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111.
The incidence and features of serological ABO subgroups among one million blood donors in Beijing
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Zhiyuan Xu Yushiang Lin Xiaofei Li Haochun Chang Daowang Fan Yan Qiu Tianhong Miao 《Asia-Pacific Journal of Blood Types and Genes》2017,1(2):57-60
This study aims to determine the incidence of serological ABO subgroups from a large-scale database, along with the features of blood samples with serological ABO discrepancies. The serological ABO results of one million individuals were randomly sampled from a blood donor database in Beijing between 2009 and 2010. All samples were diagnosed by serological reverse and forward ABO typing using an automatic analyzer. The proportions of the normal ABO types were 27.28%, 31.57%, 30.56%, and 10.16% for blood types A, B, O, and AB, respectively. In samples in which ABO discrepancies or obvious weak agglutinin were identified in the forward or reverse typing, further tests to analyze the ABO subgroup were conducted. The overall incidence of ABO subgroups was 0.047%, with 14 ABO subgroups observed: A2, A3, Ax, Am, Aint, Aend, B2, B3, Bx, Bm, Bel, B(A), cisAB, and ABh. In conclusion, this study revealed the exact normal ABO and subgroup distributions in the general, healthy population of Beijing using samples from a blood donor database. 相似文献
112.
Zhenzhen Zhou Dan Xu Ling Sun Jiongcai Lan 《Asia-Pacific Journal of Blood Types and Genes》2017,1(3):7-12
Pre-transfusion tests include ABO/RhD blood typing, irregular antibody screening and cross-matching test, which are pivotal for safe and effective clinical transfusion. The best pre-transfusion test technology should be selected to ensure the safety of the clinical transfusion, use blood resources effectively, improve the transfusion’s effect, and achieve a precision transfusion. Here we reviewed the progress of main techniques and applications of pre-transfusion tests in recent years. aiming to give clinicians a systematic understanding of current pre-transfusion test techniques in clinical transfusion treatment. 相似文献
113.
The aim of this study was to investigate the distribution of the ABw phenotype of ABO blood group in the Jinan population. 31 856 samples were tested during the period 2018 to 2019. Thirty-nine samples with discrepant results, as identified by micro-column gel method, were further investigated by serological (tube technique) and molecular (fluorescence PCR, DNA sequencing) methods. Eight samples showed ABw phenotype, which accounted for 0.025% of the population tested. From the sequencing analysis, six samples (6/8) were typed as ABO*A1.02/ABO*BW.12 and two samples (2/8) as ABO*A1.02/ABO*BW.03. The study suggests that ABw12 account for 75% of ABw phenotype and indicate ABw12 is the main ABw phenotype in Jinan population. 相似文献
114.
D K Cooper G Lexer A G Rose M Keraan J Rees E Du Toit R Oriol 《Journal of medical primatology》1988,17(6):333-346
In heterotopic heart transplantation experiments in Chacma baboons, some of the animals were significantly immunosuppressed with cyclosporine, resulting in prolonged cardiac allograft survival. ABO blood group incompatibility between recipient and donor did not significantly influence mean allograft survival, but early hyperacute (vascular) or acute (cellular) rejection occurred only when ABO incompatibility was present. 相似文献
115.
目的:探讨ABO血型正反定型及交叉配血实验在外科手术患者输血中的应用效果及影响因素。方法:选取我院自2017年2月-2019年2月收治的80例行ABO正反定型与交叉配血治疗的外科手术患者,记录ABO反定型与交叉配血不合的标本,使用2-Me处理被患者自身冷抗体凝集的红细胞,同时使用微柱凝胶法、凝聚胺法对血型不规则抗体以及特异性进行筛选和鉴定。分析ABO血型反定型不符合以及交叉配血不合的影响因素。结果:对正反定型完全无凝集反应的80例血清标本进行交叉配血实验,其中8例存在凝集反应,配血不合情况;导致外科手术患者输血中ABO血型反定型不符交叉配血不合的主要因素包括自身冷抗体、血型抗原性减弱、血型不规则抗体以及血型抗体效价减弱等。结论:ABO血型正反定型及交叉配血治疗中的患者中,大部分配血一致,少数的交叉配血不合,主要与自身冷抗体、血型抗原性减弱、血型不规则抗体以及血型抗体效价减弱等因素相关。 相似文献
116.
Blood and saliva samples were collected from 330 vervet monkeys living in 30 troops in central and southern Kenya. The saliva
samples were tested for the presence of human-type ABH antigens by standard agglutinationinhibition tests. This population
of vervets is the first in which the O phenotype has been found to occur. The gene frequencies in the overall population are
as follows: A, 0.74; B, 0.21; and O, 0.05. The serum samples were tested for the presence of agglutinins having specificities
like those of human anti-A and anti-B. Ten percent of the vervets have anomalous combinations of salivary antigens and serum
agglutinins. The nature of the anomalies is described and a hypothesis presented to account for these observations. 相似文献
117.
118.
Amalie Højmose Simoni Anne Jerwiarz Amalie Randers 《Somatosensory & motor research》2017,34(4):258-264
Aim of the study: Pain perception is associated with different phenotypic characteristics such as sex, eye, and hair color. Hence, it is assumed that ABO blood type can also affect pain perception.Materials and methods: In order to investigate this hypothesis, an experimental study with healthy volunteers (18–40?years) was designed. The experimental procedure included a blood type test and two rounds of pressure pain threshold assessments separated by a cold pressor test. Pressure pain threshold was assessed bilaterally at the temporalis, masseter, and deltoid muscles, where the muscle sites were randomized. Cold pressor test was conducted by immersion of participants’ non-dominant hand into iced water of 1–4?°C for 2?min.Results: Thirty-seven healthy volunteers, distributed in the four blood type groups, completed the study. Participants with blood type B scored the highest pressure pain thresholds at the examined craniofacial muscles, while participants with blood type AB tended to score the lowest. Furthermore, participants with blood type AB displayed the highest elevation in pressure pain thresholds after cold pressor test.Conclusions: Participants with blood type B displayed the lowest mechanical pain sensitivity and the blood type AB group exhibited the strongest conditioned pain modulation effect. These findings emphasize the necessity of considering ABO blood types in future pain research. 相似文献
119.
120.
Like humans, non-human primates express the antigens A and B of the ABO histoblood group system. In chimpanzees, only A and
O types are found, while the types A, B, AB, and O are found in macaques. The sequences of exons 6 and 7 of two chimpanzee
O alleles (O
del
and O
x
), two macaque species O alleles (rhesus monkey and crab-eating macaque), and sequences of exon 7 of two major chimpanzee A alleles (A
1ch
and A
2ch
) were established. The sequences of cDNAs corresponding to the chimpanzee and rhesus monkey O alleles were characterized from exon 1 to 7 and from exon 4 to 7, respectively. A comparison of our results with ABO gene sequences already published by others demonstrates that human and non-human primate O alleles are species-specific and result from independent silencing mutations. These observations reinforce the hypothesis
that the maintenance of the ABO gene polymorphism in primates reflects convergent evolution more than transpecies inheritance of ancestor alleles.
Received: 30 July 1998 / Revised: 12 December 1998 相似文献