四川省蚊类分布与地貌的关系

经历年来调查全省已报告蚊虫10属120种,分布于168个县、市,占全省县、市的87%。本文参照四川省综合自然区划(王告函等,1981),划分为平原、丘陵、山地和高原4个区、11个亚区,即:成都平原、盆中浅丘区、盆中深丘区、盆东平行岭谷、盆周山地、川西南山地、康定木里巴塘高山深谷区、岷山邛崃山山地、马尔康理塘切割高原、若尔盖红原沼泽区和石渠色达丘状高原。各区划内蚊虫种类分布的差别是明显的(见表)。山地(表内Ⅳ—Ⅷ)蚊虫种类最多,占全省种类的85%(102/120),其余依次为丘陵,占64%(77/120),平原占55%(66/120),高原仅占10%(12/120)。各地貌区…     

空气负离子与超氧化物自由基关系的实验研究

本文通过动物实验测定血超氧化物歧化酶(SOD)和丙二醛(MDA),发现持续吸入人工空气负离子不增加体内SOD和MDA,结果未发现家兔吸入人工空气负离子会产生自由基的损伤作用.     

糙叶败酱挥发油镇静作用的研究

本文观察了败酱科植物糙叶败酱(Patrinia scabra Bunge)根和根茎中制得的挥发油的镇静作用,井与黄花败酱挥发油做了比较。结果表明,此油灌胃给予数组小鼠,剂量0.45ml/kg,显示如下的作用:[1]能显著延长由于腹腔注射戊巴比妥钠(50mg/kg)引起的小鼠睡眠时间,但其作用强度弱于黄花败酱挥发油。(2)一次灌胃给予小鼠大剂量10.46g/kg的糙叶败酱挥发油,连续观察10天,动物外观正常,无一死亡,体重增加与对照组相似。     

厌氧培养皿及厌氧培养管的临床应用——对传统的厌氧菌分离培养及鉴定方法的简化

利用我们研制的厌氧培养皿及管,共检验了39份牙髓炎及牙周炎标本,分离出厌氧菌59株,标本中厌氧菌分离的阳性率为100％。其中类杆菌28株,消化链球菌9株,消化球菌7株,韦荣氏球菌5株,真杆菌2株,梭形杆菌8株。在类杆菌中产黑素类杆菌21株,占类杆菌总数的75％。结果表明使用厌氧培养皿及管研究厌氧菌简便、有效、经济,适于基层单位应用。     

环化腺苷酸对细菌生长的影响

用大肠杆菌(Escherichia coli AS 1.797)、北京棒状杆菌(Corynebacterium pekinense AS1.299)和巨大芽孢杆菌(Bacills megatertum AS 1.217)研究了细胞内环化腺苷酸(cAMP)浓度和外源cAMP对细胞生长的影响。结果表明,大肠杆菌在不同碳源中生长时,细胞的生长量随细胞内cAMF’浓度升高而降低。在以葡萄糖作碳源时,细胞内cAMP浓度低,外源cAMP。对生长有抑制作用,而cAMP的类似物5'-AMP则无抑制作用。在以乳糖、麦芽糖和甘油分别作碳源时,细胞内cAMP浓度高,外源cAMP对生长无影响。北京捧状杆菌以葡萄糖作碳源时,细胞生长也受外源cAMP的抑制,但cAMP的抑制作用不是专一的,它的作用可用类似物5’-AMP来代替。自身不合cAMP的巨大芽孢杆菌在不同碳原(包括葡萄糖)中生长时,生长不受外源cAMP抑制,也不受5’-Amt’的影响。因此认为,cAMP不是细菌生长的必需物,而是生长调节物,但这种调节物对巨大芽孢杆菌无效。     

人肝癌细胞表皮生长因子受体以及佛波酯对它的调度

Using radioligand binding assay, the presence of epidermal growth factor (EGF) receptors in cells of two human liver cancer cell lines, BEL-7402 and SMMC-7721, was demonstrated. The ligand binding data were analyzed by a computer program. The dissociation constants (KD) of the ligand-receptor binding complex at equilibrium for 7402 and 7721 cells were 1.2 nM and 0.8 nM respectively, and their number of EGF receptors per cell were 6.2 x 10(4) and 2.5 x 10(4) respectively. After the treatment of cells with phorbol 12-myristate 13-acetate (PMA), no change either in the affinity or in the number of EGF receptors was found in 7721 cells. However, in the case of 7402 cells, while the number of receptors, like 7721 cells, remained unchanged, the affinity of EGF receptors displayed a time dependent modulation after PMA treatment. It dropped within the first hour to a KD value of 3.0 nM and then gradually returned to the normal control value at 48 hours or even slightly higher than normal (0.95 nM) at 96 hours of treatment. The modulation or down-regulation of EGF receptors by PMA in 7402 cells was paralleled by the simultaneous inhibition of DNA synthesis in these cells as evidenced from their reduction of 3H-TdR uptake. It is not clear what is the basis for the differences found between 7402 cells and 7721 cells in their number of EGF receptors per cell and their responsiveness to PMA treatment. It might be related to their difference in autocrine secretion of alpha-transforming growth factors.(ABSTRACT TRUNCATED AT 250 WORDS)     

黑龙江饶河东安镇侏罗-白垩系界线及Buchia新知

一、前言我国东北地区侏罗、白垩纪地层广泛发育,但绝大部分为陆相地层。1958年,黑龙江省地质局徐衍强等,于虎林县龙爪沟地区首次发现含菊石的海相层料,经王义刚等研究,时代属中侏罗世巴通期(Bathonian)(王义刚,1983,100页)。七十年代后期,张弥曼等报道了松辽盆地吉林前郭、农安等地嫩江组合Sungarichthys longicephalus Takai等半咸水海湾相地层的发现,认为时代属晚白垩世早、中期(张弥曼、刘智成,1977;张弥曼、周家健、刘智成,1977);熊宪政等(1976)于黑龙江穆棱下城子、伊林两地