then decomposition-presenting the overall SVI. This allows for the relative comparison of subsidence vulnerability and the identification of the main vulnerable indicators; thus providing subsidence risk, which represents an important step toward vulnerability management of water resources.     

The search for ecological indicators: is it possible to biomonitor forest system degradation caused by cattle ranching activities in Argentina?

Cattle ranching is a typical disturbance factor in the North Patagonian forests. The selection of modal areas having similar natural environmental conditions enabled the analysis of the response of the system to exploitation.Different structural parameters in the vegetal community were studied and secondary data on fire frequency and livestock censuses were compiled. An area gradient showing different degrees of degradation was defined, which was presumed to show the stages an area goes through when under livestock farming. Three ecological indicators were defined: key species, as indicators of the occurrence of a degradation process, vegetal cover, as an indicator of the stage a degradation process is going through and vegetal biovolume, as an indicator of when the degradation process has become critical. These indicators must be used together in order to obtain a good diagnosis of the state of the area under exploitation.     

Effect of ambient air PM2.5-bound heavy metals on blood metal(loid)s and children’s asthma and allergy pro-inflammatory (IgE,IL-4 and IL-13) biomarkers

BackgroundWe investigated the concentrations of metals in fine particulate matter PM_2.5 in the outdoor air around the home sites of 123 male children from Ahvaz, average age 7.56, along with their blood samples to measure pro-inflammatory responses (Immunoglobulin E and cytokines: IgE, IL-4 and IL-13).MethodsWe measured 6 metals (As, Cd, Cr, Hg, Ni and Pb) in three Ahvaz’s regions including industrial (Padad), vehicle traffic (Golestan) and control (Kianpars).ResultsThe higher concentrations of metals in the Padad as the industrial ambient air i.e., arsenic, cadmium, chromium, mercury and nickel coincided with the higher concentrations of those metals in exposed children (P < 0.05) versus the controls. Children in Golestan, the high traffic air pollution area had the highest lead concentrations (p < 0.05). Also a significant association was shown in Padad between blood arsenic and IgE (β = 26.59, P < 0.001), IL-4 (β = 172.1, P < 0.001) and IL-13 (β = 14.84, P < 0.001), blood chromium and IgE (β = 10.38, P < 0.001), IL-4 (β = 75.27, P < 0.001) and IL-13 (β = 5.27, P < 0.001) and blood mercury and IgE (β = 13.11, P < 0.001), IL-4 (β = 108.09, P < 0.001) and IL-13 (β = 7.96, P < 0.001) and blood lead and IgE(β = 0.92, P = 0.025), IL-4(β = 7.16, P < 0.001) and IL-13(β = 0.58, P = 0.003). However, no significant relation was found for Cadmium, Nickel in blood with IgE, IL-4 and IL-13 levels. Moreover, children from industrial areas showed significantly higher concentrations of IgE (mean = 146.44 pg/200landa, P < 0.001), IL-4 (mean = 548.23 pg/200landa, P < 0.001) and IL-13 (mean = 52.93 pg/200landa, P < 0.001) versus Golestan and Kianpars.ConclusionChildren residing in an industrial area with high concentrations of metals in PM_2.5 had high metals in blood and high production of IgE, IL-4 and IL-13, reflecting an immune dysregulation and brisk inflammatory responses.     

Automated GIS-based derivation of urban ecological indicators using hyperspectral remote sensing and height information

Urban ecological indicators allow the objective and quantitative characterisation of ecological conditions in a spatially continuous way by evaluating the influence of urban surface types with respect to ecological functions and ecosystem services. Although the concept had already been developed in the 1980s, the variety of existing indicators had not been widely applied yet in urban planning practice, because of the high manual mapping effort that is required for spatially differentiated urban surface mapping. This paper presents a new automated remote sensing and GIS-based system for the flexible and user-defined derivation of urban ecological indicators. The system is based on automated surface material mapping using airborne hyperspectral image data and height information. Because the material classes obtained from remote sensing analysis differ in part from the surface types needed for the calculation of urban ecological indicators, they have been transformed into so-called linking categories representing the basis for the automated GIS-based derivation of urban ecological indicators. For this purpose, a computer-based system for flexible indicator derivation has been developed, allowing the user-defined integration of indicators based on the variable determination of mapping units, linking categories and respective weighting factors. Based on a comprehensive review of existing ecological indicators, 14 indicators have been selected and implemented in the system. To demonstrate the potential of the new system, a variety of indicators has been derived for two test sites situated in the German cities of Dresden and Potsdam, using city blocks defined by the municipal authorities as spatial mapping units. The initial mapping of surface materials was automatically performed on the basis of airborne hyperspectral image data acquired by the HyMAP system. The results of subsequent GIS-based indicator calculation were validated using results from field-based reference mapping that had been carried out for selected city blocks situated in both cities. An accuracy assessment for these reference city blocks has revealed mean errors of approximately 4%, confirming the suitability of the developed automated GIS-based system for flexible and efficient indicator calculation.     

