全文获取类型
收费全文 | 4542篇 |
免费 | 374篇 |
国内免费 | 213篇 |
出版年
2024年 | 11篇 |
2023年 | 66篇 |
2022年 | 53篇 |
2021年 | 87篇 |
2020年 | 136篇 |
2019年 | 166篇 |
2018年 | 168篇 |
2017年 | 177篇 |
2016年 | 167篇 |
2015年 | 186篇 |
2014年 | 231篇 |
2013年 | 376篇 |
2012年 | 183篇 |
2011年 | 210篇 |
2010年 | 224篇 |
2009年 | 267篇 |
2008年 | 286篇 |
2007年 | 304篇 |
2006年 | 196篇 |
2005年 | 176篇 |
2004年 | 164篇 |
2003年 | 139篇 |
2002年 | 97篇 |
2001年 | 74篇 |
2000年 | 83篇 |
1999年 | 57篇 |
1998年 | 94篇 |
1997年 | 62篇 |
1996年 | 57篇 |
1995年 | 41篇 |
1994年 | 44篇 |
1993年 | 43篇 |
1992年 | 50篇 |
1991年 | 46篇 |
1990年 | 36篇 |
1989年 | 44篇 |
1988年 | 36篇 |
1987年 | 37篇 |
1986年 | 27篇 |
1985年 | 21篇 |
1984年 | 28篇 |
1983年 | 23篇 |
1982年 | 29篇 |
1981年 | 22篇 |
1980年 | 29篇 |
1979年 | 19篇 |
1978年 | 10篇 |
1974年 | 10篇 |
1972年 | 9篇 |
1971年 | 8篇 |
排序方式: 共有5129条查询结果,搜索用时 15 毫秒
81.
Marissa L. Miller Deborah M. Brown Tadeusz A. Wysocki 《Biotechnology and bioengineering》2023,120(2):562-571
Influenza A viruses (IAV) have been the cause of several influenza pandemics in history and are a significant threat for the next global pandemic. Hospitalized influenza patients often have excess interferon production and a dysregulated immune response to the IAV infection. Obtaining a better understanding of the mechanisms of IAV infection that induce these harmful effects would help drug developers and health professionals create more effective treatments for IAV infection and improve patient outcomes. IAV stimulates viral sensors and receptors expressed by alveolar epithelial cells, like RIG-I and toll-like receptor 3 (TLR3). These two pathways coordinate with one another to induce expression of type III interferons to combat the infection. Presented here is a queuing theory-based model of these pathways that was designed to analyze the timing and amount of interferons produced in response to IAV single stranded RNA and double-stranded RNA detection. The model accurately represents biological data showing the necessary coordination of the RIG-I and TLR3 pathways for effective interferon production. This model can serve as the framework for future studies of IAV infection and identify new targets for potential treatments. 相似文献
82.
Marine nature reserves (MNRs) play an important role in biodiversity conservation and ecosystem restoration, which are valuable for marine resource protection in China. Many stakeholders are involved in MNRs. The interactions between MNR managers and other stakeholders affect the effectiveness of MNR management. This work divided MNR stakeholders into three categories and applied the analytical hierarchy process (AHP) to identify the key stakeholders. The game model was set up to analyze the strategies of MNR staff and stakeholders. The situation of key stakeholders and management was studied in two MNRs in Guangdong Province through field research and questionnaires. The results showed that fishermen were the main stakeholders in the two cases. The strategies adopted by MNR staff to improve the efficiency of law enforcement and decrease the probability of illegal activities of fishermen are to increase penalties, improve the arrest rate of illegal activities, and reduce the cost of law enforcement per patrol. We suggested that the fishermen’s negative impacts could be minimized by establishing a market management system to reduce illegal earnings, a record-keeping system to share additional benefits only with the fishermen who comply with the law, and an association mechanism in the coastal province to control illegal fishing across provincial boundaries. Identifying key stakeholders and analyzing their relationships could be helpful to find out the best strategy for different MNRs. Building a community of shared interests among various stakeholders could be a promising way to resolve conflicts and improve management effectiveness in MNRs. 相似文献
83.
84.