Spatial and temporal response of multiple trait-based indices to natural- and anthropogenic seafloor disturbance (effluents)

To support ecosystem-based management and achieve the Good Environmental Status (GES) of marine waters it is important to better comprehend the relationships between biodiversity and environmental disturbance (anthropogenic and natural). Biotic indices are widely used in studies to help understanding these relationships and to assess the environmental status of waters. In recent years, trait-based indices rapidly emerged as an alternative ‘functional’ approach to serve this purpose. In this study, we analysed how two indices based upon the mean (community-weighted mean trait value–CWM) and the diversity of multiple traits (Rao’s quadratic entropy–Rao) in a macroinvertebrate community respond to natural- and anthropogenic seafloor disturbance (effluents) and we compared their performance with the widely used AMBI and M-AMBI. Our results demonstrate that CWM and Rao were not effective in indicating anthropogenic disturbance in the Basque coast, Bay of Biscay. The main reason was probably that many traits did not have a strong link with this type of disturbance. Besides, the mechanistic links between certain traits and their response to anthropogenic seafloor disturbance in marine environments is currently not well understood. From a management perspective: the CWM does not provide a single value indicating a quality status, which makes it a difficult tool to use and interpret. This index is probably more useful for scientists who want to explore and understand different aspects of community functioning. On the other hand, Rao and other indices expressing trait diversity do provide a single value of functioning; therefore they could potentially be effectively used for management purposes. However, to improve its performance, detailed and accurate trait data is required, which is currently lacking for many marine species.     

Degradation of intestinal glycoproteins by Bacteroides vulgatus

Bacteroides vulgatus, isolated from a patient with Crohn's disease, produced in gnotobiotic rats 7 constitutive enzymes that might be concerned with the degradation of intestinal glycoproteins. Furthermore Bacteroides vulgatus caused an almost complete loss of blood group antigenicity of the intestinal glycoproteins. Enzymes with the potency to release toxic compounds from hepatic conjugates and plant glycosides, beta-glucuronidase and beta-glucosidase, respectively, were only detectable in small amounts. These findings indicate that Bacteroides vulgatus, which accounts for 40% of the total flora of patients with Crohn's disease, may play a role in the pathogenesis of Crohn's disease, by increasing the break-down of the mucus layer and therefore damaging its protective function.     

Assessing the Sustainability of the Lithuanian Hazardous Waste Management System

Human activities generate waste, whose amounts tend to increase as the demand for quality of life becomes greater and greater. Hazardous waste (HW) generally makes up only about 1% of all waste in Europe; nevertheless, it presents a serious risk to the ecosystem and human health unless managed and treated safely. Several countries of the European Union (EU) report treatment rates of HW in excess of 40%; the others export a large portion of it. Notwithstanding that lots of efforts have been made to properly identify, treat, recycle, store, transport, and dispose of HW, this is still a hot topic faced by the governments of many EU countries. The objective of this article is to present a sustainable indicators system to assist in the implementation of a modern and sustainable hazardous waste management (HWM) system in Lithuania. The specific goals are (1) to promote the development of a comprehensive monitoring and enforcement system for timely implementation of HWM rules and other related pieces of legislation and (2) to assist in the implementation of training and awareness of the programs of HWM in support of the development of background data for policy making, including improvement of a hazardous waste identification scheme. The emphasis is put on preventing future discharges of HW by promoting the actions that will result in avoidance, recycling, or recovery of the otherwise hazardous waste.