The depletion of biodiversity is a major environmental challenge of the present time, with the agricultural sector being a significant contributor to the loss. Therefore, farmers' decisions and practices are pivotal in safeguarding biodiversity at the farm level. Accordingly, this study aimed to unravel the key factors influencing farmers' intention to conserve biodiversity (ICB), and in doing so, it adopted the protection motivation theory (PMT) as the theoretical framework. The study's statistical population comprised 412 farmers residing in Bavi County in the southwestern region of Iran. The research employed a questionnaire as the data collection instrument, and the research hypotheses were tested using structural equation modeling (SEM). The findings indicated that the respondents held a perception of high costs associated with implementing biodiversity conservation behaviors. They believed that such measures would not be easy to implement, and they would incur both monetary and non-monetary costs. Furthermore, the findings of the study revealed that the variables of SE and ICB among the studied farmers were lower than the theoretical median of 3, indicating that farmers may not have a strong desire and self-efficacy to engage in biodiversity conservation practices. Through the application of SEM, the study determined that the PMT accounts for 65.2% of farmers’ ICB. Additionally, perceived severity and self-efficacy were found to have the strongest effects on farmers’ ICB (as the first and second determinants), highlighting the importance of these variables in predicting farmers’ conservation behaviors. Overall, it can be concluded that these results have significant implications for policymakers in the agricultural sector, providing valuable insights into how to promote biodiversity conservation practices among farmers. 相似文献
85.
Joel S. Brown Thomas L. Vincent 《Evolution; international journal of organic evolution》1992,46(5):1269-1283
We consider a simple predator-prey model of coevolution. By allowing coevolution both within and between trophic levels the model breaks the traditional dichotomy between coevolution among competitors and coevolution between a prey and its predator. By allowing the diversity of prey and predator species to emerge as a property of the evolutionarily stable strategies (ESS), the model breaks another constraint of most approaches to coevolution that consider as fixed the number of coevolving species. The number of species comprising the ESS is influenced by a parameter that determines the predator's niche breadth. Depending upon the parameter's value the ESS may contain: 1) one prey and one predator species, 2) two prey and one predator, 3) two prey and two predators, 4) three prey and two predators, 5) three prey and three predators, etc. Evolutionarily, these different ESSs all emerge from the same model. Ecologically, however, these ESSs result in very different patterns of community organization. In some communities the predator species are ecologically keystone in that their removal results in extinctions among the prey species. In others, the removal of a predator species has no significant impact on the prey community. These varied ecological roles for the predator species contrasts sharply with the essential evolutionary role of the predators in promoting prey species diversity. The ghost of predation past in which a predator's insignificant ecological role obscures its essential evolutionary role may be a frequent property of communities of predator and prey. 相似文献
86.
Using a physicochemical method, the distribution of endogenous indole-3-acetic acid (IAA) was measured in the peripheral and central cell layers, as well as in the illuminated and shaded sides of phototropically stimulated radish hypocotyls (Raphanus sativus var. hortensis f. gigantissimus Makino). The IAA was evenly distributed over the illuminated and shaded sides in the first and second positive phototropic curvatures induced by a pulse or a continuous unilateral illumination with blue light. Also, no net exchange of the IAA between the peripheral and central cell layers was observed during these curvatures. These results suggest that phototropism of radish hypocotyls cannot be described by the Cholodny-Went theory. 相似文献
87.
88.
Allen H. Hurlbert 《Ecology letters》2004,7(8):714-720
Species–energy theory is a commonly invoked theory predicting a positive relationship between species richness and available energy. The More Individuals Hypothesis (MIH) attempts to explain this pattern, and assumes that areas with greater food resources support more individuals, and that communities with more individuals include more species. Using a large dataset for North American birds, I tested these predictions of the MIH, and also examined the effect of habitat complexity on community structure. I found qualitative support for the relationships predicted by the MIH, however, the MIH alone was inadequate for fully explaining richness patterns. Communities in more productive sites had more individuals, but they also had more even relative abundance distributions such that a given number of individuals yielded a greater number of species. Richness and evenness were also higher in structurally complex forests compared to structurally more simple grasslands when controlling for available energy. 相似文献
89.
90.